Zobrazeno 1 - 10
of 62
pro vyhledávání: '"G, Dytko"'
Autor:
Catherine E. Ellis, Nabil Elshourbagy, Pamela Lane, Laura R. Fitzgerald, Shelagh Wilson, Ping Tsui, Derk J. Bergsma, Robert S. Ames, Kong B. Tan, Henry M. Sarau, Ishrat Jahan Mannan, G. Dytko, Nicholas D. Evans, David A. Campbell, Lynnette McMillan, Heather Minehart, Paul R. Murdock, James J. Foley
Publikováno v:
Biochemical and biophysical research communications. 273(3)
We have identified a cDNA, designated HOFNH30, which encodes a 354 amino acid G-protein-coupled receptor (GPCR). This receptor has 96% amino acid identity to the Jurkat-T cell-derived EDG7 and could be a splice variant. RT-PCR analysis demonstrated t
Publikováno v:
Molecular pharmacology. 47(6)
Thrombin-mediated down-regulation of endothelin (ET) receptors was studied in rat glomerular mesangial cells. Overnight incubation of mesangial cells with thrombin (10 nM) resulted in a significant decrease (67%) in the number of ET receptors, with n
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(1)
Urea is transported from mucosa to serosa across the skin of the stenohaline toad, Bufo marinus, studied under short circuit current (SCC) conditions. Mucosal to serosal transepithelial urea transport (Jm--s(urea)) was markedly and asymmetrically enh
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 263(1)
The effect of thrombin on mesangial cell function was investigated. Thrombin caused a dose-dependent increase in [3H] thymidine incorporation (EC50 = 0.36 +/- 0.09 U/ml), intracellular calcium [(Ca++)i] mobilization (EC50 = 1.9 +/- 0.5 U/ml) and pros
Publikováno v:
The American journal of physiology. 258(1 Pt 2)
We studied the interaction of intracellular pH, exocytosis, and cell calcium on the stimulation of H+ secretion by CO2 in turtle bladder. Intracellular pH was continuously monitored by the fluorescent dye 6-carboxyfluorescein and exocytosis was monit
Autor:
Kenneth A. Newlander, C R Albrightson-Winslow, Nancy Caldwell, L. B. Kinter, Drake S. Eggleston, Michael L. Moore, G. Dytko, Heidi G. Bryan, Bridget Brickson, William F. Huffman
Publikováno v:
Journal of Medicinal Chemistry. 32:880-884
[1-(beta,beta-Pentamethylene-beta-mercaptopropionic acid),2-(O-ethyl)-D- tyrosine,4-valine,9-desglycine]arginine-vasopressin (SK&F 101926, 1), a potent in vivo and in vitro vasopressin V2 receptor antagonist, was recently tested in human volunteers a
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 265(1)
A decrease in extracellular pH is well known to inhibit vasopressin stimulated water flow in the toad bladder. It remains unclear whether this inhibition is the result of the effect of extracellular pH per se or the consequence of altered intracellul
Publikováno v:
Mineral and electrolyte metabolism. 10(4)
Intracellular pH is thought to play an important role in several aspects of cell function including urinary acidification. The turtle urinary bladder is capable of urinary acidification in vitro and it is considered an analogue of the mammalian dista
Publikováno v:
The Journal of laboratory and clinical medicine. 96(3)
In order to investigate a possible role of the microtubules in urinary acidification we measured H+ secretion by the turtle bladder in vitro before and after addition of either colchicine or vinblastine to the serosal phase. Both colchicine and vinbl
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 240(1)
The role of the changes in intracellular concentration of Ca and Mg in Na and H+ transport by the turtle bladder in vitro was studied with the use of the ionophore A23187. This ionophore increases the permeability of living and artificial membranes t