Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Géraldine Pron"'
Autor:
Nawel Mahrour, Géraldine Pron, B. Poddevin, Stéphane Orlowski, Omar Tounekti, Lluis M. Mir, Jean Belehradek
Publikováno v:
Biochemical pharmacology. 57(1)
Bleomycin (BLM) does not diffuse through the plasma membrane but nevertheless displays cytotoxic activity due to DNA break generation. The aim of the study was to describe the mechanism of BLM internalisation. We previously provided evidence for the
Publikováno v:
Biochemical pharmacology. 48(2)
The authors have recently shown the existence of bleomycin (BLM)-binding sites at the surface of DC-3F cells. In order to study the involvement of these sites in the sensitivity of the cells to bleomycin several BLM-resistant cell lines from DC-3F ce
Publikováno v:
Biochimica et biophysica acta. 1190(1)
Using cells in suspension, electropermeabilization is a technique extensively used to transfect living cells or to introduce a variety of compounds inside the cells. Here we demonstrate the reality of the tissue electropermeabilization using qualitat
Publikováno v:
Biochemical and biophysical research communications. 194(1)
In this paper, the association of radiolabelled bleomycin on the plasma membrane of DC-3F cells is shown to be saturable, displaying classical features of a ligand-receptor binding. This association corresponds to the presence of 140,000 to 400,000 b