Optical Control of Adenosine A 2A Receptor Using Istradefylline Photosensitivity.

Autor: Dumazer A; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France.; MCS, Laboratory of Medicinal Chemistry and Synthesis, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain., Gómez-Santacana X; MCS, Laboratory of Medicinal Chemistry and Synthesis, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain., Malhaire F; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Jopling C; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Maurel D; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Lebon G; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Llebaria A; MCS, Laboratory of Medicinal Chemistry and Synthesis, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain., Goudet C; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2024 Feb 07; Vol. 15 (3), pp. 645-655. Date of Electronic Publication: 2024 Jan 26.

Control of Theta Oscillatory Activity Underlying Fear Expression by mGlu 5 Receptors.

Autor: Matulewicz P; Institute of Pharmacology, Medical University of Innsbruck, Peter-Mayr-Str. 1, 6020 Innsbruck, Austria.; Department of Animal and Human Physiology, Faculty of Biology, University of Gdansk, Jana Bazynskiego 8, 80-309 Gdansk, Poland., Ramos-Prats A; Institute of Pharmacology, Medical University of Innsbruck, Peter-Mayr-Str. 1, 6020 Innsbruck, Austria., Gómez-Santacana X; Laboratory of Medicinal Chemistry & Synthesis (MCS), Department of Biological Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Jordi Girona 18-26, 08034 Barcelona, Spain., Llebaria A; Laboratory of Medicinal Chemistry & Synthesis (MCS), Department of Biological Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Jordi Girona 18-26, 08034 Barcelona, Spain., Ferraguti F; Institute of Pharmacology, Medical University of Innsbruck, Peter-Mayr-Str. 1, 6020 Innsbruck, Austria.

Publikováno v: Cells [Cells] 2022 Nov 10; Vol. 11 (22). Date of Electronic Publication: 2022 Nov 10.

Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations.

Autor: Nasrallah C; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Cannone G; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK., Briot J; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Rottier K; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Berizzi AE; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Huang CY; Swiss Light Source, Paul Scherrer Institute, 5232 Villigen, Switzerland., Quast RB; CBS, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Hoh F; CBS, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Banères JL; IBMM, Université de Montpellier, CNRS, ENSCM, 34093 Montpellier, France., Malhaire F; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Berto L; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Dumazer A; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Font-Ingles J; MCS, Laboratory of Medicinal Chemistry and Synthesis, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain., Gómez-Santacana X; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France; MCS, Laboratory of Medicinal Chemistry and Synthesis, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain., Catena J; MCS, Laboratory of Medicinal Chemistry and Synthesis, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain; SIMChem, Synthesis of High Added Value Molecules, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain., Kniazeff J; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Goudet C; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Llebaria A; MCS, Laboratory of Medicinal Chemistry and Synthesis, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain., Pin JP; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Vinothkumar KR; National Centre for Biological Sciences TIFR, GKVK Post, Bellary Road, Bangalore 560065, India. Electronic address: vkumar@ncbs.res.in., Lebon G; IGF, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France. Electronic address: guillaume.lebon@igf.cnrs.fr.

Publikováno v: Cell reports [Cell Rep] 2021 Aug 31; Vol. 36 (9), pp. 109648.

Mechanistic Insights into Light-Driven Allosteric Control of GPCR Biological Activity.

Autor: Ricart-Ortega M; MCS, Laboratory of Medicinal Chemistry & Synthesis, Department of Biological Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona 08034, Spain.; IGF, CNRS, INSERM, University of Montpellier, F-34094 Montpellier, France., Berizzi AE; IGF, CNRS, INSERM, University of Montpellier, F-34094 Montpellier, France., Pereira V; IGF, CNRS, INSERM, University of Montpellier, F-34094 Montpellier, France., Malhaire F; IGF, CNRS, INSERM, University of Montpellier, F-34094 Montpellier, France., Catena J; MCS, Laboratory of Medicinal Chemistry & Synthesis, Department of Biological Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona 08034, Spain., Font J; IGF, CNRS, INSERM, University of Montpellier, F-34094 Montpellier, France., Gómez-Santacana X; IGF, CNRS, INSERM, University of Montpellier, F-34094 Montpellier, France., Muñoz L; MCS, Laboratory of Medicinal Chemistry & Synthesis, Department of Biological Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona 08034, Spain.; SIMchem, Service of Synthesis of High Added Value Molecules, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona 08034, Spain., Zussy C; IGF, CNRS, INSERM, University of Montpellier, F-34094 Montpellier, France., Serra C; MCS, Laboratory of Medicinal Chemistry & Synthesis, Department of Biological Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona 08034, Spain.; SIMchem, Service of Synthesis of High Added Value Molecules, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona 08034, Spain., Rovira X; MCS, Laboratory of Medicinal Chemistry & Synthesis, Department of Biological Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona 08034, Spain., Goudet C; IGF, CNRS, INSERM, University of Montpellier, F-34094 Montpellier, France., Llebaria A; MCS, Laboratory of Medicinal Chemistry & Synthesis, Department of Biological Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona 08034, Spain.; SIMchem, Service of Synthesis of High Added Value Molecules, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona 08034, Spain.

Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2020 Aug 18; Vol. 3 (5), pp. 883-895. Date of Electronic Publication: 2020 Aug 18 (Print Publication: 2020).

Reversible silencing of endogenous receptors in intact brain tissue using 2-photon pharmacology.

Autor: Pittolo S; Institute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology, 08028 Barcelona, Spain., Lee H; Institute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology, 08028 Barcelona, Spain., Lladó A; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology, 08028 Barcelona, Spain., Tosi S; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology, 08028 Barcelona, Spain., Bosch M; Institute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology, 08028 Barcelona, Spain., Bardia L; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology, 08028 Barcelona, Spain., Gómez-Santacana X; Institute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology, 08028 Barcelona, Spain.; Institute of Advanced Chemistry of Catalonia, Consejo Superior de Investigaciones Científicas (IQAC-CSIC), 08034 Barcelona, Spain., Llebaria A; Institute of Advanced Chemistry of Catalonia, Consejo Superior de Investigaciones Científicas (IQAC-CSIC), 08034 Barcelona, Spain., Soriano E; Department of Cell Biology, Physiology, and Immunology, University of Barcelona (UB), 08028 Barcelona, Spain.; Catalan Institution for Research and Advanced Studies (ICREA), 08010 Barcelona, Spain.; Network Center of Biomedical Research in Neurodegenerative Diseases (CIBERNED), 28031 Madrid, Spain., Colombelli J; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology, 08028 Barcelona, Spain., Poskanzer KE; Department of Biochemistry & Biophysics, University of California, San Francisco (UCSF), CA 94158.; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, CA 94158., Perea G; Cajal Institute, Consejo Superior de Investigaciones Científicas (IC-CSIC), 28002 Madrid, Spain., Gorostiza P; Institute for Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology, 08028 Barcelona, Spain; pau@icrea.cat.; Catalan Institution for Research and Advanced Studies (ICREA), 08010 Barcelona, Spain.; Network Center of Biomedical Research in Bioengineering, Biomaterials, and Nanomedicine (CIBER-BBN), 50015 Zaragoza, Spain.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Jul 02; Vol. 116 (27), pp. 13680-13689. Date of Electronic Publication: 2019 Jun 13.