Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Gérard, Molle"'
Publikováno v:
International Journal of Peptide and Protein Research. 45:164-172
Alamethicin, a 20-residue peptaibol, induces voltage-dependent ion channels in lipid bilayers according to the barrel-stave model. A synthetic analogue (L2) in which all Aib were replaced by Leu shows a conductance behaviour similar to alamethicin, b
Autor:
Yannick Bessin, Nathalie Ebran, Virginie Molle, Sylvie Campagna, Nathalie Saint, Gérard Molle
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2008, 411 (1), pp.33-40. ⟨10.1042/BJ20070801⟩
Biochemical Journal, Portland Press, 2008, 411 (1), pp.33-40. ⟨10.1042/BJ20070801⟩
The epidermis of fish is covered with a layer of mucus, which contributes to the defence of the species against parasites, bacteria and fungi. We have previously extracted glycoproteins from various mucus samples from fish and have shown that they pr
Publikováno v:
Biochemistry. 46:1771-1778
Piscidin, an antibacterial peptide isolated from the mast cells of striped bass, has potent antimicrobial activity against a broad spectrum of pathogens in vitro. We investigated the mechanism of action of this 22-residue cationic peptide by carrying
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1667:148-156
Ceratotoxins are α-helical cationic peptides isolated from the medfly Ceratitis capitata. These amphipathic peptides were found to display strong antibacterial activity and weak hemolytic activity. When reconstituted into planar lipid bilayers, cera
Publikováno v:
Biophysical Journal. 86:248-253
Alamethicin, a 20 residue-long peptaibol remains a favorite high voltage-dependent channel-forming peptide. However, the structural significance of its abundant noncoded residues (α-methylalanine or Aib) for its ion channel activity remains unknown,
Autor:
M. Barthelemy, Anne-Marie Pons, Bénédicte Boscher, Christophe Goulard, Jean Peduzzi, Gérard Molle, Xavier Thomas, Sylvie Rebuffat, Lucienne Letellier, Yannick Bessin, Monica Santamaria, Delphine Destoumieux-Garzón
Publikováno v:
Molecular Microbiology. 49:1031-1041
The mechanism of action of microcin E492 (MccE492) was investigated for the first time in live bacteria. MccE492 was expressed and purified to homogeneity through an optimized large-scale procedure. Highly purified MccE492 showed potent antibacterial
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:1555-1559
Two clinical strains of Enterobacter aerogenes that exhibited phenotypes of multiresistance to β-lactam antibiotics, fluoroquinolones, chloramphenicol, tetracycline, and kanamycin were investigated. Both strains showed a porin pattern different from
Autor:
Jérôme BREDIN, Nathalie SAINT, Monique MALLÉA, Emmanuelle DÉ, Gérard MOLLE, Jean-Marie PAGÈS, Valérie SIMONET
Publikováno v:
Biochemical Journal. 363:521-528
The Escherichia coli OmpF pore is governed by an internal constriction consisting of the negatively charged loop 3 folded into the lumen and the positively charged barrel wall located on the opposite side across the pore, ‘anti-loop 3'. To investig
Autor:
Monique Malléa, Emmanuelle Dé, Michel Jaquinod, Nathalie Saint, Jean-Marie Pagès, Gérard Molle, Arnaud Baslé
Publikováno v:
Molecular Microbiology. 41:189-198
In Enterobacter aerogenes, multidrug resistance involves a decrease in outer membrane permeability associated with changes in an as yet uncharacterized porin. We purified the major porin from the wild-type strain and a resistant strain. We characteri
Publikováno v:
BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2001, pp.217-222
BBA-Biochimica et Biophysica Acta, Elsevier, 2001, pp.217-222
Component PP3 is a phosphoglycoprotein isolated from bovine milk with unknown biological function, which displays in its C-terminal region a basic amphipathic α-helix, a feature often involved in membrane association. According to that, the behaviou