Zobrazeno 1 - 10
of 4 806
pro vyhledávání: '"G, WELLS"'
Autor:
Adi Har-Zahav, Ana Tobar, Sophia Fried, Rachel Sivan, Benjamin J. Wilkins, Pierre Russo, Raanan Shamir, Rebecca G. Wells, Michael Gurevich, Orith Waisbourd-Zinman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Cholangiopathies are poorly understood disorders with no effective therapy. The extrahepatic biliary tree phenotype is less studied compared to the intrahepatic biliary injury in both human disease and Mdr2−/− mice, the established chole
Externí odkaz:
https://doaj.org/article/34c1fd020f514c50a4174d000e53510f
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-13 (2024)
Abstract Huntington's disease (HD) is a devastating neurodegenerative disorder caused by aggregation of the mutant huntingtin (mHTT) protein, resulting from a CAG repeat expansion in the huntingtin gene HTT. HD is characterized by a variety of debili
Externí odkaz:
https://doaj.org/article/7d25014419f64bbcbdb53a21c25fd2dc
Autor:
Kapish Gupta, Jessica Llewellyn, Emilia Roberts, Chengyang Liu, Ali Naji, Richard K. Assoian, Rebecca G. Wells
Publikováno v:
JHEP Reports, Vol 7, Iss 1, Pp 101215- (2025)
Background & Aims: EGF-containing fibulin extracellular matrix protein 1 (EFEMP1, also called fibulin-3) is an extracellular matrix protein linked in a genome-wide association study to biliary atresia, a fibrotic disease of the neonatal extrahepatic
Externí odkaz:
https://doaj.org/article/a61f630ea9b74a539accc9846e8509a0
Publikováno v:
JHEP Reports, Vol 7, Iss 1, Pp 101218- (2025)
Background & Aims: Biliary atresia is a fibrosing cholangiopathy affecting neonates that is thought to result from a prenatal environmental insult to the bile duct. Biliatresone, a plant toxin with an α-methylene ketone group, was previously implica
Externí odkaz:
https://doaj.org/article/24e4b22810cf4291a9cabfd2897c23c3
Autor:
Astrid Raynard, Anam Abbas, Steven Armstrong, Gary G. Wells, Glen McHale, Khellil Sefiane, Daniel Orejon
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Controlling the dynamics of droplet evaporation is critical to numerous fundamental and industrial applications. The three main modes of evaporation so far reported on smooth surfaces are the constant contact radius (CCR), constant contact a
Externí odkaz:
https://doaj.org/article/fd5c7b46ed6a402b957e3e864087af36
Autor:
Tyler J. Pease, BS, G. Wells Ducas, BS, Michael L. Raffetto, MD, Andrew C. Bernard, MD, Jalen A. Martin, BA, Paul E. Matuszewski, MD
Publikováno v:
OTA International, Vol 7, Iss 2 (2024)
Abstract. Purpose:. To identify factors associated with delays in administration and pharmacy and nursing preparation of antibiotics for patients with open fractures. Design:. Retrospective review. Setting:. Level I trauma center. Patients:. Nine hun
Externí odkaz:
https://doaj.org/article/58937920e75e4a7f9edb3e71bbb9ce6a
Autor:
Glen McHale, Andrew Alderson, Steven Armstrong, Shruti Mandhani, Mahya Meyari, Gary G. Wells, Emma Carter, Rodrigo Ledesma‐Aguilar, Ciro Semprebon, Kenneth E. Evans
Publikováno v:
Small Structures, Vol 5, Iss 4, Pp n/a-n/a (2024)
Superhydrophobic materials are often inspired by nature, whereas metamaterials are engineered to have properties not usually occurring naturally. In both, the key to their unique properties is structure. Here, it is shown that a negative Poisson's ra
Externí odkaz:
https://doaj.org/article/53e06d1c9ce84742aa3d781b3f032ef8
Autor:
Danielle M. Drake, Kian Afsharian, Benjamin Or, Aaron M. Shapiro, Michelle L. Lai, Lutfiya Miller, Peter G. Wells
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103070- (2024)
Although widely known as a tumor suppressor, the breast cancer 1 susceptibility protein (BRCA1) is also important in development, where it regulates fetal DNA repair pathways that protect against DNA damage caused by physiological and drug-enhanced l
Externí odkaz:
https://doaj.org/article/41425faa30ac481d8fe65cebd14ab96d
Autor:
Kapish Gupta, Jimmy P Xu, Tamir Diamond, Iris E M de Jong, Andrew Glass, Jessica Llewellyn, Neil D Theise, Orith Waisbourd-Zinman, Jeffrey D Winkler, Edward M Behrens, Clementina Mesaros, Rebecca G Wells
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301824 (2024)
Biliary atresia is a neonatal disease characterized by damage, inflammation, and fibrosis of the liver and bile ducts and by abnormal bile metabolism. It likely results from a prenatal environmental exposure that spares the mother and affects the fet
Externí odkaz:
https://doaj.org/article/74507efcbeca4a1daf62e83fff6e33fb
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 6, Pp 251-261 (2023)
Abstract Fat accumulation during liver steatosis precedes inflammation and fibrosis in fatty liver diseases, and is associated with disease progression. Despite a large body of evidence that liver mechanics play a major role in liver disease progress
Externí odkaz:
https://doaj.org/article/9ab82083e59041d1b6845d3a692f3442