Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Géraldine Seydoux"'
Autor:
Sylvia Nkombo Nkoula, Griselda Velez-Aguilera, Batool Ossareh-Nazari, Lucie Van Hove, Cristina Ayuso, Véronique Legros, Guillaume Chevreux, Laura Thomas, Géraldine Seydoux, Peter Askjaer, Lionel Pintard
Publikováno v:
bioRxiv
The nuclear envelope, which protects and organizes the interphase genome, is dismantled during mitosis. In theC. eleganszygote, nuclear envelope breakdown (NEBD) of the parental pronuclei is spatially and temporally regulated during mitosis to promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7bbb8da18173fdda4744e2781a1d4c
https://europepmc.org/articles/PMC9980100/
https://europepmc.org/articles/PMC9980100/
Autor:
Roger S. Zou, Momcilo Gavrilov, Yang Liu, Dominique Rasoloson, Madison Conte, Justin Hardick, Leo Shen, Siqi Chen, Andrew Pekosz, Geraldine Seydoux, Yukari C. Manabe, Taekjip Ha
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
A new method, SENTINEL, improves the specificity of nucleic acid target sequence identification via a combination of isothermal amplification and sequence-specific DNA endonucleases. The method can discriminate single base-pair differences and takes
Externí odkaz:
https://doaj.org/article/b7f8b4a095934bac9fed77d6c3ba3267
Publikováno v:
eLife, Vol 10 (2021)
Germ granules are protein-RNA condensates that segregate with the embryonic germline. In Caenorhabditis elegans embryos, germ (P) granule assembly requires MEG-3, an intrinsically disordered protein that forms RNA-rich condensates on the surface of P
Externí odkaz:
https://doaj.org/article/b9385f04abef4019b8667701e6cb0f3a
Autor:
Syed Usman Enam, Boris Zinshteyn, Daniel H Goldman, Madeline Cassani, Nathan M Livingston, Geraldine Seydoux, Rachel Green
Publikováno v:
eLife, Vol 9 (2020)
Puromycin is a tyrosyl-tRNA mimic that blocks translation by labeling and releasing elongating polypeptide chains from translating ribosomes. Puromycin has been used in molecular biology research for decades as a translation inhibitor. The developmen
Externí odkaz:
https://doaj.org/article/4f34ce7e063048d9bde53f7974f89f11
Publikováno v:
eLife, Vol 9 (2020)
RNA granules are protein/RNA condensates. How specific mRNAs are recruited to cytoplasmic RNA granules is not known. Here, we characterize the transcriptome and assembly of P granules, RNA granules in the C. elegans germ plasm. We find that P granule
Externí odkaz:
https://doaj.org/article/9e4b10e3533e4857b1b554528c08c9fe
Publikováno v:
eLife, Vol 6 (2017)
Nanos RNA-binding proteins are required for germline development in metazoans, but the underlying mechanisms remain poorly understood. We have profiled the transcriptome of primordial germ cells (PGCs) lacking the nanos homologs nos-1 and nos-2 in C.
Externí odkaz:
https://doaj.org/article/33522224c6064703acae219b60f7ec55
Publikováno v:
eLife, Vol 5 (2016)
RNA granules are non-membrane bound cellular compartments that contain RNA and RNA binding proteins. The molecular mechanisms that regulate the spatial distribution of RNA granules in cells are poorly understood. During polarization of the C. elegans
Externí odkaz:
https://doaj.org/article/bf691ea01ae746b691c582e6b66ec743
Autor:
Jennifer T Wang, Jarrett Smith, Bi-Chang Chen, Helen Schmidt, Dominique Rasoloson, Alexandre Paix, Bramwell G Lambrus, Deepika Calidas, Eric Betzig, Geraldine Seydoux
Publikováno v:
eLife, Vol 3 (2014)
RNA granules have been likened to liquid droplets whose dynamics depend on the controlled dissolution and condensation of internal components. The molecules and reactions that drive these dynamics in vivo are not well understood. In this study, we pr
Externí odkaz:
https://doaj.org/article/84528ffd85fb4174a408bf373b06bfb9
Autor:
Myon-Hee Lee, Brad Hook, Guangjin Pan, Aaron M Kershner, Christopher Merritt, Geraldine Seydoux, James A Thomson, Marvin Wickens, Judith Kimble
Publikováno v:
PLoS Genetics, Vol 3, Iss 12, p e233 (2007)
Mitogen-activated protein kinase (MAPK) and PUF (for Pumilio and FBF [fem-3 binding factor]) RNA-binding proteins control many cellular processes critical for animal development and tissue homeostasis. In the present work, we report that PUF proteins
Externí odkaz:
https://doaj.org/article/43042592df8f45059eda03519633e844