Zobrazeno 1 - 10
of 281
pro vyhledávání: '"G, Purdy"'
Autor:
Rosamund Oates, Jessica G. Purdy
This book provides a new perspective on book history by exploring communities created by the production and consumption of printed material. Essays by leading scholars explore the connections between writers, printers, booksellers and readers and exa
Autor:
Rakesh Ganji, Joao A. Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph S. Clemen, Conrad C. Weihl, John G. Purdy, Steve P. Gygi, Malavika Raman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Inter-organellar contacts are hubs for several critical cellular processes, such as lipid synthesis. Here Ganji et al. show that the p97-UBXD8 complex modulates contacts by regulating membrane lipid composition and saturation.
Externí odkaz:
https://doaj.org/article/ec8b699c1b3c422ea6b756578b81cfd6
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
HCMV is a common herpesvirus that establishes lifelong persistent infections. While infection is asymptomatic in most people, HCMV causes life-threatening illnesses in immunocompromised people, including transplant recipients and cancer patients.
Externí odkaz:
https://doaj.org/article/41ec593071d94836a09659198b2ad39a
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Viruses, including human cytomegalovirus (HCMV), reprogram cellular metabolism using host metabolic regulators to support virus replication. Alternatively, in response to infection, the host can use metabolism to limit virus replication.
Externí odkaz:
https://doaj.org/article/7daaedca64ee424cb0021770133620c6
Publikováno v:
eLife, Vol 9 (2020)
Human Cytomegalovirus (HCMV) infects over half the world's population, is a leading cause of congenital birth defects, and poses serious risks for immuno-compromised individuals. To expand the molecular knowledge governing virion maturation, we analy
Externí odkaz:
https://doaj.org/article/a071ccccecbd48ac9eef34aa58b408e5
Publikováno v:
Case Reports in Infectious Diseases, Vol 2020 (2020)
Hydroxychloroquine has gained popularity as a potential preventative and treatment of COVID-19 pneumonia due to its in vitro activity against the virus. These three cases of COVID-19 pneumonia of varying severities occurred in the setting of chronic
Externí odkaz:
https://doaj.org/article/7ebe40e2d0c84fd0a9ffddc8d54fb2b7
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007830 (2019)
Externí odkaz:
https://doaj.org/article/3bdc641672654c7bb0b472e8443d05d6
Akademický článek
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Publikováno v:
Cell Reports, Vol 10, Iss 8, Pp 1375-1385 (2015)
Human cytomegalovirus (HCMV) infection rewires host-cell metabolism, upregulating flux from glucose into acetyl-CoA to feed fatty acid metabolism, with saturated very-long-chain fatty acids (VLFCAs) required for production of infectious virion progen
Externí odkaz:
https://doaj.org/article/886c32da42a945d28e26eda335e05966
Autor:
Rakesh Ganji, Joao A. Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph S. Clemen, Conrad C. Weihl, John G. Purdy, Steve P. Gygi, Malavika Raman
The intimate association between the endoplasmic reticulum (ER) and mitochondrial membranes at ER-mitochondria contact sites serves as a platform for several critical cellular processes, in particular lipid synthesis. Enzymes involved in lipid biosyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d15a5c58f7e50eecde8b3da3932ce829
https://doi.org/10.1101/2021.12.08.471763
https://doi.org/10.1101/2021.12.08.471763