Zobrazeno 1 - 10
of 1 043
pro vyhledávání: '"G, Kok"'
Autor:
I. F. Schene, I. P. Joore, J. H. L. Baijens, R. Stevelink, G. Kok, S. Shehata, E. F. Ilcken, E. C. M. Nieuwenhuis, D. P. Bolhuis, R. C. M. van Rees, S. A. Spelier, H. P. J. van der Doef, J. M. Beekman, R. H. J. Houwen, E. E. S. Nieuwenhuis, S. A. Fuchs
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
While prime editing is a promising technique, some genomic sites remain difficult to edit. Here the authors present fluoPEER, fluorescent prime editing and enrichment reporter, to rank the efficiency of pegRNAs and prime editor variants.
Externí odkaz:
https://doaj.org/article/ff29147a3c594221b358c3489445515b
Autor:
Harm J. van der Horn, Sanne K. Meles, Jelmer G. Kok, Victor M. Vergara, Shile Qi, Vince D. Calhoun, Jelle R. Dalenberg, Jeroen C.W. Siero, Remco J. Renken, Jeroen J. de Vries, Jacoba M. Spikman, Hubertus P.H. Kremer, Bauke M. De Jong
Publikováno v:
NeuroImage: Clinical, Vol 34, Iss , Pp 103023- (2022)
Spinocerebellar ataxia type 3 (SCA3) is a rare genetic neurodegenerative disease. The neurobiological basis of SCA3 is still poorly understood, and up until now resting-state fMRI (rs-fMRI) has not been used to study this disease. In the current stud
Externí odkaz:
https://doaj.org/article/4b6f9c067d1a4fd9a8fd2570b28a093f
Autor:
Nicolette R. den Braver, Julia G. Kok, Joreintje D. Mackenbach, Harry Rutter, Jean-Michel Oppert, Sofie Compernolle, Jos W. R. Twisk, Johannes Brug, Joline W. J. Beulens, Jeroen Lakerveld
Publikováno v:
International Journal of Behavioral Nutrition and Physical Activity, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background Car driving is a form of passive transportation associated with higher sedentary behaviour, which is associated with morbidity. The decision to drive a car is likely to be influenced by the ‘drivability’ of the built environme
Externí odkaz:
https://doaj.org/article/c68c2e66ff9a4eecaae9abbfb9077858
Autor:
Jelmer G. Kok, Alexander Leemans, Laura K. Teune, Klaus L. Leenders, Martin J. McKeown, Silke Appel-Cresswell, Hubertus P. H. Kremer, Bauke M. de Jong
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Functional impairment of spatially distributed brain regions in Parkinson's disease (PD) suggests changes in integrative and segregative network characteristics, for which novel analysis methods are available. To assess underlying structural network
Externí odkaz:
https://doaj.org/article/c84724dd1f99448791013254f8e8b0cd
Autor:
G. A. Ten Hoor, G. M. Rutten, G. J. P. Van Breukelen, G. Kok, R. A. C. Ruiter, K Meijer, S. P. J. Kremers, F. J. M. Feron, R. Crutzen, A. M. J. W. Schols, G. Plasqui
Publikováno v:
International Journal of Behavioral Nutrition and Physical Activity, Vol 15, Iss 1, Pp 1-13 (2018)
Abstract Background Metabolic health in people with obesity is determined by body composition. In this study, we examined the influence of a combined strength exercise and motivational programme –embedded in the school curriculum– on adolescents
Externí odkaz:
https://doaj.org/article/17ed1086f0094bdd9771b5169253e41d
Autor:
T. Sauerwald, T. Baur, M. Leidinger, W. Reimringer, L. Spinelle, M. Gerboles, G. Kok, A. Schütze
Publikováno v:
Journal of Sensors and Sensor Systems, Vol 7, Pp 235-243 (2018)
For detection of benzene, a gas sensor system with metal oxide semiconductor (MOS) gas sensors using temperature-cycled operation (TCO) is presented. The system has been tested in two different laboratories at the concentration range from 0.5 up t
Externí odkaz:
https://doaj.org/article/7d7caba280654173ba86be0d0994fabf
Autor:
Sanne K. Meles, Jelmer G. Kok, Bauke M. De Jong, Remco J. Renken, Jeroen J. de Vries, Jacoba M. Spikman, Aaltje L. Ziengs, Antoon T.M. Willemsen, Harm J. van der Horn, Klaus L. Leenders, Hubertus P.H. Kremer
Publikováno v:
NeuroImage: Clinical, Vol 19, Iss , Pp 90-97 (2018)
Introduction: We aimed to uncover the pattern of network-level changes in neuronal function in Spinocerebellar ataxia type 3 (SCA3). Methods: 17 genetically-confirmed SCA3 patients and 16 controls underwent structural MRI and static resting-state [18
Externí odkaz:
https://doaj.org/article/cfa1543eb3cd48bdbeceddbc1335c461
Publikováno v:
eXPRESS Polymer Letters, Vol 11, Iss 10, Pp 799-808 (2017)
Various sugar-based methacrylate monomers have been prepared and randomly copolymerized with methyl methacrylate (MMA) using classical atom transfer radical polymerization (ATRP). Firstly, four different sugar-based methacrylates are synthesized by t
Externí odkaz:
https://doaj.org/article/65bf4df40cc74fc3ab6698e61e5919c5
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