Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Gérémy Sannier"'
Autor:
Jonathan Richard, Gérémy Sannier, Li Zhu, Jérémie Prévost, Lorie Marchitto, Mehdi Benlarbi, Guillaume Beaudoin-Bussières, Hongil Kim, Yaping Sun, Debashree Chatterjee, Halima Medjahed, Catherine Bourassa, Gloria-Gabrielle Delgado, Mathieu Dubé, Frank Kirchhoff, Beatrice H. Hahn, Priti Kumar, Daniel E. Kaufmann, Andrés Finzi
Publikováno v:
mBio, Vol 15, Iss 11 (2024)
ABSTRACT HIV-1 envelope glycoprotein (Env) conformation substantially impacts antibody-dependent cellular cytotoxicity (ADCC). Envs from primary HIV-1 isolates adopt a prefusion “closed” conformation, which is targeted by broadly neutralizing ant
Externí odkaz:
https://doaj.org/article/e5ef3dc6caf5435fa447f314f7bf4a25
Autor:
Elsa Brunet-Ratnasingham, Sacha Morin, Haley E. Randolph, Marjorie Labrecque, Justin Bélair, Raphaël Lima-Barbosa, Amélie Pagliuzza, Lorie Marchitto, Michael Hultström, Julia Niessl, Rose Cloutier, Alina M. Sreng Flores, Nathalie Brassard, Mehdi Benlarbi, Jérémie Prévost, Shilei Ding, Sai Priya Anand, Gérémy Sannier, Amanda Marks, Dick Wågsäter, Eric Bareke, Hugo Zeberg, Miklos Lipcsey, Robert Frithiof, Anders Larsson, Sirui Zhou, Tomoko Nakanishi, David Morrison, Dani Vezina, Catherine Bourassa, Gabrielle Gendron-Lepage, Halima Medjahed, Floriane Point, Jonathan Richard, Catherine Larochelle, Alexandre Prat, Janet L. Cunningham, Nathalie Arbour, Madeleine Durand, J. Brent Richards, Kevin Moon, Nicolas Chomont, Andrés Finzi, Martine Tétreault, Luis Barreiro, Guy Wolf, Daniel E. Kaufmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Plasma RNAemia, delayed antibody responses and inflammation predict COVID-19 outcomes, but the mechanisms underlying these immunovirological patterns are poorly understood. We profile 782 longitudinal plasma samples from 318 hospitalized pat
Externí odkaz:
https://doaj.org/article/59f2aa4758444b718331711ce163fcf7
Autor:
Alexandre Nicolas, Gérémy Sannier, Mathieu Dubé, Manon Nayrac, Alexandra Tauzin, Mark M. Painter, Rishi R. Goel, Mélanie Laporte, Gabrielle Gendron-Lepage, Halima Medjahed, Justine C. Williams, Nathalie Brassard, Julia Niessl, Laurie Gokool, Chantal Morrisseau, Pascale Arlotto, Cécile Tremblay, Valérie Martel-Laferrière, Andrés Finzi, Allison R. Greenplate, E. John Wherry, Daniel E. Kaufmann
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105904- (2023)
Summary: Spacing the first two doses of SARS-CoV-2 mRNA vaccines beyond 3–4 weeks raised initial concerns about vaccine efficacy. While studies have since shown that long-interval regimens induce robust antibody responses, their impact on B and T c
Externí odkaz:
https://doaj.org/article/cb87a511664f4979acf3c0bb560c1dde
Autor:
Julia Niessl, Amy E. Baxter, Antigoni Morou, Elsa Brunet-Ratnasingham, Gérémy Sannier, Gabrielle Gendron-Lepage, Jonathan Richard, Gloria-Gabrielle Delgado, Nathalie Brassard, Isabelle Turcotte, Rémi Fromentin, Nicole F. Bernard, Nicolas Chomont, Jean-Pierre Routy, Mathieu Dubé, Andrés Finzi, Daniel E. Kaufmann
Publikováno v:
EBioMedicine, Vol 54, Iss , Pp - (2020)
Background: Untreated HIV infection leads to alterations in HIV-specific CD4+ T cells including increased expression of co-inhibitory receptors (IRs) and skewing toward a T follicular helper cell (Tfh) signature. However, which changes are maintained
Externí odkaz:
https://doaj.org/article/b9c632e219604240ae02b8e6379da988
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The need for definitive answers probably explains our natural tendency to seek simplicity. The reductionist “bulk” approach, in which a mean behavior is attributed to a heterogeneous cell population, fulfills this need by considerably helping the
Externí odkaz:
https://doaj.org/article/05a8051a85394443afd400b5e282acf0
Autor:
Gérémy Sannier, Alexandre Nicolas, Mathieu Dubé, Lorie Marchitto, Manon Nayrac, Olivier Tastet, Alexandra Tauzin, Raphaël Lima-Barbosa, Mélanie Laporte, Rose Cloutier, Alina Sreng Flores, Marianne Boutin, Shang Yu Gong, Mehdi Benlarbi, Shilei Ding, Catherine Bourassa, Gabrielle Gendron-Lepage, Halima Medjahed, Guillaume Goyette, Nathalie Brassard, Gloria-Gabrielle Ortega-Delgado, Julia Niessl, Laurie Gokool, Chantal Morrisseau, Pascale Arlotto, Norka Rios, Cécile Tremblay, Valérie Martel-Laferrière, Alexandre Prat, Justin Bélair, William Beaubien-Souligny, Rémi Goupil, Annie-Claire Nadeau-Fredette, Caroline Lamarche, Andrés Finzi, Rita S. Suri, Daniel E. Kaufmann
