Zobrazeno 1 - 10
of 265
pro vyhledávání: '"G, Skuza"'
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 58(2)
The problem of drug-resistant depression indicates a strong need for alternative antidepressant therapies. In our earlier papers we described synergistic, antidepressant-like effects of a combination of imipramine (IMI) and amantadine (AMA) in the fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19af39a98a7e5bec4f4aab998276e5b3
https://pubmed.ncbi.nlm.nih.gov/17622693
https://pubmed.ncbi.nlm.nih.gov/17622693
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 57(2)
Data acquired to date show that some sigma receptor ligands reveal "antidepressant-like" activity in the forced swim test in mice and rats. Moreover, our preliminary results suggested that joint administration of sigma receptor ligands and amantadine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83753e1a121cf6a013ca824c855958a2
https://pubmed.ncbi.nlm.nih.gov/16845227
https://pubmed.ncbi.nlm.nih.gov/16845227
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 56(4)
Recent studies indicate a role of the brain-derived neurotrophic factor (BDNF) in the pathophysiology of depression, as well as in the mechanism of action of antidepressant drugs (ADs). It has been shown that serum BDNF levels are decreased in depres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f15e2a7c4a4742303a972f9e588b1b71
https://pubmed.ncbi.nlm.nih.gov/16391422
https://pubmed.ncbi.nlm.nih.gov/16391422
Autor:
G. Skuza, K. Wedzony
Publikováno v:
Pharmacopsychiatry. 37
Sigma (sigma) receptors, first defined as a subclass of opioid receptors, later confounded with the high affinity phencyclidine (PCP) binding sites, now are regarded as unique binding sites, distinct from opiate and PCP receptors, and related to high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27cd3f6079fa2d2d94b9061249ae3c64
https://pubmed.ncbi.nlm.nih.gov/15547784
https://pubmed.ncbi.nlm.nih.gov/15547784
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 56(1)
Major depression is frequently associated with the hyperactivity of the hypothalamic-pituitary-adrenocortical axis, and glucocorticoid synthesis inhibitors have been shown to exert antidepressant action. The aim of the present study was to examine th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec5f67b8b540f1e83a6cfa46da67a362
https://pubmed.ncbi.nlm.nih.gov/15795475
https://pubmed.ncbi.nlm.nih.gov/15795475
Publikováno v:
Polish journal of pharmacology. 56(5)
The aim of the present study was to examine a potential anxiolytic- and antidepressant-like action of (+)-7-hydroxy-2-(di-n-propylamino)tetralin hydrobromide (7-OH-DPAT), a preferential dopamine D(3) receptor agonist, and N-{4-[4-(2-methoxyphenyl)-1-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::810fa1c823e3c947b795dada48f500f5
https://pubmed.ncbi.nlm.nih.gov/15591639
https://pubmed.ncbi.nlm.nih.gov/15591639
Autor:
G, Skuza, W, Kolasiewicz
Publikováno v:
Polish journal of pharmacology. 53(5)
The obtained results indicate that SA4503, a selective sigma1 receptor agonist, given repeatedly (but not acutely) enhanced the effects of phenylephrine, alpha1-adrenoceptor agonist, and clonidine (stimulating the postsynaptic alpha1-adrenoceptors at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96accec4547df3715652dc8f102bfe59
https://pubmed.ncbi.nlm.nih.gov/11990076
https://pubmed.ncbi.nlm.nih.gov/11990076
Publikováno v:
Polish journal of pharmacology. 53(6)
Previous studies have shown that antidepressant drugs with different pharmacological profiles, administered repeatedly, increase the locomotor hyperactivity induced by various dopaminomimetics, among others by (+/-)7-hydroxydipropylaminotetralin (7-O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a4ffe83c2b0a2d408f8334427ba4e4a
https://pubmed.ncbi.nlm.nih.gov/11985330
https://pubmed.ncbi.nlm.nih.gov/11985330
Autor:
G, Skuza
Publikováno v:
Polish journal of pharmacology. 52(4)
The obtained results indicate that joint administration of CGP 37849, a competitive NMDA receptor antagonist, and SA4503, a sigma1 (sigma1) receptor agonist or DTG, sigma 1/2 receptor agonist, evoked anticataleptic effect at doses which were ineffect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d697974690439d40a0817f8b737c4ff4
https://pubmed.ncbi.nlm.nih.gov/11345488
https://pubmed.ncbi.nlm.nih.gov/11345488
Autor:
G, Skuza
Publikováno v:
Polish journal of pharmacology. 51(6)
It has been hypothesized that some of negative effects exerted by cocaine are mediated via sigma (sigma) receptors. This report demonstrates the effects of selective sigma ligands, panamesine, DTG, rimcazole and SA 4503, on the cocaine-induced convul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50a7e1b4e567e04a954bd5ec322025fe
https://pubmed.ncbi.nlm.nih.gov/10817525
https://pubmed.ncbi.nlm.nih.gov/10817525