Zobrazeno 1 - 10
of 226
pro vyhledávání: '"G, Perides"'
Publikováno v:
Journal of Neurochemistry. 83:828-836
Based on the critical role of actin in the maintenance of synaptic function, we examined whether expression of familial beta-amyloid precursor protein APP-V642I (IAPP) or mutant presenilin-1 L286V (mPS1) affects actin polymerization in rat septal neu
Publikováno v:
The Journal of Cell Biology. 133:381-390
Mental retardation, hydrocephalus, and agenesis of the corpus callosum are observed both in fetal alcohol syndrome (FAS) and in children with mutations in the gene for the cell adhesion molecule L1. We studied the effects of ethanol on cell-cell adhe
Publikováno v:
Biochemical Journal. 312:377-384
Glial hyaluronate-binding protein (GHAP) is a 60 kDa glycoprotein with an amino acid sequence identical to that of the hyaluronate-binding region of versican, a large fibroblast aggregating proteoglycan found in the brain. Both GHAP and versican were
Publikováno v:
Neuroscience Letters. 187:21-24
Possible neuroprotective actions of osteogenic protein-1 (OP-1) were evaluated in a rat model of cerebral hypoxia/ischemia. Intraperitoneal injection of 50 micrograms of OP-1 prior to bilateral carotid ligation and transient hypoxia in 12-day-old rat
Publikováno v:
Journal of Biological Chemistry. 269:9304-9309
Gestational exposure to ethanol causes defects in neuronal migration, fasciculation, and synaptogenesis, developmental events that depend on the patterned expression and function of cell adhesion molecules (CAMs). Recombinant human osteogenic protein
Publikováno v:
Journal of Biological Chemistry. 269:765-770
The transforming growth factor-beta (TGF-beta) superfamily plays a role in embryogenesis and regeneration. We have reported that osteogenic protein-1 (OP-1) promotes cell aggregation and induces the expression of the neural cell adhesion molecules N-
Autor:
G. Perides, Alessandro Tona
Publikováno v:
Restorative neurology and neuroscience. 5(2)
Silicone regeneration chambers prefilled with sodium hyaluronate (HA) gels of different molecular weight (MW) and at different concentrations were used to tubulize the transected rat sciatic nerve. After two weeks, the tissue cables bridging the seve
Publikováno v:
Journal of Biological Chemistry. 268:25197-25205
Osteogenic protein-1 (OP-1) is a member of the TGF-beta superfamily that is expressed in the nervous system. We recently showed that human recombinant osteogenic protein-1 (hOP-1) strongly promotes the aggregation of dividing neuroblastoma x glioma h
Publikováno v:
Journal of Histochemistry & Cytochemistry. 41:593-599
Using a glial hyaluronate-binding protein as a probe, monoclonal antibodies against versican and ABC digested chondroitin sulfate proteoglycans, and polyclonal antibodies against laminin, we localized these extracellular matrix (ECM) components in th
Publikováno v:
Journal of Neuroscience Research. 34:97-106
The localization of versican, a large hyaluronatebinding fibroblast proteoglycan, was studies in rat prenatal and postnatal development. In adult rat white matter and cerebellum, the distribution of versican was identical to that previously reported