Cellular immune defects associated with suboptimal responses to SARS-CoV-2 mRNA vaccination in people receiving hemodialysis (HD) are poorly understood. We longitudinally analyzed antibody, B cell, CD4+ and CD8+ T cell vaccine responses in 27 HD pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a632be7466520b808ebf6ca712c2aad
https://doi.org/10.1101/2022.09.05.506622
https://doi.org/10.1101/2022.09.05.506622
Autor:
Alexandre Nicolas, Gérémy Sannier, Mathieu Dubé, Manon Nayrac, Mark M. Painter, Rishi R. Goel, Mélanie Laporte, Halima Medjahed, Justine C. Williams, Nathalie Brassard, Julia Niessl, Laurie Gokool, Chantal Morrisseau, Pascale Arlotto, Cécile Tremblay, Valérie Martel-Laferrière, Andrés Finzi, Allison R. Greenplate, E. John Wherry, Daniel E. Kaufmann
SUMMARYSpacing the first two doses of SARS-CoV-2 mRNA vaccines beyond 3-4 weeks raised initial concerns about vaccine efficacy. While studies have since shown that long-interval regimens induce robust antibody responses, their impact on B and T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f43ad386718a907b6def47c102af1f
https://doi.org/10.1101/2022.08.03.502672
https://doi.org/10.1101/2022.08.03.502672
Autor:
Gérémy Sannier, Alexandre Nicolas, Mathieu Dubé, Lorie Marchitto, Manon Nayrac, Olivier Tastet, Debashree Chatterjee, Alexandra Tauzin, Raphaël Lima-Barbosa, Mélanie Laporte, Rose Cloutier, Alina M. Sreng Flores, Marianne Boutin, Shang Yu Gong, Mehdi Benlarbi, Shilei Ding, Catherine Bourassa, Gabrielle Gendron-Lepage, Halima Medjahed, Guillaume Goyette, Nathalie Brassard, Gloria-Gabrielle Delgado, Julia Niessl, Laurie Gokool, Chantal Morrisseau, Pascale Arlotto, Norka Rios, Cécile Tremblay, Valérie Martel-Laferrière, Alexandre Prat, Justin Bélair, William Beaubien-Souligny, Rémi Goupil, Annie-Claire Nadeau-Fredette, Caroline Lamarche, Andrés Finzi, Rita S. Suri, Daniel E. Kaufmann
Publikováno v:
Cell Reports Medicine. 4:100955
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5de31280ae3d3ae85cbe11aeb1f4998
https://doi.org/10.1016/j.xcrm.2023.100955
https://doi.org/10.1016/j.xcrm.2023.100955
Autor:
Manon Nayrac, Mathieu Dubé, Gérémy Sannier, Alexandre Nicolas, Lorie Marchitto, Olivier Tastet, Alexandra Tauzin, Nathalie Brassard, Raphaël Lima-Barbosa, Guillaume Beaudoin-Bussières, Dani Vézina, Shang Yu Gong, Mehdi Benlarbi, Romain Gasser, Annemarie Laumaea, Jérémie Prévost, Catherine Bourassa, Gabrielle Gendron-Lepage, Halima Medjahed, Guillaume Goyette, Gloria-Gabrielle Ortega-Delgado, Mélanie Laporte, Julia Niessl, Laurie Gokool, Chantal Morrisseau, Pascale Arlotto, Jonathan Richard, Justin Bélair, Alexandre Prat, Cécile Tremblay, Valérie Martel-Laferrière, Andrés Finzi, Daniel E. Kaufmann
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
SUMMARYSpacing of the BNT162b2 mRNA doses beyond 3 weeks raised concerns about vaccine efficacy. We longitudinally analyzed B cell, T cell and humoral responses to two BNT162b2 mRNA doses administered 16 weeks apart in 53 SARS-CoV-2 naïve and previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbd732f6f63f165e9f17576a8be5389
https://doi.org/10.2139/ssrn.4003710
https://doi.org/10.2139/ssrn.4003710
Autor:
Alexandre Nicolas, Josée Perreault, Lauriane Nault, Daniel Kaufmann, Guillaume Beaudoin-Bussières, Yuxia Bo, Renée Bazin, Marceline Côté, Romain Gasser, Ralf Duerr, Nicholas Brousseau, Debashree Chatterjee, Manon Nayrac, Jérémie Prévost, Lorie Marchitto, Mehdi Benlarbi, Giulia Marchetti, Gérémy Sannier, Gaston De Serres, Cécile Tremblay, Guillaume Goyette, Gabrielle Gendron-Lepage, Jonathan Richard, Mathieu Dubé, Halima Medjahed, Pascale Arlotto, Catherine Bourassa, Valérie Martel-Laferrière, Marianne Boutin, Annemarie Laumaea, Andrés Finzi, Roberta Rovito, Shang Yu Gong, Dani Vézina, Alexandra Tauzin, Laurie Gokool, Chantal Morrisseau
Publikováno v:
Cell Host & Microbe
The standard regimen of the BNT162b2 mRNA vaccine for SARS-CoV-2 includes two doses administered three weeks apart. However, some public health authorities spaced these doses, raising questions about efficacy. We analyzed longitudinal humoral respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f08ce76bc87042220f9d35e6b92664
https://pubmed.ncbi.nlm.nih.gov/34953513
https://pubmed.ncbi.nlm.nih.gov/34953513