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pro vyhledávání: '"G, Rappa"'
Akademický článek
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Publikováno v:
Cancer Gene Therapy. 15:605-615
Despite recent technical improvements in surgical excision techniques and adjuvant radio- and chemotherapy, the clinical outcome of patients with grade IV astrocytoma (glioblastoma) remains very poor, with a median survival of less than 12 months. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1925bcb023753955aaeb520563136bc
https://doi.org/10.1038/cgt.2008.23
https://doi.org/10.1038/cgt.2008.23
Akademický článek
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Autor:
Zhong-Gao Wang, Clemente Crisci, Hugh G. Rappa, Carlo G. Massimo, Eduardo A. Cruz Guadrón, Vazgen R. Artounian
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 120(4):818-820
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7fa12f5473a534efb6923fd1e2abe4
Autor:
J R, Murren, S A, DiStasio, A, Lorico, A, McKeon, E G, Zuhowski, M J, Egorin, A C, Sartorelli, G, Rappa
Publikováno v:
Cancer journal (Sudbury, Mass.). 6(4)
The coumarin antibiotic novobiocin potentiates the activity of etoposide (VP-16) in vitro by increasing intracellular accumulation of VP-16. The drug efflux pump inhibited by novobiocin appears to be distinct from both of the major proteins associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60b0b0520f9afd4330aec3e315992bdb
https://pubmed.ncbi.nlm.nih.gov/11038146
https://pubmed.ncbi.nlm.nih.gov/11038146
Publikováno v:
Anti-cancer drug design. 15(2)
We have previously reported that novobiocin potentiates the cytotoxic activity of etoposide (VP-16) and teniposide (VM-26) in a number of experimental tumor cell lines by inhibition of the efflux of the epipodophyllotoxins by an ATP-requiring transpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::638a973c5515b0da56ea7b6581c3f15a
https://pubmed.ncbi.nlm.nih.gov/10901300
https://pubmed.ncbi.nlm.nih.gov/10901300
Publikováno v:
Biochemical pharmacology. 58(4)
Growing interest in the MRP (multidrug resistance protein) gene stems from its importance in multidrug resistance to chemotherapy, its possible use in gene therapy, and its relationship with the glutathione system. The recent generation of mrp gene k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0ec7b9fb0fc579449736ecef9bc53c5
https://pubmed.ncbi.nlm.nih.gov/10413292
https://pubmed.ncbi.nlm.nih.gov/10413292
Publikováno v:
Anticancer research. 17(5A)
A mouse leukemia L1210 cell line, denoted MQ-580, that was selected for resistance to the ribonucleotide reductase inhibitor, 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone (MAIQ), in addition to having altered properties at the ribonucleoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1a2b8856d35c9610466ff902341c24b
https://pubmed.ncbi.nlm.nih.gov/9413147
https://pubmed.ncbi.nlm.nih.gov/9413147
Publikováno v:
Cancer research. 57(23)
The mrp (multidrug resistance protein) gene has been associated with the multidrug resistance of cancer cells in vitro and in vivo. To gain information on its physiological role, embryonic stem cells were used to generate mice homozygous for a disrup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a201a755fe2a47edcc86db72977ae0c2
https://pubmed.ncbi.nlm.nih.gov/9393741
https://pubmed.ncbi.nlm.nih.gov/9393741