Zobrazeno 1 - 10
of 40
pro vyhledávání: '"G, Hallström"'
Publikováno v:
Xenobiotica. 30:179-192
1. The metabolism of delmopinol, an inhibitor of plaque formation and gingivitis. has been studied after mouth rinsing or an oral dose of 14C-delmopinol to healthy male volunteers. The metabolite pattern was studied in urine and plasma samples (unhyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5825069cf4da2c8868052c4693caabfc
https://doi.org/10.1080/004982500237767
https://doi.org/10.1080/004982500237767
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(10)
Mass balance and metabolism of formoterol were investigated in six healthy men in an open study. Mean age was 49.7 years (range: 40-63). Simultaneous oral (mean dose 88.6 nmol, 49.3 MBq) and i.v. (mean dose 38.2 nmol, 21.4 MBq) doses of tritium-label
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d0cc49af462ce9b7b9284955978fd20
https://pubmed.ncbi.nlm.nih.gov/10497135
https://pubmed.ncbi.nlm.nih.gov/10497135
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 28(11)
1. The absorption and excretion of delmopinol, an inhibitor of plaque formation and gingivitis, were studied in healthy male volunteers. Each subject received a single dose of a 10-ml aqueous solution of 14C-delmopinol at 2 mg/ml as a 1-min mouth rin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19736aac6a70fb22384d7f8bf6826406
https://pubmed.ncbi.nlm.nih.gov/9879639
https://pubmed.ncbi.nlm.nih.gov/9879639
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(11)
Microsomes from human lung and liver catalyze the formation of fatty acid esters of budesonide, a glucocorticoid used for inhalation treatment of asthma. The conjugation was dependent on coenzyme A and ATP. Addition of free fatty acids to the incubat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::876a55b153e84f5fb044471c36016dcb
https://pubmed.ncbi.nlm.nih.gov/9351909
https://pubmed.ncbi.nlm.nih.gov/9351909
Publikováno v:
Chemico-Biological Interactions. 34:185-200
Pargyline undergoes metabolic N-oxidation in rat and rabbit liver microsomal preparations. The reaction requires oxygen and is NADPH dependent. N-oxidation and N-demethylation are equal in both control and induced rat liver microsomes, while N-oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a481e18da3cd8ff9f26379e7f1aafc90
https://doi.org/10.1016/0009-2797(81)90130-7
https://doi.org/10.1016/0009-2797(81)90130-7
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 11(1)
The effects of methyl, ethyl, isopropyl, isobutyl, and benzyl substituents at the alpha-carbon of N-methyl-2-phenethylamine on the kinetics of its N-demethylation in liver microsomes from both control and phenobarbital pretreated rats were studied. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33491a4a1c4ac9b7088ebfc53c884012
https://pubmed.ncbi.nlm.nih.gov/6132789
https://pubmed.ncbi.nlm.nih.gov/6132789
Publikováno v:
Acta pharmaceutica Suecica. 20(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6017038e22d31f3cc065de5468ec1638
https://pubmed.ncbi.nlm.nih.gov/6421086
https://pubmed.ncbi.nlm.nih.gov/6421086
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 11(1)
Four products of the in vitro oxidative metabolism of the piperidine ring of phencyclidine, 5-(1-phenylcyclohexylamino)valeraldehyde, V; N-(1-phenylcyclohexyl)-1,2,3,4-tetrahydropyridine, VIII; 5-(1-phenylcyclohexylamino)valeric acid, VII; and 1-phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3556eaaa9909ef58c25758d342d4d5ef
https://pubmed.ncbi.nlm.nih.gov/6132795
https://pubmed.ncbi.nlm.nih.gov/6132795
Publikováno v:
Acta pharmaceutica Suecica. 17(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2aa0a1dda90ff184b15d4427b4cc1f4
https://pubmed.ncbi.nlm.nih.gov/7424535
https://pubmed.ncbi.nlm.nih.gov/7424535
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 10(6)
The formation of cytochrome P-450 metabolic intermediary (MI) complexes from a homologous series of alpha-substituted 2-phenylethylamines and corresponding N-hydroxylamines was investigated during NADPH-dependent metabolism in liver microsomes from p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6fa768c6521dbf586c7f979778f38e31
https://pubmed.ncbi.nlm.nih.gov/6130927
https://pubmed.ncbi.nlm.nih.gov/6130927