Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Gábor Benkovics"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 294-302 (2023)
The first continuous flow method was developed for the synthesis of 6-monoamino-6-monodeoxy-β-cyclodextrin starting from native β-cyclodextrin through three reaction steps, such as monotosylation, azidation and reduction. All reaction steps were st
Externí odkaz:
https://doaj.org/article/4a1cd5b856d34cc8a51c7d2f090b3d06
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14448 (2022)
Acid-base properties of cyclodextrins (CDs), persubstituted at C-6 by 3-mercaptopropionic acid, sualphadex (Suα-CD), subetadex (Suβ-CD) and sugammadex (Suγ-CD, the antidote of neuromuscular blocking steroids) were studied by 1H NMR-pH titrations.
Externí odkaz:
https://doaj.org/article/e6d78af637f347e2b532595165e60d49
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1888 (2022)
Chlorpromazine (CPZ) is an antipsychotic drug which can cause several adverse effects and drug poisoning. Recent studies demonstrated that CPZ forms highly stable complexes with certain cyclodextrins (CDs) such as sulfobutylether-β-CD (SBECD) and su
Externí odkaz:
https://doaj.org/article/9f1a21c30b3b4b8c8bd5475fca1ca1db
Autor:
Gábor Benkovics, Mihály Bálint, Éva Fenyvesi, Erzsébet Varga, Szabolcs Béni, Konstantina Yannakopoulou, Milo Malanga
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 710-720 (2019)
The regioselective difunctionalization of cyclodextrins (CDs) leading to derivatives amenable to further transformations is a daunting task due to challenging purification and unambiguous characterization of the obtained regioisomers with similar phy
Externí odkaz:
https://doaj.org/article/605b0f7ed7494c62a96cbef8af7cb1e8
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2829-2837 (2018)
The synthesis of batch-to-batch reproducible cyclodextrin (CD) derivatives often requires functionalization at specific positions of the CD skeleton. However, the regioselective preparation of this type of CD derivatives remains a challenge in synthe
Externí odkaz:
https://doaj.org/article/d6d47aaa26724eaaaa29ab246f8beb0e
Autor:
Gábor Benkovics, Damien Afonso, András Darcsi, Szabolcs Béni, Sabrina Conoci, Éva Fenyvesi, Lajos Szente, Milo Malanga, Salvatore Sortino
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 543-551 (2017)
Eosin B (EoB) and eosin Y (EoY), two xanthene dye derivatives with photosensitizing ability were prepared in high purity through an improved synthetic route. The dyes were grafted to a 6-monoamino-β-cyclodextrin scaffold under mild reaction conditio
Externí odkaz:
https://doaj.org/article/20ac40493df44a528fddf3c2a290d643
Autor:
Giovanna Cutrone, Xue Li, Juan M. Casas-Solvas, Mario Menendez-Miranda, Jingwen Qiu, Gábor Benkovics, Doru Constantin, Milo Malanga, Borja Moreira-Alvarez, José M. Costa-Fernandez, Luis García-Fuentes, Ruxandra Gref, Antonio Vargas-Berenguel
Publikováno v:
Nanomaterials, Vol 9, Iss 8, p 1103 (2019)
Nanosized metal-organic frameworks (nanoMOFs) MIL-100(Fe) are highly porous and biodegradable materials that have emerged as promising drug nanocarriers. A challenging issue concerns their surface functionalization in order to evade the immune system
Externí odkaz:
https://doaj.org/article/de6b2e47a8d04434b12c97a40bc0d800
Autor:
Giovanna Cutrone, Milo Malanga, Antonio Vargas-Berenguel, Juan M. Casas-Solvas, Gábor Benkovics, Szabolcs Béni
Publikováno v:
Nature Protocols. 16:965-987
Per(6-O-tert-butyldimethylsilyl)-α-, β- and γ-cyclodextrin derivatives are well-known as synthetic intermediates that enable the selective mono-, partial, or perfunctionalization of the secondary face of the macrocycles. Although silylation of the
Autor:
Dóra Ujj, Eszter Kalydi, Milo Malanga, Erzsébet Varga, Tamás Sohajda, Szabolcs Béni, Gábor Benkovics
Publikováno v:
Journal of Chromatography A. 1683:463506
The present contribution describes the application of three single-isomeric cyclodextrin derivatives for the first time - Sugammadex, Subetadex and Sualphadex as chiral selectors. Their recognition ability was investigated by means of chiral capillar
Autor:
Sulaiman Krait, Tamás Sohajda, Bezhan Chankvetadze, Paola Peluso, Gerhard K. E. Scriba, Antonio Salgado, Christian Neusüß, Gábor Benkovics, Lukas Naumann, Milo Malanga
Publikováno v:
Carbohydrate polymers 273 (2021): 118486. doi:10.1016/j.carbpol.2021.118486
info:cnr-pdr/source/autori:S. Krait, A. Salgado, P. Peluso, M. Malanga, T. Sohajda, G. Benkovics, L. Naumanne, C. Neusüß, B. Chankvetadze, G. K. E. Scriba/titolo:Complexation of daclatasvir by single isomer methylated beta-cyclodextrins studied by capillary electrophoresis, NMR spectroscopy and mass spectrometry/doi:10.1016%2Fj.carbpol.2021.118486/rivista:Carbohydrate polymers/anno:2021/pagina_da:118486/pagina_a:/intervallo_pagine:118486/volume:273
info:cnr-pdr/source/autori:S. Krait, A. Salgado, P. Peluso, M. Malanga, T. Sohajda, G. Benkovics, L. Naumanne, C. Neusüß, B. Chankvetadze, G. K. E. Scriba/titolo:Complexation of daclatasvir by single isomer methylated beta-cyclodextrins studied by capillary electrophoresis, NMR spectroscopy and mass spectrometry/doi:10.1016%2Fj.carbpol.2021.118486/rivista:Carbohydrate polymers/anno:2021/pagina_da:118486/pagina_a:/intervallo_pagine:118486/volume:273
In capillary electrophoresis an enantioseparation of daclatasvir (DCV) was observed in case of heptakis(2,6-di-O-methyl)-beta-CD, heptakis(2-O-methyl)-beta-CD and beta-CD, while two peaks with a plateau were noted for heptakis(2,3,6-tri-O-methyl)-bet