Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Gérard, Chassaing"'
Autor:
Julia Fath, Franck Brouillard, Alexandre Cabaye, Damien Claverie, Philippe Nuss, Victoria Poillerat, Serge Chwetzoff, Tahar Bouceba, Elodie Bouvier, Myriam Salameh, Jenny Molet, Aïda Padilla-Ferrer, Philippe Couvert, Francine Acher, Marie-Pierre Golinelli-Cohen, Gérard Chassaing, Germain Trugnan, Christophe Bernard, Jean-Jacques Benoliel, Chrystel Becker
In addition to its well-known receptor-mediated function in cell survival, differentiation and growth, we report that the extracellular brain-derived neurotrophic factor (BDNF) also controls the intracellular KEAP1-NRF2 cytoprotective system by a rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aba513608c2627c17b99ec1ae34a0787
https://doi.org/10.1101/2022.08.23.504973
https://doi.org/10.1101/2022.08.23.504973
Autor:
Céline Cordier, Fatima Boutimah, Mathilde Bourdeloux, Florian Dupuy, Elisabeth Met, Patrizia Alberti, François Loll, Gérard Chassaing, Fabienne Burlina, Tula Ester Saison-Behmoaras
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104999 (2014)
Peptide nucleic acids (PNAs) are very attractive antisense and antigene agents, but these molecules are not passively taken into cells. Here, using a functional cell assay and fluorescent-based methods, we investigated cell uptake and antisense activ
Externí odkaz:
https://doaj.org/article/e804fa2583b54399bed2c944adf25005
Autor:
Antonin Lamazière, Claude Wolf, Olivier Lambert, Gérard Chassaing, Germain Trugnan, Jesus Ayala-Sanmartin
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1938 (2008)
BACKGROUND:Protein membrane transduction domains that are able to cross the plasma membrane are present in several transcription factors, such as the homeodomain proteins and the viral proteins such as Tat of HIV-1. Their discovery resulted in both n
Externí odkaz:
https://doaj.org/article/926a9c686db64b6a80d6adc79aff18bb
Autor:
Antonin Lamazière, Fabienne Burlina, Claude Wolf, Gérard Chassaing, Germain Trugnan, Jesus Ayala-Sanmartin
Publikováno v:
PLoS ONE, Vol 2, Iss 2, p e201 (2007)
BACKGROUND:Basic cell-penetrating peptides are potential vectors for therapeutic molecules and display antimicrobial activity. The peptide-membrane contact is the first step of the sequential processes leading to peptide internalization and cell acti
Externí odkaz:
https://doaj.org/article/4993411a1b244137b633c2255159016d
Autor:
Sandrine Sagan, Isabel D. Alves, Chen-Yu Jiao, Gérard Chassaing, Emmanuelle Sachon, Gérard Bolbach
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2017, 56 (28), pp.8226-8230. ⟨10.1002/anie.201703465⟩
Angewandte Chemie International Edition, 2017, 56 (28), pp.8226-8230. ⟨10.1002/anie.201703465⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2017, 56 (28), pp.8226-8230. ⟨10.1002/anie.201703465⟩
Angewandte Chemie International Edition, 2017, 56 (28), pp.8226-8230. ⟨10.1002/anie.201703465⟩
International audience; Penetratin (RQIKIWFQNRRMKWKK) enters cells by different mechanisms, including membrane translocation, thus implying that the peptide interacts with the lipid bilayer. Penetratin also crosses the membrane of artificial vesicles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b6340f64a541a1e4d2ea1f80aae7c6
https://doi.org/10.1002/anie.201703465
https://doi.org/10.1002/anie.201703465
Autor:
Simon Gonzalez, Alfonso Carotenuto, Sabrina Kellouche, Paolo Rovero, Gérard Chassaing, Florian Gallier, Franck Carreiras, Ettore Novellino, Nadège Lubin-Germain, Jacques Uziel
Publikováno v:
Biochimica et Biophysica Acta:Biomembranes
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2019, 1861 (1), pp.50-61. ⟨10.1016/j.bbamem.2018.10.011⟩
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2019, 1861 (1), pp.50-61. ⟨10.1016/j.bbamem.2018.10.011⟩
International audience; Over the past decades, membranotropic peptides such as positively charged cell-penetrating peptides (CPPs) or amphipathic antimicrobial peptides (AMPs) have received increasing interest in order to improve therapeutic agent ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574535c6e767feb0e3ad5623f682cde6
http://hdl.handle.net/11588/769172
http://hdl.handle.net/11588/769172
Autor:
Margherita Di Pisa, Fabienne Burlina, Christelle Mansuy, Gérard Chassaing, Jean-Marie Swiecicki, Solange Lavielle, Pascaline Lécorché
Publikováno v:
Biopolymers. 104:533-543
The internalization of cell-penetrating peptides (CPPs) into liposomes (large unilamellar vesicles, LUVs) was studied with a rapid and robust procedure based on the quenching of a small fluorescent probe, 7-nitrobenz-2-oxa-1,3-diazole (NBD). Quenchin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42776841f3012cad2c264bb19283823e
https://doi.org/10.1002/bip.22652
https://doi.org/10.1002/bip.22652
Autor:
Olivier Lequin, Amina Benchohra, Jean-Maurice Mallet, Christelle Mansuy, Nicolas Auberger, Gérard Chassaing, Joussef Hayek, Anna Maria Papini, Solange Lavielle, Maud Larregola, Francesco Lolli, Margherita Di Pisa, Paolo Rovero, Feliciana Real Fernández, Giada Rossi
Publikováno v:
Biopolymers. 104:560-576
Antibody detection in autoimmune disorders, such as multiple sclerosis (MS) and Rett syndrome (RTT) can be achieved more efficiently using synthetic peptides. The previously developed synthetic antigenic probe CSF114(Glc), a type I' beta-turn N-gluco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9b0d383de0b755216174bda1ed389c6
https://doi.org/10.1002/bip.22677
https://doi.org/10.1002/bip.22677
Publikováno v:
Journal of Peptide Science. 21:356-369
Cell-penetrating peptides (CPPs) are short sequences often rich in cationic residues with the remarkable ability to cross cell membranes. In the past 20 years, CPPs have gained wide interest and have found numerous applications in the delivery of bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8983a1794955a27f5e864fcd748319f
https://doi.org/10.1002/psc.2755
https://doi.org/10.1002/psc.2755
Autor:
Fabienne Burlina, Christelle Mansuy, F. Lippi, Germain Trugnan, S. Chwetzoff, Solange Lavielle, Jean-Marie Swiecicki, Gérard Chassaing, M. Di Pisa
Publikováno v:
Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2015, 51 (78), pp.14656-14659. ⟨10.1039/c5cc06116d⟩
Chemical Communications, 2015, 51 (78), pp.14656-14659. ⟨10.1039/c5cc06116d⟩
Chemical Communications, Royal Society of Chemistry, 2015, 51 (78), pp.14656-14659. ⟨10.1039/c5cc06116d⟩
Chemical Communications, 2015, 51 (78), pp.14656-14659. ⟨10.1039/c5cc06116d⟩
International audience; The recurring issue with cell penetrating peptides is how to increase direct translocation vs. endocytosis, to avoid premature degradation. Acylation by a cis unsaturated chain (C22:6) of a short cationic peptide provides a ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b1414c856c13ae7b766dd91af929b5
https://doi.org/10.1039/c5cc06116d
https://doi.org/10.1039/c5cc06116d