Zobrazeno 1 - 10
of 57
pro vyhledávání: '"G, Hannum"'
Autor:
Lynn G. Hannum, Tianzeng Chen
Publikováno v:
The Journal of Immunology. 200:46.22-46.22
The pace of growth in populations over the age of 65 is increasing in the U.S. and worldwide, posing serious challenges for health care systems. Studies in both humans and mice have revealed evidence of dysregulation of innate immunity in older indiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee21f338cc217b67142c5cfdda2b0899
https://doi.org/10.4049/jimmunol.200.supp.46.22
https://doi.org/10.4049/jimmunol.200.supp.46.22
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 151:726-730
Multiple components of vertebrate immune systems have been shown to exhibit circadian fluctuations. While the zebrafish is currently generating a wealth of information on the molecular pacemakers that may control circadian rhythms, there have been no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e650b25143ac02c2902f4584b39659a7
https://doi.org/10.1016/j.cbpa.2008.08.030
https://doi.org/10.1016/j.cbpa.2008.08.030
Autor:
J A, Tynan, S K, Kim, A R, Mazloom, C, Zhao, G, McLennan, R, Tim, L, Liu, G, Hannum, A, Hull, A T, Bombard, P, Oeth, T, Burcham, D, van den Boom, M, Ehrich
Publikováno v:
Prenatal diagnosis. 36(1)
Clinical performance of a low coverage, low cost, massively parallel sequencing (MPS)-based assay to stratify risk of trisomy 21, 18, and 13 pregnancies was determined.The study included 1100 samples with birth outcome or karyotype results, comprisin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34836dfa985c883d6922f26c79bcc0dd
https://pubmed.ncbi.nlm.nih.gov/26505614
https://pubmed.ncbi.nlm.nih.gov/26505614
Publikováno v:
The Journal of Immunology. 176:4515-4519
Ag, in the form of immune complexes retained on follicular dendritic cells, has been implicated in the development and maintenance of B cell memory. We addressed this question using a H chain transgenic (Tg) mouse model that lacks secreted Ig (mIg),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c3e3d796ccd54c310ebfd0f07a6a9f
https://doi.org/10.4049/jimmunol.176.8.4515
https://doi.org/10.4049/jimmunol.176.8.4515
Autor:
Joanne Daugherty, Mark J Shlomchik, Michelle Tang, Murugappan Ramanathan, Lynn G. Hannum, F. Susan Wong, Charles A Janeway, Li Wen, Irene Visintin
Publikováno v:
Diabetes. 53:2581-2587
B-cells are important in the development of type 1 diabetes, but their role is not completely defined. Although B-cells produce autoantibodies, these are not thought to be pathogenic; however, their antigen-presenting function is postulated to be cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe93aaa60521e43fcccf076cb39f3c58
https://doi.org/10.2337/diabetes.53.10.2581
https://doi.org/10.2337/diabetes.53.10.2581
Publikováno v:
Trends in Immunology. 37:425-426
Although discussions to improve training for immunologists often focus on graduate programs, there are important reasons for teaching undergraduate immunology courses and several best practices utilized by undergraduate faculty. Here, we propose and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736c8801e01d73138f079cfe52d5c8d4
https://doi.org/10.1016/j.it.2016.03.008
https://doi.org/10.1016/j.it.2016.03.008
Autor:
James L. Gombold, Susan R. Weiss, Yvonne Paterson, Mark J. Shlomchik, Amy E. Matthews, Lynn G. Hannum
Publikováno v:
The Journal of Immunology. 167:5254-5263
Intracerebral inoculation with mouse hepatitis virus strain A59 results in viral replication in the CNS and liver. To investigate whether B cells are important for controlling mouse hepatitis virus strain A59 infection, we infected muMT mice who lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f86046d6f287c61a1ac06b445b7f45
https://doi.org/10.4049/jimmunol.167.9.5254
https://doi.org/10.4049/jimmunol.167.9.5254
Publikováno v:
The Journal of Experimental Medicine
Serum antibody (Ab) can play several roles during B cell immune responses. Among these is to promote the deposition of immune complexes (ICs) on follicular dendritic cells (FDCs). ICs on FDCs are generally thought to be critical for normal germinal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225d85b1847be04b65607b7a45af79e9
https://doi.org/10.1084/jem.192.7.931
https://doi.org/10.1084/jem.192.7.931
Autor:
Lynn G. Hannum, Ann M. Haberman, Karen S. Lee, María Colmenares, Stephanie L. Constant, Diane McMahon-Pratt, Peter E. Kima, Mark J. Shlomchik
Publikováno v:
The Journal of Experimental Medicine
We show here that maintenance of Leishmania infections with Leishmania mexicana complex parasites (Leishmania amazonensis and Leishmania pifanoi) is impaired in the absence of circulating antibody. In these studies, we used mice genetically altered t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d72e5e06c8f9aeebd15326f5f92aaa
https://doi.org/10.1084/jem.191.6.1063
https://doi.org/10.1084/jem.191.6.1063
Publikováno v:
The Journal of Experimental Medicine
The precise role of B cells in systemic autoimmunity is incompletely understood. Although B cells are necessary for expression of disease (Chan, O., and M.J. Shlomchik. 1998. J. Immunol. 160:51–59, and Shlomchik, M.J., M.P. Madaio, D. Ni, M. Trouns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c9c5b6e6d04dbfd92550bb95d7129a
https://doi.org/10.1084/jem.189.10.1639
https://doi.org/10.1084/jem.189.10.1639