TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation.

Autor: O'Leary EM; Section of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois., Tian Y; Section of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois., Nigdelioglu R; Department of Pathology, Loyola University Medical Center, Maywood, Illinois; and., Witt LJ; Division of Geriatrics and Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, The University of California San Francisco, San Francisco, California., Cetin-Atalay R; Section of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois., Meliton AY; Section of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois., Woods PS; Section of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois., Kimmig LM; Section of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois., Sun KA; Section of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois., Gökalp GA; Section of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois., Mutlu GM; Section of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois., Hamanaka RB; Section of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois.

Publikováno v: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2020 Nov; Vol. 63 (5), pp. 601-612.

Glutamine Metabolism Is Required for Collagen Protein Synthesis in Lung Fibroblasts.

Autor: Hamanaka RB; Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, Illinois; and., O'Leary EM; Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, Illinois; and., Witt LJ; Division of Geriatrics and.; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California-San Francisco, San Francisco, California., Tian Y; Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, Illinois; and., Gökalp GA; Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, Illinois; and., Meliton AY; Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, Illinois; and., Dulin NO; Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, Illinois; and., Mutlu GM; Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, Illinois; and.

Publikováno v: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2019 Nov; Vol. 61 (5), pp. 597-606.