Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Gábor B. Brenner"'
Autor:
Csenger Kovácsházi, Szabolcs Hambalkó, Nabil V. Sayour, Tamás G. Gergely, Gábor B. Brenner, Csilla Pelyhe, Dóra Kapui, Bennet Y. Weber, Alexander L. Hültenschmidt, Éva Pállinger, Edit I. Buzás, Ádám Zolcsák, Bálint Kiss, Tamás Bozó, Csilla Csányi, Nikolett Kósa, Miklós Kellermayer, Róbert Farkas, Gellért B. Karvaly, Kieran Wynne, David Matallanas, Péter Ferdinandy, Zoltán Giricz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Hypercholesterolemia (HC) induces, propagates and exacerbates cardiovascular diseases via various mechanisms that are yet not properly understood. Extracellular vesicles (EVs) are involved in the pathomechanism of these diseases. To understa
Externí odkaz:
https://doaj.org/article/af891ef4f6eb4aa6a97926bd769c49dc
Autor:
Tamás G. Gergely, Gábor B. Brenner, Regina N. Nagy, Nabil V. Sayour, András Makkos, Csenger Kovácsházi, Huimin Tian, Rainer Schulz, Zoltán Giricz, Anikó Görbe, Péter Ferdinandy
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1585 (2023)
Lipid-lowering drugs have been shown to have cardioprotective effects but may have hidden cardiotoxic properties. Therefore, here we aimed to investigate if chronic treatment with the novel lipid-lowering drug bempedoic acid (BA) exerts hidden cardio
Externí odkaz:
https://doaj.org/article/17e87be51e874adc966ccfd71a3a1ed0
Autor:
Imre Vörös, Éva Sághy, Krisztina Pohóczky, András Makkos, Zsófia Onódi, Gábor B. Brenner, Tamás Baranyai, Bence Ágg, Barnabás Váradi, Ágnes Kemény, Przemyslaw Leszek, Anikó Görbe, Zoltán V. Varga, Zoltán Giricz, Rainer Schulz, Zsuzsanna Helyes, Péter Ferdinandy
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Little is known about the role of the neuropeptide somatostatin (SST) in myocardial ischemia/reperfusion injury and cardioprotection. Here, we investigated the direct cardiocytoprotective effect of SST on ischemia/reperfusion injury in cardiomyocyte
Externí odkaz:
https://doaj.org/article/dcbc88f896f543ad8ae2da1ca762c860
Autor:
Bennet Y. Weber, Gábor B. Brenner, Bernadett Kiss, Tamás G. Gergely, Nabil V. Sayour, Huimin Tian, András Makkos, Anikó Görbe, Péter Ferdinandy, Zoltán Giricz
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1055 (2022)
Clinical observations are highly inconsistent with the use of the antidiabetic rosiglitazone regarding its associated increased risk of myocardial infarction. This may be due to its hidden cardiotoxic properties that have only become evident during p
Externí odkaz:
https://doaj.org/article/be592a902bfc4549be3705bd481e22c9
Autor:
Kitti Szoták-Ajtay, Dániel Szõke, Gábor Kovács, Judit Andréka, Gábor B. Brenner, Zoltán Giricz, Josef Penninger, Mark L. Kahn, Zoltán Jakus
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Embryonic lungs must be inflated immediately after birth to establish respiration. In addition to pulmonary surfactant, recently, we have revealed lymphatic function as a previously unknown regulator of prenatal lung compliance that prepares the embr
Externí odkaz:
https://doaj.org/article/7383518730544accb2f7c18fed886b0d
Autor:
Peter Pečan, Szabolcs Hambalkó, Van Thai Ha, Csilla T. Nagy, Csilla Pelyhe, Duško Lainšček, Bence Kenyeres, Gábor B. Brenner, Anikó Görbe, Ágnes Kittel, Monika Barteková, Péter Ferdinandy, Mateja Manček-Keber, Zoltán Giricz
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7687 (2020)
Cardioprotection against ischemia/reperfusion injury is still an unmet clinical need. The transient activation of Toll-like receptors (TLRs) has been implicated in cardioprotection, which may be achieved by treatment with blood-derived extracellular
Externí odkaz:
https://doaj.org/article/b260a6f524c04976ab8f320b6f9f2062
Autor:
Gábor B. Brenner, András Makkos, Csilla Terézia Nagy, Zsófia Onódi, Nabil V. Sayour, Tamás G. Gergely, Bernadett Kiss, Anikó Görbe, Éva Sághy, Zoltán S. Zádori, Bernadette Lázár, Tamás Baranyai, Richárd S. Varga, Zoltán Husti, András Varró, László Tóthfalusi, Rainer Schulz, István Baczkó, Zoltán Giricz, Péter Ferdinandy
Publikováno v:
Cells, Vol 9, Iss 3, p 551 (2020)
Cardiac adverse effects are among the leading causes of the discontinuation of clinical trials and the withdrawal of drugs from the market. The novel concept of ‘hidden cardiotoxicity’ is defined as cardiotoxicity of a drug that manifests in the
Externí odkaz:
https://doaj.org/article/e64b79f188254c80abf4399ea382fcad
Autor:
Zsófia Onódi, Csilla Pelyhe, Csilla Terézia Nagy, Gábor B. Brenner, Laura Almási, Ágnes Kittel, Mateja Manček-Keber, Péter Ferdinandy, Edit I. Buzás, Zoltán Giricz
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Background: Extracellular vesicles (EVs) (isolated from blood plasma) are currently being extensively researched, both as biomarkers and for their therapeutic possibilities. One challenging aspect to this research is the efficient isolation of high-p
Externí odkaz:
https://doaj.org/article/1af025ed0b564df6a1f9569fd70a7f8d
Autor:
Bernadette Lázár, Gábor B. Brenner, András Makkos, Mihály Balogh, Szilvia B. László, Mahmoud Al-Khrasani, Barbara Hutka, Emese Bató, Eszter Ostorházi, János Juhász, Ágnes Kemény, Terézia László, László Tiszlavicz, Zoltán Bihari, Zoltán Giricz, Dóra Szabó, Zsuzsanna Helyes, Péter Ferdinandy, Klára Gyires, Zoltán S. Zádori
Publikováno v:
Cells, Vol 8, Iss 3, p 251 (2019)
Intestinal dysbiosis is linked to numerous gastrointestinal disorders, including inflammatory bowel diseases. It is a question of debate if coxibs, selective inhibitors of cyclooxygenase (COX)-2, cause dysbiosis. Therefore, in the present study, we a
Externí odkaz:
https://doaj.org/article/447f416e8ec148d5adc5ca8abc2b227f
Autor:
Nabil V Sayour, Gábor B Brenner, András Makkos, Bernadett Kiss, Csenger Kovácsházi, Tamás G Gergely, Sverre Groever Aukrust, Huimin Tian, Viktória Zenkl, Kamilla Gömöri, Tamara Szabados, Péter Bencsik, Andre Heinen, Rainer Schulz, Gary F Baxter, Coert J Zuurbier, Zoltán Vokó, Péter Ferdinandy, Zoltán Giricz
Publikováno v:
Caridovascular Research
Aims Remote ischaemic preconditioning (RIPC) is a robust cardioprotective intervention in preclinical studies. To establish a working and efficacious RIPC protocol in our laboratories, we performed randomized, blinded in vivo studies in three study c