Zobrazeno 1 - 10
of 77
pro vyhledávání: '"G, Greenspan"'
Autor:
Dan Geiger, G. Greenspan
Publikováno v:
Genetics. 172:2583-2599
Models of background variation in genomic regions form the basis of linkage disequilibrium mapping methods. In this work we analyze a background model that groups SNPs into haplotype blocks and represents the dependencies between blocks by a Markov c
Autor:
F. Gotch, Mark Bower, Dan Geiger, Brian Gazzard, Mark Nelson, Steven Patterson, G. Greenspan, Justin Stebbing
Publikováno v:
Journal of Molecular Evolution. 58:239-251
An emergent problem in the study of pathogen evolution is our ability to determine the extent to which their rapidly evolving genomes recombine. Such information is necessary and essential for locating pathogenicity loci using association studies, an
Autor:
G. Greenspan, Dan Geiger
Publikováno v:
RECOMB
The uneven recombination structure of human DNA has been highlighted by several recent studies. Knowledge of the haplotype blocks generated by this phenomenon can be applied to dramatically increase the statistical power of genetic mapping. Several c
Autor:
G. Greenspan, Dan Geiger
Publikováno v:
ISMB/ECCB (Supplement of Bioinformatics)
Motivation: The presence of millions of single nucleotide polymorphisms (SNPs) in the human genome has spurred interest in genetic mapping methods based on linkage disequilibrium. The recently discovered haplotype block structure of human variation p