Zobrazeno 1 - 10
of 501
pro vyhledávání: '"G, Mayor"'
Autor:
Ariel R. Topletz-Erickson, JoAl G. Mayor, Hsu-Tai Liu, Layth I. Abdulrasool, Christopher J. Endres
Publikováno v:
Drugs in R&D, Vol 23, Iss 4, Pp 411-419 (2023)
Abstract Background and Objective Tucatinib is a selective tyrosine kinase inhibitor of the human epidermal growth factor receptor 2 (HER2) approved to treat metastatic HER2-positive breast and colorectal cancers. The International Council for Harmon
Externí odkaz:
https://doaj.org/article/7a4ad461bb6c4392b531e81c99da3f67
Autor:
Ariel R, Topletz-Erickson, Anthony J, Lee, JoAl G, Mayor, Hao, Sun, Layth I, Abdulrasool, Evelyn L, Rustia, Luke N, Walker, Christopher J, Endres
Publikováno v:
Clinical Pharmacokinetics. 61:1761-1770
Tucatinib, a highly selective tyrosine kinase inhibitor of the human epidermal growth factor receptor 2 (HER2) approved for HER2-positive metastatic breast cancer, is cleared by hepatic metabolism and subsequent biliary excretion. Liver disease can a
Autor:
Erik van den Elsen, Lindsay C. Stringer, Cecilia De Ita, Rudi Hessel, Sonia Kéfi, Florian D. Schneider, Susana Bautista, Angeles G. Mayor, Mara Baudena, Max Rietkerk, Alejandro Valdecantos, Victoriano R. Vallejo, Nichola Geeson, C. Jane Brandt, Luuk Fleskens, Lia Hemerik, Panos Panagos, Sandra Valente, Jan J. Keizer, Gudrun Schwilch, Matteo Jucker Riva, Diana Sietz, Michalakis Christoforou, Diofantos G. Hadjimitsis, Christiana Papoutsa, Giovanni Quaranta, Rosanna Salvia, Ioannis K. Tsanis, Ioannis Daliakopoulos, Heleen Claringbould, Peter C. de Ruiter
Publikováno v:
Frontiers in Ecology and Evolution, Vol 8 (2020)
One of the most challenging issues in Mediterranean ecosystems to date has been to understand the emergence of discontinuous changes or catastrophic shifts. In the era of the 2030 Sustainable Development Goals, which encompass ideas around Land Degra
Externí odkaz:
https://doaj.org/article/66dd9d444be44b00a4fa782a76d2cd01
Bare-soil connectivity and vegetation cover have proven to be good indicators of dryland function. The two properties are closely correlated and reflect the combined role of both the amount and spatial distribution of vegetation, making it difficult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5be39c19355b9a7f9f84d15ba14bee9
https://doi.org/10.5194/egusphere-egu23-11363
https://doi.org/10.5194/egusphere-egu23-11363
Publikováno v:
Atmosphere, Vol 11, Iss 9, p 973 (2020)
Convective ensembles promise to increase forecast accuracy while at the same time providing information on the probability of the forecast. A vast number of different methods of ensemble creation have been developed over time. Here, initial condition
Externí odkaz:
https://doaj.org/article/5945c2c0984747b4ab2d702eeae8754d
Autor:
Ariel Topletz-Erickson, Anthony Lee, Evelyn L. Rustia, Hao Sun, JoAl G. Mayor, Layth I. Abdulrasool, Luke Walker, Christopher J. Endres
Publikováno v:
Clinical pharmacokinetics. 61(10)
Tucatinib is approved for treatment of human epidermal growth factor receptor 2-positive metastatic breast cancer. Understanding potential drug-drug interactions (DDIs) informs proper dosing when co-administering tucatinib with other therapies. The a
Autor:
Valentin Wendling, Christophe Peugeot, Angeles G Mayor, Pierre Hiernaux, Eric Mougin, Manuela Grippa, Laurent Kergoat, Romain Walcker, Sylvie Galle, Thierry Lebel
Publikováno v:
Environmental Research Letters, Vol 14, Iss 10, p 105005 (2019)
The Sahel (a semi-arid fringe south of the Sahara) experienced a long and prolonged drought from the 1970s to the mid-1990s, with a few extremely severe episodes that strongly affected ecosystems and societies. Long-term observations showed that surf
Externí odkaz:
https://doaj.org/article/ee9787e911bc4b989f31bf5b4c4456b1
Autor:
Ariel R. Topletz-Erickson, Anthony Lee, Vineet Kumar, Michelle Ubowski, JoAl G. Mayor, Layth I. Abdulrasool, Clark M. Henderson, Joseph A. Ware, Christopher J. Endres
Publikováno v:
Cancer Research. 83:5060-5060
Background: Oxaliplatin (OX)-containing regimens are frequently utilized to treat gastrointestinal (GI) cancers. OX is eliminated predominately via urinary excretion (GFR and active tubular secretion). The contribution of active transport via OCT2 an
Autor:
Mariam Fonseca-Hernández, Iryna Tereshchenko, Yandy G. Mayor, Arturo Figueroa-Montaño, Osvaldo Cuesta-Santos, Cesar Monzón
Publikováno v:
Atmosphere, Vol 9, Iss 7, p 243 (2018)
To study the air quality in the Guadalajara Metropolitan Area (GMA), concentrations of suspended particles (PM10) and ozone (O3) reported by eight monitoring stations were analyzed. Also, six commonly found types of synoptic situations (TSS) during 1
Externí odkaz:
https://doaj.org/article/3321586faddf4f97b195e9d81407b907
Autor:
Yandy G. Mayor, Michel D. S. Mesquita
Publikováno v:
Advances in Meteorology, Vol 2015 (2015)
This paper evaluates the sensitivity to cumulus and microphysics schemes, as represented in numerical simulations of the Weather Research and Forecasting model, in characterizing a deep convection event over the Cuban island on 1 May 2012. To this en
Externí odkaz:
https://doaj.org/article/8d8212037de4490fbc54cded17b88bf7