Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Gérard, Keith"'
Autor:
Stepánka Vanácová, Jeannette Wolf, Georges Martin, Diana Blank, Sabine Dettwiler, Arno Friedlein, Hanno Langen, Gérard Keith, Walter Keller
Publikováno v:
PLoS Biology, Vol 3, Iss 6, p e189 (2005)
Eukaryotic cells contain several unconventional poly(A) polymerases in addition to the canonical enzymes responsible for the synthesis of poly(A) tails of nuclear messenger RNA precursors. The yeast protein Trf4p has been implicated in a quality cont
Externí odkaz:
https://doaj.org/article/30a6f292345f4fb89edeac397c43fc02
Autor:
Florian Eberle, Volker A. Erdmann, Alexander H. Dalpke, Walter M. Holmes, Gérard Keith, Steffen Kaiser, Mathias Sprinzl, Guillaume Bec, Tatjana Eigenbrod, Mariel-Esther Eberle, Flavia Botschen, Mark Helm, Katharina Rimbach, Stefanie Gehrig
Publikováno v:
The Journal of Experimental Medicine
2′-O-methylation of guanosine 18 is a naturally occurring tRNA modification that can suppress immune TLR7 responses.
Naturally occurring nucleotide modifications within RNA have been proposed to be structural determinants for innate immune rec
Naturally occurring nucleotide modifications within RNA have been proposed to be structural determinants for innate immune rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cdb9e3cd01947d424707adee116d93
http://europepmc.org/articles/PMC3280868
http://europepmc.org/articles/PMC3280868
Autor:
Bertrand Rihn, G. Morel, Laurent Gate, Catherine Champmartin, Marie Claire Bottin, Gérard Keith, Jean Claude Micillino, Lucie Ayi-Fanou, Richard Wrobel, Hervé Nunge, Stéphane Binet, Aurélie Martin, Monhoven Nathalie
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2006, 596 (1-2), pp.91-105. ⟨10.1016/j.mrfmmm.2005.12.005⟩
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2006, 596 (1-2), pp.91-105. ⟨10.1016/j.mrfmmm.2005.12.005⟩
Road paving workers are exposed to bitumen fumes (CAS No. 8052-42-4), a complex mixture of volatile compounds and particles containing carcinogenic and non-carcinogenic polycyclic aromatic hydrocarbons. However, epidemiological and experimental anima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5218314217348dbfc0cdb8839c3f56e2
https://doi.org/10.1016/j.mrfmmm.2005.12.005
https://doi.org/10.1016/j.mrfmmm.2005.12.005
Autor:
Daniel Y. Dubois, Daniel Kern, Valérie Campanacci, Jacques Lapointe, Christian Cambillau, Hubert Dominique Becker, Mickaël Blaise, Richard Giegé, Gérard Keith
Publikováno v:
Dubois, D Y, Blaise, M, Becker, H D, Campanacci, V, Keith, G, Giege, R, Cambillau, C, Lapointe, J & Kern, D 2004, ' An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp. ', Proceeding of the National Academy of Sciences USA .
The product of the Escherichia coli yadB gene is homologous to the N-terminal part of bacterial glutamyl-tRNA synthetases (GluRSs), including the Rossmann fold with the acceptor-binding domain and the stem-contact fold. This GluRS-like protein, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553cc4cb5f21f889c163909187acea6c
https://doi.org/10.1073/pnas.0401634101
https://doi.org/10.1073/pnas.0401634101
Publikováno v:
Journal of Chromatography B. 801:237-247
Three queuosine derivatives (Q-derivatives) have been found at position 34 of four mammalian so-called Q-tRNAs: queuosine (Q) in tRNA(Asn) and tRNA(His), mannosyl-queuosine (manQ) in tRNA(Asp), and galactosyl-queuosine (galQ) in tRNA(Tyr). An analyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56630c297d97408ce285ede30b6da7ea
https://doi.org/10.1016/j.jchromb.2003.11.022
https://doi.org/10.1016/j.jchromb.2003.11.022
Autor:
Béatrice Lannes, Marie-Claire Bottin, Jean-Pierre Bellocq, Gérard Keith, Agnès Neuville, Bertrand H. Rihn, Steve Mohr
Publikováno v:
Biochimie. 86:13-19
The studies of molecular alterations in tumor cells with microarrays are often hampered by inherent tissue heterogeneity. The emergence of Laser Capture Microdissection (LCM) allowed us to overcome this challenge since it gives selective access to ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96378ebab19bfccb43d70c787466102
https://doi.org/10.1016/j.biochi.2003.11.008
https://doi.org/10.1016/j.biochi.2003.11.008
Publikováno v:
tRNA
This chapter talks about primary, secondary, and tertiary structures of tRNAs. What is striking about the tRNA molecule is its extreme variability in primary and secondary structures. Every single invariant or semi-invariant position has numerous exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e7b7499a9eb740c8b4e30dd98fecf11
https://doi.org/10.1128/9781555818333.ch8
https://doi.org/10.1128/9781555818333.ch8
Autor:
Domenica Carnicelli, Maurizio Brigotti, Simona Rizzi, Lucio Montanaro, Gérard Keith, Simonetta Sperti
Publikováno v:
FEBS Letters. 492:238-241
Wild-type bovine and yeast tRNATrp are efficiently aminoacylated by tryptophanyl-tRNA synthetase both from beef and from yeast. Upon loss of modified bases in the synthetic transcripts, mammalian tRNATrp retains the double recognition by the two synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6398accc5eeaa24611cbec967b6330fd
https://doi.org/10.1016/s0014-5793(01)02261-x
https://doi.org/10.1016/s0014-5793(01)02261-x
Autor:
Aléodjrodo Edorh, Gérard Keith, Nathalie Monhoven, Marie-Claire Bottin, Bertrand H. Rihn, Raphaël Rouget, C. Coulais, Wlodzimierz Baranowski
Publikováno v:
Environmental and Molecular Mutagenesis. 36:266-273
Transgenic mice provide a unique tool for studying the tissue specificity and mutagenic potential of chemicals. Because 3-methylcholanthrene (3MC) was found mutagenic in bacteria, clastogenic in bone marrow, and induces DNA adducts in animals, we wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b3d05f1e15e1d766286518f3bec5fc
https://doi.org/10.1002/1098-2280(2000)36:4<266::aid-em2>3.0.co
https://doi.org/10.1002/1098-2280(2000)36:4<266::aid-em2>3.0.co
Autor:
Gérard Keith, Victoria M. Perreau, W. Mike Holmes, Mick F. Tuite, Anna Przykorska, Manuel A. S. Santos
Publikováno v:
Journal of Molecular Biology. 293:1039-1053
In many Candida species, the leucine CUG codon is decoded by a tRNA with two unusual properties: it is a ser-tRNA and, uniquely, has guanosine at position 33 (G33). Using a combination of enzymatic (V1 RNase, RnI nuclease) and chemical (Pb2+, imidazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ba0af4550b1fc39b08889a301b49fd4
https://doi.org/10.1006/jmbi.1999.3209
https://doi.org/10.1006/jmbi.1999.3209