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Autor:
V. Willeaume, P. Distefano, G. Huez, Jean Marie Ruysschaert, Abdelatif Elouahabi, Robert Fuks, Michel Vandenbranden
Publikováno v:
Biochemical and Biophysical Research Communications. 203:1622-1628
We describe here a new cationic amphiphile, N-t-butyl-N'-tetradecyl-3-tetradecylaminopropionamidine (diC14-amidine), which interacts with plasmid DNA and generates hydrophobic stable complexes resistant against DNase I. In partition experiments betwe
Publikováno v:
The Journal of Immunology. 146:1843-1848
The tumor necrosis factor (TNF) promoter and 3'-untranslated region (3'-UTR) each contain sequence elements that mediate a response to bacterial endotoxin. Although the promoter contains sequences that permit augmented TNF gene transcription in respo
Publikováno v:
European journal of biochemistry. 267(19)
TNF-alpha gene expression is regulated at transcriptional and post-transcriptional levels in mouse macrophages. The post-transcriptional regulation is mediated by the AU-rich element (ARE) located in the TNF-alpha mRNA 3' untranslated region (UTR), w
Publikováno v:
Cytogenetics and cell genetics. 87(1-2)
Publikováno v:
Journal of inflammation. 46(2)
Macrophage activation by lipopolysaccharide (LPS) results in the translational activation of tumor necrosis factor (TNF) mRNA. The initial phase of macrophage activation is followed by a refractory state called LPS tolerance characterized by an impai
Publikováno v:
Journal of inflammation. 46(1)
Tumor necrosis factor (TNF)-a gene expression can be induced primarily in cells of the monocyte-macrophage lineage by a variety of inducers, including lipopolysaccharides (LPS), phorbol esters, ultraviolet (UV) light, and viruses. In this paper, we a
Autor:
G. Huez, Paul Popper, Debora B. Farber, Jeff M. Bronstein, Paul E. Micevych, Claude G. Wasterlain
Publikováno v:
Brain research. 584(1-2)
The kindling model of epilepsy is associated with long-lasting changes in type II calmodulin kinase (CaM kinase) activity and immunoreactivity. In order to determine the mechanism of these alterations, we measured gene expression of CaM kinase using
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 144(8)
Recently, functional heterogeneity among Th cells has been recognized. Based on pattern of lymphokine secretion, two mutually exclusive subsets of CD4+ cells have been defined and designated Th1 (secreting IL-2 and IFN-gamma) and Th2 (secreting IL-4
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Interferon-induced 2–5A synthetases are probably involved in some antiviral actions of interferon. In human cells two different mRNAs (1.6, 1.8 kb long) coding for this protein are transcribed from the same gene and are produced by differential spl