Zobrazeno 1 - 10 of 51 pro vyhledávání: '"G, Rucci"'
1
Flavone antagonists bind competitively with 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD) to the aryl hydrocarbon receptor but inhibit nuclear uptake and transformation
Autor: E C, Henry, A S, Kende, G, Rucci, M J, Totleben, J J, Willey, S D, Dertinger, R S, Pollenz, J P, Jones, T A, Gasiewicz
Publikováno v: Molecular pharmacology. 55(4)
Previous analyses suggested that potent aryl hydrocarbon receptor (AhR) antagonists were planar, with a lateral electron-rich center. To further define structural requirements and mechanism for antagonism, ten additional flavone derivatives were synt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b146e0e03ced2e31023a5d4e44737371
https://pubmed.ncbi.nlm.nih.gov/10101030
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2
Purification to homogeneity of the heteromeric DNA-binding form of the aryl hydrocarbon receptor from rat liver
Autor: E C, Henry, G, Rucci, T A, Gasiewicz
Publikováno v: Molecular pharmacology. 46(6)
The aryl hydrocarbon receptor (AhR) is a transcriptional enhancer that is activated by the binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related toxic xenobiotics, as well as some naturally occurring compounds. Ligand binding initiates 1)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3e5e0c49184dc1742b613d80aa01044d
https://pubmed.ncbi.nlm.nih.gov/7808420
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3
Akademický článek
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4
Preparation and x-ray crystal structure of (benzonitrile)tris(triphenylphosphorane)nickel(0)
Autor: M. Calcaterra, C. Benedicenti, G. Rucci, I. W. Bassi
Publikováno v: Journal of Organometallic Chemistry. 117:285-295
Treatment of triphenylphosphine with bis(cycloocta-1,5-diene)nickel(0) in toluene followed by addition of benzonitrile gave two nickel(O) complexes. When the nickel/phosphine ratio was 1 : 3 the (benzonitrile)tris(triphenylphosphorane)- nickel(0) com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b99641bfb693a284e544551ad8b30252
https://doi.org/10.1016/s0022-328x(00)91899-0
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5
X-ray crystal structure of the clathrate compound tetrakis[(benzonitrile)(triphenylphosphorane)nickel(0)] · 2 toluene · ~1 n-hexane · ~1 cycloocta-1,5-diene
Autor: R. Intrito, M. Calcaterra, C. Benedicenti, C. Santini, I. W. Bassi, G. Rucci
Publikováno v: Journal of Organometallic Chemistry. 144:225-237
The preparation and the chemical properties of the clathrate compound tetrakis[(benzonitrile)(triphenylphosphorane)nickel(0)] · 2 toluene · ~1 n-hexane · ~1 cycloocta-1,5-diene are described. The crystal and molecular structure of this compound we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6edaa04f8dd8dd8682f54e3c22530cfe
https://doi.org/10.1016/s0022-328x(00)84165-0
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6
Akademický článek
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8
Distribution, excretion, and metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6J, DBA/2J, and B6D2F1/J mice
Autor: T A, Gasiewicz, L E, Geiger, G, Rucci, R A, Neal
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 11(5)
The strains of mice, C57BL/6J, DBA/2J, and B6D2F1/J, have been used as models to study the mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The distribution, excretion, and metabolism of this compound was studied in male C57BL/6J, D
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ebb78a32c650f162412985b15abfb7d8
https://pubmed.ncbi.nlm.nih.gov/6138222
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9
Changes in hamster hepatic cytochrome P-450, ethoxycoumarin O-deethylase, and reduced NAD(P): menadione oxidoreductase following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Partial dissociation of temporal and dose-response relationships from elicited toxicity
Autor: T A, Gasiewicz, G, Rucci, E C, Henry, R B, Baggs
Publikováno v: Biochemical pharmacology. 35(16)
The temporal and dose-related characteristics of hepatic enzymes induced in the hamster by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) were examined. Male Syrian golden hamsters received a single intraperitoneal injection of TCDD at a dose of 0-500 mi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd99092e9f0453314f1143fd64f8456c
https://pubmed.ncbi.nlm.nih.gov/3091031
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10
Cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Evidence for a homologous nature among various mammalian species
Autor: T A, Gasiewicz, G, Rucci
Publikováno v: Molecular pharmacology. 26(1)
The presence and properties of the Ah receptor were examined in the guinea pig, rat, hamster, monkey, and three different strains of mice. These species and strains have demonstrated differences in sensitivity and variability of response to 2,3,7,8-t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b75b464ef514022a079d7a62308b2c69
https://pubmed.ncbi.nlm.nih.gov/6087120
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