Zobrazeno 1 - 10
of 669
pro vyhledávání: '"G, Zech"'
Autor:
Christopher Fotsch, Debaleena Basu, Ryan Case, Qing Chen, Pratibha C. Koneru, Mei-Chu Lo, Rachel Ngo, Pooja Sharma, Amit Vaish, Xiang Yi, Stephan G. Zech, Peter Hodder
Publikováno v:
SLAS Discovery, Vol 29, Iss 4, Pp 100159- (2024)
To confirm target engagement of hits from our high-throughput screening efforts, we ran biophysical assays on several hundreds of hits from 15 different high-throughput screening campaigns. Analyzing the biophysical assay results from these screening
Externí odkaz:
https://doaj.org/article/2deb87592cfb4d24ab3ef0bdbdb9d00b
Publikováno v:
Accounts of Chemical Research. 55:2892-2903
ConspectusNearly a century after its first description, configurationally stable axial chirality remains a rare feature in marketed drugs. In the development of the KRAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa33be4d8cb13730846b9101f1da93e
https://doi.org/10.1021/acs.accounts.2c00479
https://doi.org/10.1021/acs.accounts.2c00479
Publikováno v:
Journal of Experimental Psychology: General.
Researchers have suggested that overconsumption of food, alcohol, and drugs could be explained by chronically elevated approach tendencies to rewarding but unhealthy stimuli. Here, we use the example of food to show that dysregulated rather than chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec046f1b0ece6a32d23bb80b4cad0c2
https://doi.org/10.1037/xge0001386
https://doi.org/10.1037/xge0001386
Autor:
Victor M. Rivera, Xiaotian Zhu, Kwok-kin Wong, Shengwu Liu, Robert J. Griffin, Johara Chouitar, Michael Fitzgerald, William C. Shakespeare, David Dalgarno, Tim Clackson, Narayana I. Narasimhan, Biplab Das, Stephan G. Zech, Matthew T. Greenfield, Feng Li, Yongbo Hu, Wei-Sheng Huang, Sen Zhang, Yaoyu Ning, Sara Nadworny, Scott D. Wardwell, Shuai Li, Alexandra E. Gould, Theresa E. Baker, Sylvie Vincent, Francois Gonzalvez
Most EGFR exon 20 insertion (EGFRex20ins) driver mutations in non–small cell lung cancer (NSCLC) are insensitive to approved EGFR tyrosine kinase inhibitors (TKI). To address the limitations of existing therapies targeting EGFR-mutated NSCLC, moboc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1233d4a09c246c7e577a052bb61a6464
https://doi.org/10.1158/2159-8290.c.6549370.v1
https://doi.org/10.1158/2159-8290.c.6549370.v1
Autor:
Victor M. Rivera, Xiaotian Zhu, Kwok-kin Wong, Shengwu Liu, Robert J. Griffin, Johara Chouitar, Michael Fitzgerald, William C. Shakespeare, David Dalgarno, Tim Clackson, Narayana I. Narasimhan, Biplab Das, Stephan G. Zech, Matthew T. Greenfield, Feng Li, Yongbo Hu, Wei-Sheng Huang, Sen Zhang, Yaoyu Ning, Sara Nadworny, Scott D. Wardwell, Shuai Li, Alexandra E. Gould, Theresa E. Baker, Sylvie Vincent, Francois Gonzalvez
Supplementary Tables (S1-6) and Figures (S1-6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b1686b17282cc4afaa22ed044b1306
https://doi.org/10.1158/2159-8290.22540399
https://doi.org/10.1158/2159-8290.22540399
Autor:
Anne-Marie Brouwer, Jasper J. van Beers, Priya Sabu, Ivo V. Stuldreher, Hilmar G. Zech, Daisuke Kaneko
Publikováno v:
Foods, Vol 10, Iss 7, p 1440 (2021)
Implicit (‘unconscious’) approach–avoidance tendencies towards stimuli can be measured using the Approach Avoidance Task (AAT). We recently expanded a toolbox for analyzing the raw data of a novel, mobile version of the AAT (mAAT), that asks pa
Externí odkaz:
https://doaj.org/article/2ab6f2c7a37849d090889572734d2ff2
Autor:
Hilmar G. Zech, Markus Reichert, Ulrich W. Ebner-Priemer, Heike Tost, Michael A. Rapp, Andreas Heinz, Raymond J. Dolan, Michael N. Smolka, Lorenz Deserno
Publikováno v:
Neuropsychobiology
Neuropsychobiology, 81 (5), 438–450
Neuropsychobiology, 81 (5), 438–450
Introduction: Over the last decades, our understanding of the cognitive, motivational, and neural processes involved in addictive behavior has increased enormously. A plethora of laboratory-based and cross-sectional studies has linked cognitive-behav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dc21df5e7f914f8b2847a3c0d1f49a
https://doi.org/10.1159/000523697
https://doi.org/10.1159/000523697
Autor:
Matthew J. Belanger, Hao Chen, Angela Hentschel, Maria Garbusow, Claudia Ebrahimi, Felix G. Knorr, Hilmar G. Zech, Maximilian Pilhatsch, Andreas Heinz, Michael N. Smolka
Publikováno v:
Neuropsychobiology. 81:370-386
Introduction: The emergence of Pavlovian-to-instrumental transfer (PIT) research in the human neurobehavioral domain has been met with increased interest over the past two decades. A variety of PIT tasks were developed during this time; while success
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae78bb2b4a23d285d380a238a9ca460
https://doi.org/10.1159/000526774
https://doi.org/10.1159/000526774
Autor:
S. GJESDAL, G. PRESSER, T. KAMAE, P. STEFFEN, J. STEINBERGER, F. VANNUCCI, H. WAHL, F. EISELE, H. FILTHUTH, V. LÜTH, G. ZECH, K. KLEINKNECHT
Publikováno v:
Memorial Volume for Jack Steinberger ISBN: 9789811264429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4a9e56374fdd580ef8067e8f8e9c355
https://doi.org/10.1142/9789811264436_0015
https://doi.org/10.1142/9789811264436_0015
Autor:
C. GEWENIGER, S. GJESDAL, G. PRESSER, P. STEFFEN, J. STEINBERGER, F. VANNUCCI, H. WAHL, F. EISELE, H. FILTHUTH, K. KLEINKNECHT, V. LÜTH, G. ZECH
Publikováno v:
Memorial Volume for Jack Steinberger ISBN: 9789811264429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e908056bda200265bc5819f57e1f5e1d
https://doi.org/10.1142/9789811264436_0014
https://doi.org/10.1142/9789811264436_0014