Zobrazeno 1 - 10
of 282
pro vyhledávání: '"G, Dickneite"'
Autor:
H Daniel, Ernst Petzinger, P J Meier, G. Dickneite, Stüber W, M Reers, Jurgen A. Horz, B Hagenbuch, M Wagener, Eckhardt U, B Stieger
Publikováno v:
Hepatology. 24:380-384
The peptidomimetic thrombin inhibitor CRC 220, 4-methoxy-2,3,6-trimethylphenylsulfonyl-L-aspartyl-D-4-amidinop henylalanyl- piperidide, is taken up into isolated rat hepatocytes through active, carrier-mediated transport. This uptake is inhibited by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1666b752c119b1927f97bca0c71a1067
https://doi.org/10.1002/hep.510240215
https://doi.org/10.1002/hep.510240215
Publikováno v:
Biochemical Pharmacology. 52:85-96
CRC 220 (4-methoxy-2, 3, 6-trimethylphenylsulfonyl-L-aspartyl-D-4-amidinophenylalanyl-piperidide) is a competitive peptide-based trombin inhibitor with high affinity to human α-thrombin ( K i 2.5 nM). The amphiphilic compound exhibits virtually no s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::921513dd9d44882c9ef9209b9262b9d1
https://doi.org/10.1016/0006-2952(96)00141-4
https://doi.org/10.1016/0006-2952(96)00141-4
Publikováno v:
Journal of Enzyme Inhibition. 9:61-72
Thrombin inhibitors have been thought to play a pivotal role in myocardial infarct and stroke incidences and their aftermath. Quite some time ago potent synthetic thrombin inhibitors became known based on peptide derivatives D-Phe-Pro-Arg and benzami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a67f2cf5cd0ee6624c61af66896d5ac
https://doi.org/10.3109/14756369509040681
https://doi.org/10.3109/14756369509040681
Autor:
J. M. Hecker, R. Lorenz, R. Appiah, B. Vangerow, M. Loss, R. Kunz, J. Schmidtko, M. Mengel, J. Klempnauer, S. Piepenbrock, G. Dickneite, H. Neidhardt, H. R??ckoldt, M. Winkler
Publikováno v:
Transplantation. 73:675-677
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac8bbd101b21adcabc8753a750a86b7e
https://doi.org/10.1097/00007890-200203150-00003
https://doi.org/10.1097/00007890-200203150-00003
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 17(5)
The ratio of von Willebrand factor (VWF) to FVIII differs among available VWF/FVIII concentrates. Repeated infusions of concentrates with a low VWF:FVIII ratio may expose patients with von Willebrand disease to supranormal FVIII levels. The aim of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a618f29e5744fb854a29571d16bd0c72
https://pubmed.ncbi.nlm.nih.gov/21726357
https://pubmed.ncbi.nlm.nih.gov/21726357
Publikováno v:
Haemophilia.
The ratio of von Willebrand factor (VWF) to FVIII differs among available VWF/FVIII concentrates. Repeated infusions of concentrates with a low VWF:FVIII ratio may expose patients with von Willebrand disease to supranormal FVIII levels. The aim of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de9933ed1972baa717ca438a452b15d5
https://doi.org/10.1111/j.1365-2516.2011.02603.x
https://doi.org/10.1111/j.1365-2516.2011.02603.x
Publikováno v:
Agents and Actions. 39:C121-C124
According to its immunopharmacological profile, 15-deoxyspergualin (15-DOS) has been investigated as to its disease-modifying activity on HgCl2-induced glomerulonephritis (GN) and on tubulointerstitial nephritis (TIN) in Brown-Norway rats. Both model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c23605f393b1e8a3bdcc3ab4f35518d
https://doi.org/10.1007/bf01972741
https://doi.org/10.1007/bf01972741
Publikováno v:
Platelets. 7(5-6)
To prevent r-hirudin induced excess bleeding an animal model was established in pigs for the investigation of an anti-bleeding strategy. We used the Simplate® device to monitor skin bleeding time (SBT) at the inner site of the ear. r-Hirudin infused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d008f8575a3d76a5d69971bfaf08cbc
https://pubmed.ncbi.nlm.nih.gov/21043663
https://pubmed.ncbi.nlm.nih.gov/21043663
Publikováno v:
Inflammation Research. 44:S194-S196
As has been reported previously, models of chronic graft-versus-host (GvH) and systemic lupus erythematosus (SLE)-like diseases are characterized by high IgE and IgG1 immunoglobulin (Ig) levels in the serum. An IL-4 induced pathological expansion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f3bcaae1fc96ce20eade9e0e77a712
https://doi.org/10.1007/bf01778328
https://doi.org/10.1007/bf01778328
Publikováno v:
Cardiovascular surgery (London, England). 11
Factor XIII has a well-established role in natural coagulation and clot stabilization. It is often added back to fibrin sealants that are used in a wide range of surgical settings to achieve successful hemostasis, tissue adhesion and wound healing. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867b9a886fde74643dceec8ceebc52de
https://pubmed.ncbi.nlm.nih.gov/12869983
https://pubmed.ncbi.nlm.nih.gov/12869983