Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Gérard Dauphin"'
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2145-2150
The reactivity of hexahydrocarbazolones 3 and 7 in Michael reactions has been studied with several reagents: treatment with acrylonitrile, methyl acrylate and the Mannich base of methyl vinyl ketone leads to 4a-substituted compounds 13–16 in good y
Autor:
Olivier Chavignon, Yves Blache, Florence Fauvelle, Gérard Dauphin, Alain Gueiffier, J. P. Chapat, H. Viols, Jean C. Teulade, Gérard Grassy
Publikováno v:
Journal of Heterocyclic Chemistry. 34:765-771
The synthesis and reactivity of imidazo[1,2-a][1,8]naphthyridines are reported. Electrophilic substitution reactions were studied and the site of the reaction was established with the aid of high-field 1H and 13C nmr spectra. The experimental C-1 pos
Publikováno v:
J. Chem. Soc., Perkin Trans. 2. :1971-1979
13 C and 1H NMR spectra were obtained and totally assigned for all the alkali metal cation complex salts of lasalocid in methanol. Most of the corresponding 1H–1H coupling constants were also accessed. Computational experiments in the solvent metha
Autor:
Martine Sancelme, Gérard Dauphin, Henri Vial, Georges Jeminet, Mohamed Rochdi, Sylvie Gibot, Jean-Gabriel Gourcy, Jacques Guyot, Anne-Marie Delort, Catherine Gumila
Publikováno v:
Journal of Medicinal Chemistry. 39:588-595
Eight derivatives of monensin with a modified C25-C26 moiety were synthesized. Their ionophore properties were studied on human erythrocytes by measuring Na + influx with 23 Na NMR and concomitant K + and H + efflux by potentiometry. Modification of
Publikováno v:
Tetrahedron: Asymmetry. 6:333-336
Poly-γ-benzyl-L-glutamate (PBLG) and dichloromethane form a lyotropic liquid crystal which can be used as solvent for enantiomeric excess analysis of molecules containing several stereogenic centers, through deuterium NMR spectroscopy. All isomers o
Autor:
Y. Pascal, Marc Palma, Rachid Lyazghi, Mostafa Mimouni, Patrice Malfreyt, Gérard Dauphin, Jean Juillard
Publikováno v:
J. Chem. Soc., Perkin Trans. 2. :1939-1947
The successive formation of complexes MA+ and MA2 of alkaline-earth cations M2+ with lasalocid HA is observable in methanol. Knowing the corresponding formation constants, it was possible to access NMR parameters specific to these two types of specie
Publikováno v:
Microchimica Acta. 141:179-181
The objective of this work was to identify the transformation product of nifuroxazide which appeared during stability studies of the drug in hard-capsules using high-performance liquid chromatography. The impurity appears on exposure to light, and te
Publikováno v:
Tetrahedron: Asymmetry. 5:1519-1524
Using a short synthetic protocol, the enantiomerically pure ( + )-E,E title compound was made from (S,S)-diisopropylidenetriglycerol 4 in order to obtain a reference for correlations in this unexplored series. Analogously (S,R)-diisopropylidenetrigly
Autor:
Jacques Guyot, Martine Sancelme, Anne-Marie Delort, Georges Jeminet, M. Rochdi, Gérard Dauphin
Publikováno v:
Bioelectrochemistry and Bioenergetics. 33:83-90
The transporting ability of a new monensin derivative 26-(1,2-diphenyl-1-ethoxy) monensin, highly active against Gram-positive bacteria, was explored with the human erythrocyte model using three technical approaches: 23 Na nuclear magnetic resonance
Autor:
Nelly Morellet, Françoise Vaufrey, Jean Garnier, Valérie Biou, Gérard Dauphin, Jean-Claude Beloeil
Publikováno v:
Magnetic Resonance in Chemistry. 32:83-86
The conformations of the complexes formed by the ionophore nigericin wiht Na + and K + in CDCl 3 solution determined by ROESY NMR and distance geometry computations are in good agreement with the X-ray crystallographic data. The structures with the N