Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gábor Halmos"'
Autor:
Orsolya Feró, Dóra Varga, Éva Nagy, Zsolt Karányi, Éva Sipos, József Engelhardt, Nóra Török, István Balogh, Borbála Vető, István Likó, Ábel Fóthi, Zoltán Szabó, Gábor Halmos, László Vécsei, Tamás Arányi, Lóránt Székvölgyi
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-12 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the death of motor neurons, the aetiology of which is essentially unknown. Here, we present an integrative epigenomic study in blood samples from seve
Externí odkaz:
https://doaj.org/article/f835840c5d2e4e40af2979ffd5e752d1
Autor:
Éva Juhász, Zsuzsanna Szabó, Andrew V. Schally, József Király, Petra Fodor, Gábor Kónya, Balázs Dezső, Erzsébet Szabó, Gábor Halmos, Csongor Kiss
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8831 (2024)
Hematological and oncological diseases are still among the leading causes of childhood mortality. Expression of growth hormone-releasing hormone (GHRH) and its receptors (GHRH-R) has been previously demonstrated in various human tumors, but very limi
Externí odkaz:
https://doaj.org/article/532b1062283c4e7eb83f31a45011fcaa
Autor:
József Király, Erzsébet Szabó, Petra Fodor, Anna Vass, Mahua Choudhury, Rudolf Gesztelyi, Csaba Szász, Tibor Flaskó, Nikoletta Dobos, Barbara Zsebik, Ákos József Steli, Gábor Halmos, Zsuzsanna Szabó
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1441 (2024)
Background: MicroRNAs (miRNAs) play a regulatory role in various human cancers. The roles of hsa-miR-15a-5p, hsa-miR-99b-5p, and hsa-miR-181a-5p have not been fully explored in the angiogenesis of renal cell carcinoma (RCC). Aims: The present study a
Externí odkaz:
https://doaj.org/article/83675b2679a046309d663e9a807f638a
Autor:
Ildikó Szabó, Beáta Biri-Kovács, Balázs Vári, Ivan Ranđelović, Diána Vári-Mező, Éva Juhász, Gábor Halmos, Szilvia Bősze, József Tóvári, Gábor Mező
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1095 (2024)
Malignant melanoma is one of the most aggressive and resistant tumor types, with high metastatic properties. Because of the lack of suitable chemotherapeutic agents for treatment, the 5-year survival rate of melanoma patients with regional and distan
Externí odkaz:
https://doaj.org/article/0682fb640e5e4aa18e97754831fcece1
Autor:
József Király, Erzsébet Szabó, Petra Fodor, Zsolt Fejes, Béla Nagy, Éva Juhász, Anna Vass, Mahua Choudhury, Gábor Kónya, Gábor Halmos, Zsuzsanna Szabó
Publikováno v:
Molecules, Vol 28, Iss 18, p 6725 (2023)
(1) Background: Shikonin, the main ingredient in Chinese herbal medicine, is described as a novel angiogenesis inhibitor, and its anticancer effects have already been studied. Shikonin and its derivatives induce apoptosis and suppress metastasis, whi
Externí odkaz:
https://doaj.org/article/c9caa15a1489492e9a3f62d8f4c20755
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12675 (2023)
Angiogenesis plays a crucial role in tumour progression and metastatic spread; therefore, the development of specific vectors targeting angiogenesis has attracted the attention of several researchers. Since angiogenesis-associated aminopeptidase N (A
Externí odkaz:
https://doaj.org/article/f08af9967edd4866ae8482b7401acc16
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5071 (2022)
The human gonadotropin releasing hormone (GnRH-I) and its sea lamprey analogue GnRH-III specifically bind to GnRH receptors on cancer cells and can be used as targeting moieties for targeted tumor therapy. Considering that the selective release of dr
Externí odkaz:
https://doaj.org/article/15d665ff4feb41e794d30225838ed6cc
Autor:
Sabine Schuster, Beáta Biri-Kovács, Bálint Szeder, Viktor Farkas, László Buday, Zsuzsanna Szabó, Gábor Halmos, Gábor Mező
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 756-771 (2018)
Gonadotropin releasing hormone-III (GnRH-III), a native isoform of the human GnRH isolated from sea lamprey, specifically binds to GnRH receptors on cancer cells enabling its application as targeting moieties for anticancer drugs. Recently, we report
Externí odkaz:
https://doaj.org/article/6ec30774b7a549dc8709643a02cb7791
Autor:
Zsuzsanna Szabó, Balázs Dezső, Klára Fodor, Krisztián Szegedi, Tibor Flaskó, Erzsébet Szabó, Gábor Oláh, Éva Sipos, Nikoletta Dobos, János Gardi, Andrew V. Schally, Gábor Halmos
Publikováno v:
Molecules, Vol 26, Iss 5, p 1253 (2021)
Bladder cancer (BC) is the tenth most frequently detected cancer in both sexes. Type-I luteinizing hormone-releasing hormone (LHRH) receptor (LHRH-R-I) is expressed not only in the pituitary, but also in several types of cancer disease. There are few
Externí odkaz:
https://doaj.org/article/f04a73b9071f40f2b7c6e2ae5b74033e
Autor:
Klára Fodor, Éva Sipos, Nikoletta Dobos, János Nagy, Zita Steiber, Gábor Méhes, Kata Dull, Lóránt Székvölgyi, Andrew V. Schally, Gábor Halmos
Publikováno v:
Life, Vol 10, Iss 12, p 310 (2020)
Uveal melanoma (UM) is the most common malignant tumor of the eye with extremely high metastatic potential. UM tumor cells can disseminate only hematogenously, thus, angiogenic signals have a particular role in the prognosis of the disease. Although
Externí odkaz:
https://doaj.org/article/2939d7e3c4f34e609d189b90f3ac5756