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Identification of a novel gp100/pMel17 peptide presented by HLA-A*6801 and recognized on human melanoma by cytolytic T cell clones

Autor: G. Parmiani, Claudia Vegetti, A. Anichini, Serena Pellegatta, M. Sensi, G. Nicolini

Publikováno v: Tissue Antigens. 59:273-279

Melanoma-associated peptides recognized by cytolytic T lymphocytes (CTL) in the context of several histocompatibility leukocyte antigens (HLA) are required for the development of specific immunotherapies. Using a transient transfection assay into COS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3300748f5884be719c2aa72b1892d015
https://doi.org/10.1034/j.1399-0039.2002.590404.x

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Tumour immunotherapy: the adjuvant treatment of the21st century?

Autor: G Parmiani, P.J.K. Kuppen, A.J.A Bremers

Publikováno v: European Journal of Surgical Oncology (EJSO). 26:418-424

In the course of a century, tumour immunology has revealed a picture of a very complex immune system involving the recognition and eradication of malignancies. Many tumours evade the immune system, and understanding of tumour escape mechanisms is the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e39de3e61f969b1c45f4c8953ffd70
https://doi.org/10.1053/ejso.1999.0908

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Genes involved in melanoma

Autor: M. Castellano, G. Parmiani

Publikováno v: Melanoma Research. 9:421-432

Melanoma is the most aggressive of the skin cancers and its prognosis is often poor. The only known environmental risk factor for this tumour is ultraviolet light exposure. This fact together with the existence of melanoma-prone families has prompted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59305c6069e9deb420080d13ddf0b08d
https://doi.org/10.1097/00008390-199910000-00001

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Novel HLA-Cw8-Restricted T Cell Epitopes Derived from Tyrosinase-Related Protein-2 and gp100 Melanoma Antigens

Autor: C, Castelli, P, Tarsini, A, Mazzocchi, F, Rini, L, Rivoltini, F, Ravagnani, F, Gallino, F, Belli, G, Parmiani

Publikováno v: The Journal of Immunology. 162:1739-1748

The identification of T cell epitopes presented by alternative HLA-B and -C alleles may provide a means to counteract the tumor escape mechanism based on the selection of tumor cells no longer susceptible to HLA-A-restricted T cell recognition. Sever

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff208bed234ac2c13ab4a639eb0c0dc
https://doi.org/10.4049/jimmunol.162.3.1739

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Future perspectives in specific immunotherapy of melanoma

Autor: G. Parmiani

Publikováno v: European Journal of Cancer. 34:42-47

With the discovery of T-cell recognised tumour-associated antigens (TAAs), interest in specific immunotherapy for treatment of malignancies has increased substantially. The majority of studies investigating TAAs have focused on melanoma-associated an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409df4dd2fc04fad43e95a87551a7c1f
https://doi.org/10.1016/s0959-8049(97)10164-2

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Treatment of recurrent in transit metastases from cutaneous melanoma by isolation perfusion in extracorporeal circulation with interleukin-2 and lymphokine activated killer cells. A pilot study

Autor: F. Belli, F. Arienti, L. Rivoltini, M. Santinami, L. Mascheroni, A. Prada, M. Ammatuna, E. Marchesi, G. Parmiani, N. Cascinelli, M. Vaglini

Publikováno v: Scopus-Elsevier

Chemoresistant melanoma cells are known to be susceptible in vitro to lymphokine activated killer (LAK) cells. To obtain a high LAK/tumour cell ratio in vivo and avoid systemic toxicity due to interleukin-2 (IL-2), we used IL-2 plus LAK cells in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7f3b1deb39fed6ac7c876c720b86de
https://doi.org/10.1097/00008390-199211000-00007

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Identification of a novel gp100/pMel17 peptide presented by HLA-A*6801 and recognized on human melanoma by cytolytic T cell clones

Autor: M, Sensi, S, Pellegatta, C, Vegetti, G, Nicolini, G, Parmiani, A, Anichini

Publikováno v: Tissue antigens. 59(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::94a606ae7ddd4e9fcd6518299f556b41
https://pubmed.ncbi.nlm.nih.gov/12135425

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