Zobrazeno 1 - 10
of 502
pro vyhledávání: '"G, Trevino"'
Autor:
Song Han, Gerik W. Tushoski-Alemán, Peiyi Zhang, Guangrong Zheng, Daohong Zhou, Zhiguang Huo, Jonathan Licht, Thomas J. George, Carmen Allegra, Jose G. Trevino, Steven J. Hughes
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 59, Iss , Pp 101070- (2025)
Oncogenic KRAS signaling plays a critical role in pancreatic ductal adenocarcinoma (PDAC) biology. Recent studies indicate that the combination of MEK and BCL-xL inhibition is synthetically lethal and holds promise for some types of solid cancers, ho
Externí odkaz:
https://doaj.org/article/191df517e9ab4a0b927c1c49c80b247d
Autor:
Andrea N. Riner, Kelly M. Herremans, Vignesh Vudatha, Song Han, Xufeng Qu, Jinze Liu, Nitai Mukhopadhyay, Devon C. Freudenberger, Thomas J. George, Sarah M. Judge, Andrew R. Judge, Steven J. Hughes, Jose G. Trevino
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 1, Pp 149-158 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is highly associated with cachexia and weight loss, which is driven by the tumour's effect on the body. Data are lacking on differences in these metrics based on PDAC anatomic location. We h
Externí odkaz:
https://doaj.org/article/8b79d152af8740b48f6cb1720b637f74
Autor:
Pei-Ying Wu, Michelle Van Scoyk, Stephanie S. McHale, Chu-Fang Chou, Gregory Riddick, Kamran Farouq, Bin Hu, Vita Kraskauskiene, Jennifer Koblinski, Charles Lyons, Arjun Rijal, Vignesh Vudatha, Dongyu Zhang, Jose G. Trevino, Rachit D. Shah, Patrick Nana-Sinkam, Yong Huang, Shwu-Fan Ma, Imre Noth, Chanita Hughes-Halbert, Victoria L. Seewaldt, Ching-Yi Chen, Robert A. Winn
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108858- (2024)
Summary: Lung cancer is the third most common cancer with Black/AA men showing higher risk and poorer outcomes than NHW men. Lung cancer disparities are multifactorial, driven by tobacco exposure, inequities in care access, upstream health determinan
Externí odkaz:
https://doaj.org/article/2b1b617e9e464c16a2b0c6f8fca1416f
Autor:
Brian K. Sparkman, Janina Pearce, Katherine Klein, Michael Idowu, Koorosh Askari, Leopoldo J. Fernandez, Jose G. Trevino, Stephanie A. Sullivan, Devin T. Miller, Leslie M. Randall
Publikováno v:
Gynecologic Oncology Reports, Vol 51, Iss , Pp 101306- (2024)
Externí odkaz:
https://doaj.org/article/02a76c11bde2449ab9ec28c41a4fadb7
Autor:
Gerik W Tushoski-Alemán, Kelly M Herremans, Patrick W Underwood, Ashwin Akki, Andrea N Riner, Jose G Trevino, Song Han, Steven J Hughes
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297325 (2024)
BackgroundPancreatic ductal adenocarcinomas (PDAC) have heterogeneous tumor microenvironments relatively devoid of infiltrating immune cells. We aimed to quantitatively assess infiltrating CD3+ and CD8+ lymphocytes in a treatment-naïve patient cohor
Externí odkaz:
https://doaj.org/article/f09d8e56361249bc9e2342aa74cff5e4
Autor:
Dongyu Zhang, Amit Kumar, Praveen Bhoopathi, Anjan K Pradhan, Santanu Maji, Padmanabhan Mannangatti, Jolene J Windle, Mark A Subler, Vignesh Vudatha, Jose G Trevino, Esha Madan, Azeddine Atfi, Devanand Sarkar, Rajan Gogna, Swadesh K Das, Luni Emdad, Paul B Fisher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)
Background Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer without effective therapies and with poor prognosis, causing 7% of all cancer-related fatalities in the USA. Considering the lack of effective therapies for this aggressive ca
Externí odkaz:
https://doaj.org/article/9f08c95d77bc4a62afb9ec4fb457d6e4
Autor:
Kelly M. Herremans, Andrea N. Riner, Miles E. Cameron, Kelley L. McKinley, Eric W. Triplett, Steven J. Hughes, Jose G. Trevino
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Pancreatic cancer is a deadly disease with limited diagnostic and treatment options. Not all populations are affected equally, as disparities exist in pancreatic cancer prevalence, treatment and outcomes. Recently, next-generation sequencing
Externí odkaz:
https://doaj.org/article/e4cf8913392a4a998482830b4459af2c
Autor:
Miles E. Cameron, Patrick W. Underwood, Iverson E. Williams, Thomas J. George, Sarah M. Judge, Joshua F. Yarrow, Jose G. Trevino, Andrew R. Judge
Publikováno v:
Cancer Medicine, Vol 11, Iss 1, Pp 50-60 (2022)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest of all common malignancies. Treatment is difficult and often complicated by the presence of cachexia. The clinical portrait of cachexia contributes to the poor prognosis experien
Externí odkaz:
https://doaj.org/article/7670238a22ff4d2688bc8b0af8d4a791
Autor:
Thomas G. Biel, Svetlana Petrovskaya, Francesca Mascia, Tongzhong Ju, Lola Fashoyin-Aje, Kelly M. Herremans, Andrea N. Riner, Patrick W. Underwood, Michael H. Gerber, Martha Donoghue, Jose G. Trevino, V. Ashutosh Rao
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
In pancreatic cancer clinical trials, Black patients are under-represented while having higher morbidity and mortality rates as compared to other racial groups. Multiple factors, including socioeconomic and lifestyle factors may contribute to this di
Externí odkaz:
https://doaj.org/article/7d78001b4d024ea098ffacad19dadd38
Autor:
Kelly M. Herremans, Andrea N. Riner, Angel M. Charles, Jeremy A. Balch, Vignesh Vudatha, Devon C. Freudenberger, Ibrahim Nassour, Steven J. Hughes, Jose G. Trevino, Tyler J. Loftus
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/2043b47a19954aeb9da384a43df21094