Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Gábor, Mező"'
Autor:
László Imre, Péter Nánási, Ibtissem Benhamza, Kata Nóra Enyedi, Gábor Mocsár, Rosevalentine Bosire, Éva Hegedüs, Erfaneh Firouzi Niaki, Ágota Csóti, Zsuzsanna Darula, Éva Csősz, Szilárd Póliska, Beáta Scholtz, Gábor Mező, Zsolt Bacsó, H. T. Marc Timmers, Masayuki Kusakabe, Margit Balázs, György Vámosi, Juan Ausio, Peter Cheung, Katalin Tóth, David Tremethick, Masahiko Harata, Gábor Szabó
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract H2A.Z-nucleosomes are present in both euchromatin and heterochromatin and it has proven difficult to interpret their disparate roles in the context of their stability features. Using an in situ assay of nucleosome stability and DT40 cells ex
Externí odkaz:
https://doaj.org/article/9f75e506bb0545b4a0d43f62434ffc30
Publikováno v:
ACS Omega, Vol 9, Iss 6, Pp 6894-6900 (2024)
Externí odkaz:
https://doaj.org/article/5d9ff418dc294e90a5ae304cf9a25ecf
Autor:
Balázs Vári, Levente Dókus, Adina Borbély, Anikó Gaál, Diána Vári-Mező, Ivan Ranđelović, Anna Sólyom-Tisza, Zoltán Varga, Norbert Szoboszlai, Gábor Mező, József Tóvári
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractChemotherapy is still a leading therapeutic approach in various tumor types that is often accompanied by a poor prognosis because of metastases. PEGylated liposomes with CREKA targeting moiety are well-known therapeutic agents, especially in
Externí odkaz:
https://doaj.org/article/20072f91186a426695d8bc4c72c657cf
Autor:
Gergely Farkasinszky, Judit Szabó Péliné, Péter Károlyi, Szilvia Rácz, Noémi Dénes, Tamás Papp, József Király, Zsuzsanna Szabo, István Kertész, Gábor Mező, Gabor Halmos, Zita Képes, György Trencsényi
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 542 (2024)
Background: To better understand ischaemia-related molecular alterations, temporal changes in angiogenic Aminopeptidase N (APN/CD13) expression and glucose metabolism were assessed with PET using a rat model of peripheral arterial disease (PAD). Meth
Externí odkaz:
https://doaj.org/article/2922067021fc41558236fb02f2d7df70
Autor:
Marco Zambra, Ivan Ranđelović, Francesco Talarico, Adina Borbély, Laura Svajda, József Tóvári, Gábor Mező, Lizeth Bodero, Sveva Colombo, Federico Arrigoni, Elettra Fasola, Silvia Gazzola, Umberto Piarulli
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Antibody-Drug Conjugates (ADCs) and Small Molecule-Drug Conjugates (SMDCs) represent successful examples of targeted drug-delivery technologies for overcoming unwanted side effects of conventional chemotherapy in cancer treatment. In both strategies,
Externí odkaz:
https://doaj.org/article/8398d4cb126548328281d797762b4133
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 907 (2022)
Cell-penetrating peptides (CPP) are promising tools for the transport of a broad range of compounds into cells. Since the discovery of the first members of this peptide family, many other peptides have been identified; nowadays, dozens of these pepti
Externí odkaz:
https://doaj.org/article/0ffb713256c34f2ba14b46dce6f2d361
Autor:
Eszter Lajkó, Sarah Spring, Rózsa Hegedüs, Beáta Biri-Kovács, Sven Ingebrandt, Gábor Mező, László Kőhidai
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2495-2509 (2018)
Background: Peptide hormone-based targeted tumor therapy is an approved strategy to selectively block the tumor growth and spreading. The gonadotropin-releasing hormone receptors (GnRH-R) overexpressed on different tumors (e.g., melanoma) could be ut
Externí odkaz:
https://doaj.org/article/8fbdc195542345c69ea27f0ff4c714bb
Autor:
Livia Polgár, Eszter Lajkó, Pál Soós, Orsolya Láng, Marilena Manea, Béla Merkely, Gábor Mező, László Kőhidai
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1583-1594 (2018)
Background: Cardiomyopathy induced by the chemotherapeutic agents doxorubicin and daunorubicin is a major limiting factor for their application in cancer therapy. Chemotactic drug targeting potentially increases the tumor selectivity of drugs and dec
Externí odkaz:
https://doaj.org/article/52e2ab83540244008ec908e8c7eb8be5
Autor:
Andrea Angelo Pierluigi Tripodi, Szilárd Tóth, Kata Nóra Enyedi, Gitta Schlosser, Gergely Szakács, Gábor Mező
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 911-918 (2018)
Cyclic NGR peptides as homing devices are good candidates for the development of drug conjugates for targeted tumor therapy. In our previous study we reported that the Dau=Aoa-GFLGK(c[KNGRE]-GG-)-NH2 conjugate has a significant antitumor activity aga
Externí odkaz:
https://doaj.org/article/0849990b48c64223a0c380c04e568ae1
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 930-954 (2018)
Cancer is the second leading cause of death affecting nearly one in two people, and the appearance of new cases is projected to rise by >70% by 2030. To effectively combat the menace of cancer, a variety of strategies have been exploited. Among them,
Externí odkaz:
https://doaj.org/article/ab5f0fd6b9ce415ba50548b2e8221789