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Autor:
Funda Meric-Bernstam, Razelle Kurzrock, Gordon B. Mills, Geert Maertens, Erwin Sablon, Benoit Devogelaere, Sapna Patel, Bryan K. Kee, Michael J. Overman, Scott Kopetz, Rajyalakshmi Luthra, Vivek Subbiah, Ralph G. Zinner, Veronica R. Holley, Daniel D. Karp, Jennifer J. Wheler, Sarina A. Piha-Paul, Aung Naing, Apostolia M. Tsimberidou, Goran Cabrilo, Giovanni Nitti, Nishma M. Ramzanali, David Hong, Siqing Fu, Gerald S. Falchook, Bart Claes, Helen J. Huang, Filip Janku
Cell-free (cf) DNA from plasma offers an easily obtainable material for BRAF mutation analysis for diagnostics and response monitoring. In this study, plasma-derived cfDNA samples from patients with progressing advanced cancers or malignant histiocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ef94582c1c6f3d6a2f4d621403ca07
https://doi.org/10.1158/1535-7163.c.6537582.v1
https://doi.org/10.1158/1535-7163.c.6537582.v1
Autor:
Jennifer J. Wheler, Razelle Kurzrock, Funda Meric-Bernstam, Roman Yelensky, Philip Stephens, Bettzy Stephen, David Hong, Apostolia M. Tsimberidou, Siqing Fu, Aung Naing, Ralph G. Zinner, Vicente Valero, Filip Janku, J. Jack Lee, Stacy Moulder, Prasanth Ganesan
Supplementary Table S1. Description of targeted therapies used in various phase I trials involved in various phase I trials (n=106)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc6162a6428c2f8bc41a5a06201ab28
https://doi.org/10.1158/1535-7163.22501554
https://doi.org/10.1158/1535-7163.22501554
Autor:
Jennifer J. Wheler, Razelle Kurzrock, Funda Meric-Bernstam, Roman Yelensky, Philip Stephens, Bettzy Stephen, David Hong, Apostolia M. Tsimberidou, Siqing Fu, Aung Naing, Ralph G. Zinner, Vicente Valero, Filip Janku, J. Jack Lee, Stacy Moulder, Prasanth Ganesan
Patients with metastatic triple-negative breast cancer (TNBC) have poor treatment outcomes. We reviewed the electronic records of consecutive patients with metastatic TNBC treated in phase I clinic at MD Anderson Cancer Center (Houston, TX) between A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c87d2a12aad58bad9d74cc39679e028
https://doi.org/10.1158/1535-7163.c.6536826.v1
https://doi.org/10.1158/1535-7163.c.6536826.v1
Autor:
Funda Meric-Bernstam, Razelle Kurzrock, Gordon B. Mills, Geert Maertens, Erwin Sablon, Benoit Devogelaere, Sapna Patel, Bryan K. Kee, Michael J. Overman, Scott Kopetz, Rajyalakshmi Luthra, Vivek Subbiah, Ralph G. Zinner, Veronica R. Holley, Daniel D. Karp, Jennifer J. Wheler, Sarina A. Piha-Paul, Aung Naing, Apostolia M. Tsimberidou, Goran Cabrilo, Giovanni Nitti, Nishma M. Ramzanali, David Hong, Siqing Fu, Gerald S. Falchook, Bart Claes, Helen J. Huang, Filip Janku
Supplementary Table 1. Emergence of BRAF mutations in cfDNA; Supplementary Table 2. Patients with BRAF V600K mutations in FFPE tumor and plasma cfDNA samples; Supplementary Table 3. Experimental therapies in 34 patients with longitudinal collection o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a225a4b89a691edeccc2bf76884a81a5
https://doi.org/10.1158/1535-7163.22503987
https://doi.org/10.1158/1535-7163.22503987
Autor:
John H. Miller, Scott M. Lippman, Waun K. Hong, Li Mao, Gordon B. Mills, Claudio Pisano, Hai T. Tran, Reuben Lotan, Juri G. Gelovani, Andrei Y. Volgin, Paul Damien, Elmira Popova, Brittany L. Barrett, Ralph G. Zinner
Supplementary Fig. S3 from Algorithmic guided screening of drug combinations of arbitrary size for activity against cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878d72da25164463179258048356f2ff
https://doi.org/10.1158/1535-7163.22485888
https://doi.org/10.1158/1535-7163.22485888
Autor:
John H. Miller, Scott M. Lippman, Waun K. Hong, Li Mao, Gordon B. Mills, Claudio Pisano, Hai T. Tran, Reuben Lotan, Juri G. Gelovani, Andrei Y. Volgin, Paul Damien, Elmira Popova, Brittany L. Barrett, Ralph G. Zinner
Supplementary Methods from Algorithmic guided screening of drug combinations of arbitrary size for activity against cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb4eff4dcbc1100b980dcea51742983
https://doi.org/10.1158/1535-7163.22485885.v1
https://doi.org/10.1158/1535-7163.22485885.v1
Autor:
John H. Miller, Scott M. Lippman, Waun K. Hong, Li Mao, Gordon B. Mills, Claudio Pisano, Hai T. Tran, Reuben Lotan, Juri G. Gelovani, Andrei Y. Volgin, Paul Damien, Elmira Popova, Brittany L. Barrett, Ralph G. Zinner
Supplementary Table S1 from Algorithmic guided screening of drug combinations of arbitrary size for activity against cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5535e10be42396a30779658fef789925
https://doi.org/10.1158/1535-7163.22485882.v1
https://doi.org/10.1158/1535-7163.22485882.v1
Autor:
David S. Hong, Funda Meric-Berstam, Lee M. Ellis, Razelle Kurzrock, Ralph G. Zinner, Jennifer Wheler, Vivek Subbiah, Sarina Piha-Paul, Aung Naing, Filip Janku, Siqing Fu, Gerald Falchook, Apostolia M. Tsimberidou, Debora De Melo Gagliato, Denis Leonardo F. Jardim, Kenneth Hess, Chad Tang
Supplementary Tables. Supplemental Table 1: Frequency of specific MET, NRAS, and KRAS mutations Supplemental Table 2. Distribution of patients with BRAF mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afac80ebfe3bfc3c8b969defdf2d125
https://doi.org/10.1158/1078-0432.22455473
https://doi.org/10.1158/1078-0432.22455473
Autor:
John H. Miller, Scott M. Lippman, Waun K. Hong, Li Mao, Gordon B. Mills, Claudio Pisano, Hai T. Tran, Reuben Lotan, Juri G. Gelovani, Andrei Y. Volgin, Paul Damien, Elmira Popova, Brittany L. Barrett, Ralph G. Zinner
The standard treatment for most advanced cancers is multidrug therapy. Unfortunately, combinations in the clinic often do not perform as predicted. Therefore, to complement identifying rational drug combinations based on biological assumptions, we hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5bbaca93ba6f4d0a495e8d1b19c93f9
https://doi.org/10.1158/1535-7163.c.6532122.v1
https://doi.org/10.1158/1535-7163.c.6532122.v1