Zobrazeno 1 - 10
of 778
pro vyhledávání: '"G, Curzon"'
Publikováno v:
European Psychiatry. 8:61s-66s
SummaryThe novel antidepressant drug tianeptine had an antidepressant-like effect on a rat model of depression based on the deficit in open field activity observed on the day after 2 h immobilization. Thus, tianeptine (10 mg/kg ip) given 2 h after th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eb8fbd07d60c501be1f4e9ad3f2ee21
https://doi.org/10.1017/s092493380000540x
https://doi.org/10.1017/s092493380000540x
Autor:
G. Curzon
Publikováno v:
Neurochemistry international. 8(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d2f711649dd129a59bc01fd62627da
https://pubmed.ncbi.nlm.nih.gov/20493041
https://pubmed.ncbi.nlm.nih.gov/20493041
Publikováno v:
British Journal of Psychiatry. 160:51-55
A model of depression based on measurements made after restraining rats for two hours has been developed. The model is associated with elevation in corticosterone, reflects the higher incidence of depression in women, and shows increased post-synapti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3747e81a36cf8bd708c753c51a16df67
https://doi.org/10.1192/s0007125000296682
https://doi.org/10.1192/s0007125000296682
Autor:
G. Curzon
Publikováno v:
Annals of the New York Academy of Sciences. 600:521-530
Feeding or food withdrawal can affect the supply of tryptophan to the brain and hence (in some circumstances) 5-HT synthesis therein. Also fenfluramine which releases 5-HT to postsynaptic receptors suppresses appetite, and there are reports that tryp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd5e3e5f364c7cb26de35611069218f
https://doi.org/10.1111/j.1749-6632.1990.tb16907.x
https://doi.org/10.1111/j.1749-6632.1990.tb16907.x
Publikováno v:
Journal of Neural Transmission. 79:93-101
Brain regional 5-hydroxytryptamine (5-HT) and/or 5-hydroxyindoleacetic acid (5-HIAA) concentrations tended to be slightly higher in female rats than in males but differences were substantial only in the hippocampus where female values were 34% and 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ddaee17d354a712e29ff3dc05074d5
https://doi.org/10.1007/bf01251004
https://doi.org/10.1007/bf01251004
Autor:
G, Curzon, E L, Gibson
Publikováno v:
Advances in experimental medicine and biology. 467
Medical and social pressures have led to increased emphasis on dieting. However, there has been a concurrent world wide increase of obesity. Therefore, much attention has been paid to the development of drugs which decrease appetite. The most extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3878276ec8ad0440d3dfaf9b6a1dc98e
https://pubmed.ncbi.nlm.nih.gov/10721044
https://pubmed.ncbi.nlm.nih.gov/10721044
Autor:
E. L. Gibson, G. Curzon
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461371335
Medical and social pressures have led to increased emphasis on dieting. However, there has been a concurrent world wide increase of obesity. Therefore, much attention has been paid to the development of drugs which decrease appetite. The most extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98e8b1314abc0fd17cfa38f755117059
https://doi.org/10.1007/978-1-4615-4709-9_13
https://doi.org/10.1007/978-1-4615-4709-9_13
Autor:
G. Curzon
Publikováno v:
Neurochemistry ISBN: 9781461374688
Almost all reported findings on 5-hydroxytryptamine (5-HT) in depression have been questioned sooner or later. For example, in the 30 years since the concentration of the 5-HT metabolite 5-hydroxyindoleacetic acid in the lumbar CSF was first reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c7f99cadd67d7711e848fb5c8531020
https://doi.org/10.1007/978-1-4615-5405-9_31
https://doi.org/10.1007/978-1-4615-5405-9_31
Publikováno v:
Behavioural pharmacology. 7(2)
Acute (10mg/kg, i.p.) and chronic (10mg/kg/day, i.p. for 10 days) diazepam treatments decreased hippocampal dialysate 5-HT (but not 5-HIAA) concentrations in freely moving rats, suggesting decreased availability of 5-HT to receptors. Twenty-four hour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23fea4bfee513801389adce98b257f52
https://pubmed.ncbi.nlm.nih.gov/11224410
https://pubmed.ncbi.nlm.nih.gov/11224410
Autor:
G. Curzon
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461380269
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef5118427ee220073184fd020379ef29
https://doi.org/10.1007/978-1-4613-0381-7_3
https://doi.org/10.1007/978-1-4613-0381-7_3