Synergistic activation of AMPK prevents from polyglutamine-induced toxicity in Caenorhabditis elegans

Autor: Gómez-Escribano, AP, Bono-Yagüe, J, García-Gimeno, MA, Sequedo, MD, Hervás, D, Fornés-Ferrer, V, Torres-Sánchez, SC, Millán, JM, Sanz, P, Vázquez-Manrique, RP ^*

Publikováno v: In Pharmacological Research November 2020 161

Spectroscopic, Electrochemical, and Biological Assays of Copper-Binding Molecules for Screening of Different Drugs and Plant Extracts against Neurodegenerative Disorders

Autor: Brinvillier D, Barrast M, Couderc-Murillo P, Bono-Yagüe J, Rousteau A, Gómez Escribano AP, Palmeira-Mello MV, Doménech-Carbó A, Passe-Coutrin N, Sylvestre M, Vázquez-Manrique RP, Cebrián-Torrejón G

Publikováno v: Acs Omega
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Universitat Rovira i virgili (URV)

Neurodegenerative disorders, caused by prone-to-aggregation proteins, such as Alzheimer disease or Huntington disease, share other traits such as disrupted homeostasis of essential metal ions, like copper. In this context, in an attempt to identify C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::5b3848a614b442e4d90b5be687402cd9
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4037

Reactive Species in Huntington Disease: Are They Really the Radicals You Want to Catch?

Autor: Bono-Yagüe J, Gómez-Escribano AP, Millán JM, Vázquez-Manrique RP

Publikováno v: Antioxidants (Basel, Switzerland)
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Huntington disease (HD) is a neurodegenerative condition and one of the so-called rare or minority diseases, due to its low prevalence (affecting 1-10 of every 100,000 people in western countries). The causative gene,HTT, encodes huntingtin, a protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::d13c29b19829bec19666a54873b899ed
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=12692

Characterization of RAN Translation and Antisense Transcription in Primary Cell Cultures of Patients with Myotonic Dystrophy Type 1.

Autor: Koehorst E; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain., Núñez-Manchón J; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain., Ballester-López A; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain., Almendrote M; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.; Neuromuscular Pathology Unit, Neurology Service, Neuroscience Department, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Spain., Lucente G; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.; Neuromuscular Pathology Unit, Neurology Service, Neuroscience Department, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Spain., Arbex A; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.; Neuromuscular Pathology Unit, Neurology Service, Neuroscience Department, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Spain., Chojnacki J; IrsiCaixa AIDS Research Institute, 08916 Badalona, Spain., Vázquez-Manrique RP; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Laboratory of Molecular, Cellular and Genomic Biomedicine, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.; Joint Unit for Rare Diseases IIS La Fe-CIPF, 46012 Valencia, Spain., Gómez-Escribano AP; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Laboratory of Molecular, Cellular and Genomic Biomedicine, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.; Joint Unit for Rare Diseases IIS La Fe-CIPF, 46012 Valencia, Spain., Pintos-Morell G; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.; Reference Unit for Hereditary Metabolic Disorders (MetabERN), Vall d'Hebron University Hospital, 08035 Barcelona, Spain., Coll-Cantí J; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.; Neuromuscular Pathology Unit, Neurology Service, Neuroscience Department, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Spain., Ramos-Fransi A; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.; Neuromuscular Pathology Unit, Neurology Service, Neuroscience Department, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Spain., Martínez-Piñeiro A; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.; Neuromuscular Pathology Unit, Neurology Service, Neuroscience Department, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Spain., Suelves M; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain., Nogales-Gadea G; Neuromuscular and Neuropediatric Research Group, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Campus Can Ruti, Universitat Autònoma de Barcelona, 08916 Badalona, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.

Publikováno v: Journal of clinical medicine [J Clin Med] 2021 Nov 25; Vol. 10 (23). Date of Electronic Publication: 2021 Nov 25.

Metformin intake associates with better cognitive function in patients with Huntington's disease.

Autor: Hervás D; Department of Biostatistics, Health Research Institute La Fe (Hospital Universitario y Politécnico La Fe), Valencia, Spain., Fornés-Ferrer V; Department of Biostatistics, Health Research Institute La Fe (Hospital Universitario y Politécnico La Fe), Valencia, Spain., Gómez-Escribano AP; Research Group in Molecular, Cellular and Genomic Biomedicine, Health Research Institute La Fe (Hospital Universitario y Politécnico La Fe), Valencia, Spain., Sequedo MD; Research Group in Molecular, Cellular and Genomic Biomedicine, Health Research Institute La Fe (Hospital Universitario y Politécnico La Fe), Valencia, Spain.; CIBER de Enfermedades Raras (CIBERER), Madrid, Spain., Peiró C; Department of Neurology, Hospital Universitario y Politécnico La Fe, Valencia, Spain., Millán JM; Research Group in Molecular, Cellular and Genomic Biomedicine, Health Research Institute La Fe (Hospital Universitario y Politécnico La Fe), Valencia, Spain.; CIBER de Enfermedades Raras (CIBERER), Madrid, Spain., Vázquez-Manrique RP; Research Group in Molecular, Cellular and Genomic Biomedicine, Health Research Institute La Fe (Hospital Universitario y Politécnico La Fe), Valencia, Spain.; CIBER de Enfermedades Raras (CIBERER), Madrid, Spain.

Publikováno v: PloS one [PLoS One] 2017 Jun 20; Vol. 12 (6), pp. e0179283. Date of Electronic Publication: 2017 Jun 20 (Print Publication: 2017).