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c-MYC and h-TERT co-expression in colon adenocarcinoma: a tissue microarray digitized image analysis

Autor: G, Georgakopoulos, E, Tsiambas, P, Korkolopoulos, P, Korkolopoulou, N, Kavantzas, A, Karameris, V, Ragkos, D N, Rigopoulos, G, Vilaras, E, Patsouris, A E, Athanasiou, D, Tatsiou

Publikováno v: Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 18(1)

c-MYC oncogene is frequently deregulated by amplification in colon adenocarcinoma. c-MYC also activates telomerase by inducing expression of its catalytic subunit (h-TERT). Furthermore, telomerase activation plays a crucial role in tumorigenesis by s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::14aec8b8463cd0dd4975fbf5dd7392c6
https://pubmed.ncbi.nlm.nih.gov/23613397

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PTEN expression in non small cell lung carcinoma based on digitized image analysis

Autor: I, Panagiotou, E, Tsiambas, A C, Lazaris, N, Kavantzas, M, Konstantinou, P, Kalkandi, V, Ragkos, G E, Metaxas, D K, Roukas, G, Vilaras, E, Patsouris

Publikováno v: Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 17(4)

HER2 depended signalling pathway is dereg-ulated in a subset of non small cell lung carcinoma (NSCLC). The tumor suppressor gene PTEN (10q21) regulates the HER2/PI3K/Akt signalling pathway. Our aim was to evaluate PTEN protein expression in NSCLC bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8e820fcf9bbdb4072e0fdddf8b565a1
https://pubmed.ncbi.nlm.nih.gov/23335531

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Gene numerical imbalances in cytological specimens based on fluorescence/chromogenic in situ hybridization analysis

Autor: E, Tsiambas, A, Karameris, M, Lygeros, A E, Athanasiou, N S, Salemis, S, Gourgiotis, V, Ragkos, G E, Metaxas, G, Vilaras, E, Patsouris

Publikováno v: Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 17(3)

Design and development of novel targeted therapeutic strategies is an innovation in handling patients with solid malignancies including breast, colon, lung, headneck or even pancreatic and hepatocellular carcinoma. For a long time, immunohistocytoche

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::467caec5043f230b2718d27238ba5486
https://pubmed.ncbi.nlm.nih.gov/23033306

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Comparative study of the immunohistochemical expression of metalloproteinases 2, 7and 9between clearly invasive carcinomas and 'in situ' trophoblast invasion

Autor: Karameris A, Ioannidis I, Gakiopoulou H, Andreas C. Lazaris, Blerta Dimo, G. Vilaras, E. Patsouris

Publikováno v: Neoplasma. 57(1)

KEYWORDS: Matrix metalloproteinases (MMPs) are endopeptidases considered to participate in the transient invasive property of trophoblastic cells during embryo implantation and placentation. The same molecules play an important role in the invasive a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f9b0d300d3f98ac85d4a9914b01350
https://pubmed.ncbi.nlm.nih.gov/19895168

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720 Simultaneous HER2/neu and PTEN deregulation correlates with aggressive phenotype in hepatocellular carcinoma: a tissue microarray analysis

Autor: Spyridon P. Dourakis, L. Manaios, E. Patsouris, A. Karameris, G. Alexandrakis, G. Vilaras, E. Tsiambas

Publikováno v: European Journal of Cancer Supplements. 8:182

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::187fcfe6fff57406dc8748c2b49df2a2
https://doi.org/10.1016/s1359-6349(10)71517-2

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Morphometric study of immunohistochemical expression of topoisomerase IIa and p16 correlating with molecular detection of chromosome 17 and 9 instability, in pancreatic adenocarcinoma, using Tissue Microarrays application

Autor: E. Thanopoulou, G. Vilaras, A. Stamatelopoulos, Andreas Karameris, Evangelos Tsiambas

Publikováno v: Journal of Clinical Oncology. 23:4100-4100

4100 Background: Aberrations of chromosome 17 and 9 are common genetic events in many cancers including pancreatic adenocarcinoma. Topoisomerase IIa (17q21) is a nucleic enzyme, which affect the to...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5736555e8e6a56984914a20e17673d19
https://doi.org/10.1200/jco.2005.23.16_suppl.4100

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Tissue microarrays application in non-small cell lung carcinoma: Morphometric study of immunohistochemical expression of topoisomerase IIa correlating with molecular detection of the specific gene alterations and chromosome 17 instability

Autor: A. Stamatelopoulos, Andreas Karameris, Evangelos Tsiambas, G. Vilaras, E. Thanopoulou, Demosthenes Bouros

Publikováno v: Journal of Clinical Oncology. 23:9648-9648

9648 Background: Aberrations of chromosome 17 are common in many cancers including NSCLC. Topoisomerase family which includes Topo I (20q11), Topo IIa (17q21) and Topo IIb (3p24) is a class of enzy...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf3ab1df723182dd9d56c03632815f21
https://doi.org/10.1200/jco.2005.23.16_suppl.9648

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Akademický článek

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