Selection of microsatellite markers for bladder cancer diagnosis without the need for corresponding blood.

Autor: Angela A G van Tilborg, Lucie C Kompier, Irene Lurkin, Ricardo Poort, Samira El Bouazzaoui, Kirstin van der Keur, Tahlita Zuiverloon, Lars Dyrskjot, Torben F Orntoft, Monique J Roobol, Ellen C Zwarthoff

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e43345 (2012)

Microsatellite markers are used for loss-of-heterozygosity, allelic imbalance and clonality analyses in cancers. Usually, tumor DNA is compared to corresponding normal DNA. However, normal DNA is not always available and can display aberrant allele r

Externí odkaz: https://doaj.org/article/0c4ca61dc0bf4194a0f747c3dda52fcb

Age at diagnosis as an indicator of eligibility for BRCA1 DNA testing in familial breast cancer

Autor: R. S. Cornells, H. F. A. Vasen, H. Meijers-Heijboer, D. Ford, M. van Vliet, A. A. G. van Tilborg, F. J. Cleton, J. G. M. Klijn, F. H. Menko, P. Meera Khan, C. J. Cornelisse, P. Devilee

Publikováno v: Human genetics, 95(5), 539-544. Springer Verlag

We searched for criteria that could indicate breast cancer families with a high prior probability of being caused by the breast/ovarian cancer susceptibility locus BRCA1 on chromosome 17. To this end, we performed a linkage study with 59 consecutivel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9465a579d9a88d8765c794dbafd39841
https://doi.org/10.1007/bf00223866

In-depth investigation of the molecular pathogenesis of bladder cancer in a unique 26-year old patient with extensive multifocal disease: a case report

Autor: Cheno Abas, Ellen C. Zwarthoff, Angela G van Tilborg, Tahlita C.M. Zuiverloon, Martijn B. Busstra, Marcel Vermeij, Stephen S. Tjin, Kirstin A. van der Keur

Publikováno v: BMC Urology, 10. BioMed Central Ltd.
BMC Urology, Vol 10, Iss 1, p 5 (2010)
BMC Urology

Background The molecular characteristics and the clinical disease course of bladder cancer (BC) in young patients remain largely unresolved. All patients are monitored according to an intensive surveillance protocol and we aim to gain more insight in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ddc8f82fbe5cdf7031097a2c1f30b15
https://doi.org/10.1186/1471-2490-10-5

The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids

Autor: P. C. de Witt Hamer, C. J. F. Van Noorden, Peter Sminia, Paul P. Eijk, A A G Van Tilborg, Dirk Troost, Sieger Leenstra, Bauke Ylstra

Publikováno v: Oncogene, 27(14), 2091-2096. Nature Publishing Group
de Witt Hamer, P C, van Tilborg, A A, Eijk, P P, Sminia, P, Troost, D, van Noorden, C J, Ylstra, B & Leenstra, S 2008, ' The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids ', Oncogene, vol. 27, no. 14, pp. 2091-2096 . https://doi.org/10.1038/sj.onc.1210850

Screening of therapeutics relies on representative cancer models. The representation of human glioblastoma by in vitro cell culture models is questionable. We obtained genomic profiles by array comparative genomic hybridization of both short- and lon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c854747e068a7761809db065b90ae27
https://pure.eur.nl/en/publications/68563aa2-8a57-4484-9c4a-fde4316b3cad

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