Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gérald Perret"'
Autor:
Emilie Jacque, Claire Chottin, Daphné Laubreton, Michel Nogre, Cécile Ferret, Sandrine de Marcos, Linda Baptista, Carole Drajac, Philippe Mondon, Christophe De Romeuf, Marie-Anne Rameix-Welti, Jean-François Eléouët, Sami Chtourou, Sabine Riffault, Gérald Perret, Delphyne Descamps
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Respiratory syncytial virus (RSV) is a public health concern that causes acute lower respiratory tract infection. So far, no vaccine candidate under development has reached the market and the only licensed product to prevent RSV infection in at-risk
Externí odkaz:
https://doaj.org/article/60e6235c03cb48fa83a88edd7da361a6
Publikováno v:
Pharmaceuticals, Vol 9, Iss 4, p 76 (2016)
Aptamers are identified through an iterative process of evolutionary selection starting from a random pool containing billions of sequences. Simultaneously to the amplification of high-affinity candidates, the diversity in the pool is exponentially r
Externí odkaz:
https://doaj.org/article/6b402d6157c84699abe10cdb3a70ace6
Autor:
Linda Baptista, Nathalie Heuzé-Vourc'h, Renaud Respaud, Laurent Vecellio, Gérald Perret, Philippe Duquenne, Elsa Bodier-Montagutelli
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2020, 152, pp.23-34. ⟨10.1016/j.ejpb.2020.04.006⟩
European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2020, ⟨10.1016/j.ejpb.2020.04.006⟩
European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2020, 152, pp.23-34. ⟨10.1016/j.ejpb.2020.04.006⟩
European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2020, ⟨10.1016/j.ejpb.2020.04.006⟩
International audience; Inhaled protein therapeutics meet a growing interest for the treatment of respiratory diseases. In liquid aerosols, proteins face stresses that may generate instabilities, such as physicochemical denaturations, aggregation and
Publikováno v:
Journal of Separation Science. 38:2559-2572
Affinity chromatography separations of proteins call for highly specific ligands. Antibodies are the most obvious approach; however, except for specific situations, technical and economic reasons are arguments against this choice especially for prepa
Autor:
Gérald Perret, Egisto Boschetti
Publikováno v:
Biochimie. 145
The present review deals with the place of single chain oligonucleotide ligands (aptamers) in affinity chromatography applied to proteins. Aptamers are not the only affinity ligands available but they represent an emerging and highly promising route
Autor:
Agnès Cibiel, Nicolas Bihoreau, Frédéric Ducongé, Cynthia Forier, Sami Chtourou, Mohamed Ouhammouch, Gérald Perret, Michel Nogre, Patrick Santambien, Egisto Boschetti, Michel Tellier, Damien Bataille
Publikováno v:
Journal of Chromatography A.
Nucleic acid aptamers are promising ligands for analytical and preparative-scale affinity chromatography applications. However, a full industrial exploitation requires that aptamer-grafted chromatography media provide a number of high technical stand
Publikováno v:
Blood. 122:3583-3583
Congenital Hemophilia A and B treatment may be complicated by the development of inhibitors to the coagulation factors used in the replacement therapies. In such cases factor replacement becomes ineffective, and use of a bypassing agent is needed to