Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Gérard Mathis"'
Autor:
Pauline Scholler, Damien Nevoltris, Dimitri de Bundel, Simon Bossi, David Moreno-Delgado, Xavier Rovira, Thor C. Møller, Driss El Moustaine, Michaël Mathieu, Emilie Blanc, Heather McLean, Elodie Dupuis, Gérard Mathis, Eric Trinquet, Hervé Daniel, Emmanuel Valjent, Daniel Baty, Patrick Chames, Philippe Rondard, Jean-Philippe Pin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
G protein-coupled receptors are considered promising therapeutic targets. Here, the authors have identified nanobodies, or single-domain llama antibodies, that specifically enhance agonist-induced activity of a type of G protein-coupled receptor, the
Externí odkaz:
https://doaj.org/article/816648732d614ed3bfb0746f18dd9438
Autor:
Suzana P. Vila Nova, Giovannia A. de L. Pereira, Gilberto F. de Sá, Severino Alves Júnior, Hervé Bazin, Hervé Autiero, Gérard Mathis
Publikováno v:
Química Nova, Vol 27, Iss 5, Pp 709-714 (2004)
Externí odkaz:
https://doaj.org/article/49ef8109bfcf45e6bcfc69983eb4e1d6
Autor:
Alexandre Ho-Pun-Cheung, Hervé Bazin, Nadège Gaborit, Christel Larbouret, Patrick Garnero, Eric Assenat, Florence Castan, Caroline Bascoul-Mollevi, Jeanne Ramos, Marc Ychou, André Pèlegrin, Gérard Mathis, Evelyne Lopez-Crapez
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e37065 (2012)
Following the development of targeted therapies against EGFR and HER2, two members of the human epidermal receptor (HER) family of receptor tyrosine kinases, much interest has been focused on their expression in tumors. However, knowing the expressio
Externí odkaz:
https://doaj.org/article/7086be063c3a46c981423774685c6f89
Autor:
Thierry Chardès, André Pèlegrin, Jean-François Prost, Gérard Mathis, Jean-Marc Barret, Philippe Mondon, Marie-Alix Poul, Véronique Garambois, Yassamine Lazrek, Charline Ogier, Christel Larbouret, Olivier Dubreuil, Hervé Bazin, Christophe Le Clorennec
Supplemental Fig.S3. In pancreatic cancer cells, ch9F7-F11-Emb is a negative allosteric modulator of NRG1-mediated signaling. The low-fucose non-NRG1 competing allosteric anti-HER3 antibody ch9F7-F11-Emb inhibits in a dose-dependent manner NRG1-media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca6f44107aaead5130a42c31d8cfc79
https://doi.org/10.1158/1535-7163.22503252.v1
https://doi.org/10.1158/1535-7163.22503252.v1
Autor:
Jean-Pierre Bleuse, Joelle Simony-Lafontaine, Emeline Landas, Alexandre Ho-Pun-Cheung, André Pèlegrin, Evelyne Lopez-Crapez, Gérard Mathis, William Jacot, Florence Boissière-Michot, Jean-François Prost, Caroline Mollevi, Hervé Bazin, Thierry Chardès
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2020, 122 (3), pp.397-404. ⟨10.1038/s41416-019-0670-8⟩
British Journal of Cancer, Cancer Research UK, 2020, 122 (3), pp.397-404. ⟨10.1038/s41416-019-0670-8⟩
BackgroundTriple-negative breast cancer (TNBC) has a worse prognosis compared with other breast cancer subtypes, and biomarkers to identify patients at high risk of recurrence are needed. Here, we investigated the expression of human epidermal recept
Autor:
Daniel Baty, Benjamin Lombard, Damien Nevoltris, Elodie Dupuis, Patrick Chames, Gérard Mathis
Publikováno v:
ACS Nano
ACS Nano, American Chemical Society, 2015, 9 (2), pp.1388-99. ⟨10.1021/nn505752u⟩
ACS Nano, 2015, 9 (2), pp.1388-99. ⟨10.1021/nn505752u⟩
ACS Nano, American Chemical Society, 2015, 9 (2), pp.1388-99. ⟨10.1021/nn505752u⟩
ACS Nano, 2015, 9 (2), pp.1388-99. ⟨10.1021/nn505752u⟩
International audience; The epidermal growth factor receptor (EGFR) is a cell-surface receptor with a single transmembrane domain and tyrosine kinase activity carried by the intracellular domain. This receptor is one of the four members of the ErbB f
Autor:
Véronique Garambois, Philippe Mondon, André Pèlegrin, Olivier Dubreuil, Yassamine Lazrek, Christel Larbouret, Marie-Alix Poul, Gérard Mathis, Jean-Marc Barret, Thierry Chardès, Jean-François Prost, Christophe Le Clorennec, Charline Ogier, Hervé Bazin
Publikováno v:
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2017, 16 (7), pp.1312-1323. ⟨10.1158/1535-7163.MCT-16-0886⟩
Molecular Cancer Therapeutics, American Association for Cancer Research, 2017, 16 (7), pp.1312-1323. ⟨10.1158/1535-7163.MCT-16-0886⟩
Exploratory clinical trials using therapeutic anti-HER3 antibodies strongly suggest that neuregulin (NRG1; HER3 ligand) expression at tumor sites is a predictive biomarker of anti-HER3 antibody efficacy in cancer. We hypothesized that in NRG1-express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50d796db8fd459d5aa6492892a74c7e
https://hal.umontpellier.fr/hal-02434070/document
https://hal.umontpellier.fr/hal-02434070/document
Autor:
Caroline Bascoul-Mollevi, Christel Larbouret, Julie Vallaghe, Herve Bazin, David Azria, Nadège Gaborit, Thierry Chardès, Marie-Alix Poul, Gérard Mathis, Evelyne Crapez, Frédéric Peyrusson, André Pèlegrin
Publikováno v:
Journal of Biological Chemistry. 286:11337-11345
In oncology, simultaneous inhibition of epidermal growth factor receptor (EGFR) and HER2 by monoclonal antibodies (mAbs) is an efficient therapeutic strategy but the underlying mechanisms are not fully understood. Here, we describe a time-resolved fl
Autor:
Gérard Mathis, Jean Grenier, Julien Chevalier, Hervé Bazin, Eric Trinquet, Evelyne Lopez-Crapez
Publikováno v:
Human Mutation. 25:468-475
Single nucleotide primer extension reaction has been widely used in DNA testing, and several detection methods based on this core allelic discrimination have been developed. Most of the reported formats are based on a two step protocol involving firs
Autor:
Suzana P. Vila Nova, Giovannia A. de L. Pereira, Gilberto F. de Sá, Severino Alves Júnior, Hervé Bazin, Hervé Autiero, Gérard Mathis
Publikováno v:
Química Nova, Vol 27, Iss 5, Pp 709-714 (2004)
This work reports on the synthesis, characterization (infrared and hidrogen nmr spectra) and photophysical properties (luminescence spectra and emission quantum yield) of the lanthanide cryptates [LnÌ(bipy)2py(CO2Et) 2]3+ with Ln = Eu3+, Tb3+ or Gd3