Zobrazeno 1 - 10
of 398
pro vyhledávání: '"G, Kéri"'
Autor:
G Kéri, M Idei, Jenő Major, Mátyás G. Jakab, Jozsef Bocsi, Anna Tompa, Béla Szende, Rudolf Mihalik
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 465:61-68
Somatostatin receptors are supposed to be important in the regulation of apoptosis. In this study, we measured apoptosis occurring spontaneously, or induced by the synthetic somatostatin analogue, the peptide TT-232. We examined isolated human periph
Autor:
F, Hollósy, M, Idei, G, Csorba, E, Szabó, G, Bökönyi, A, Seprödi, G, Mészáros, B, Szende, G, Kéri
Publikováno v:
Anticancer research. 21(5)
The apoptosis-inducing effect of the triterpene saponins, namely, ursolic acid and its natural derivative, methyl-ursolate beta-D-glucoside on A431 human epidermoid carcinoma cells was studied. The cells treated with 5-50 microg/ml of ursolic acid re
Publikováno v:
British journal of pharmacology. 134(7)
1. Somatostatin (6.11 nmol kg(-1) i.p.) inhibited neurogenic plasma extravasation evoked by 1% mustard oil and non-neurogenic oedema induced by 5% dextran in the rat skin. 2. Cyclic synthetic octapeptide (TT-248 and TT-250) and heptapeptide (TT-232)
Autor:
T, Vántus, G, Kéri, Z, Krivickiene, M, Valius, A, Steták, S, Keppens, P, Csermely, P I, Bauer, G, Bökönyi, W, Declercq, P, Vandenabeele, W, Merlevede, J R, Vandenheede
Publikováno v:
Cellular signalling. 13(10)
TT-232 is a somatostatin analogue containing a five-residue ring structure. The present report describes TT-232-induced signalling events in A431 cells, where a 4-h preincubation with the peptide irreversibly induced a cell death program, which invol
Publikováno v:
European journal of biochemistry. 268(14)
The immunoreceptor tyrosine-based inhibitory motif (ITIM) of human type IIb Fcgamma receptor (FcgammaRIIb) is phosphorylated on its tyrosine upon co-clustering with the B cell receptor (BCR). The phosphorylated ITIM (p-ITIM) binds to the SH2 domains
Autor:
R E, Schwab, S, Froidevaux, S, Paku, M, Tejeda, B, Szende, A, Pap, C, Beglinger, A N, Eberle, G, Kéri
Publikováno v:
Anticancer research. 21(1A)
TT-232, a somatostatin analogue, induces apoptosis in various tumours. The aim of our study was to characterise its effect on human melanoma cells and tumours.Proliferation of seven melanoma cell lines was tested in vitro with the methylene blue test
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996). 108(1)
The mode of cytoprotective action of the monoamine oxydase B inhibitor (-)-deprenyl was studied using A-2058 human melanoma cells in culture. Serum deprivation caused apoptosis of the cultured cells, which could be decreased by administration of 10(-
Autor:
M, Kunvári, C, Páska, M, László, L, Orfi, I, Kövesdi, D, Eros, G, Bökönyi, G, Kéri, I, Gyurján
Publikováno v:
Acta pharmaceutica Hungarica. 69(5)
Tyrosine kinase inhibition and tumor growth inhibition activity of verbascoside and homoplantaginin are described. Both molecules proved to be equally significant inhibitors of isolated EGF-R tyrosine kinases, nevertheless their in vitro antiprolifer
Autor:
L, Orfi, F, Wáczek, M, Szabó, I, Kövesdi, G, Mészáros, M, Idei, A, Horváth, F, Hollósy, M, Mák, Z, Szegedi, B, Szende, G, Kéri, B, Noszál
Publikováno v:
Acta pharmaceutica Hungarica. 69(3)
A parallel combinatorial library of over sixteen hundred compounds has been designed and synthesized for the development of new potential peptidomimetic protein tyrosine kinase (PTK) inhibitor leads that is aimed for intervening with the substrate bi
Autor:
I, Mezô, J, Seprôdi, B, Vincze, I, Pályi, G, Kéri, Z, Vadász, G, Tóth, M, Kovács, M, Koppán, J E, Horváth, A, Kálnay, I, Teplán
Publikováno v:
Biomedical peptides, proteinsnucleic acids : structure, synthesisbiological activity. 2(2)
New chicken I GnRH agonists and antagonists have been synthesized and tested for their biological activities. The common feature of these analogs was that the molecules had a beta-L-aspartyl residue inserted in position 6. The agonist bound to the pi