Robust and persistent B-cell responses following SARS-CoV-2 vaccine determine protection from SARS-CoV-2 infection

Autor: Joanne Byrne, Lili Gu, Alejandro Garcia-Leon, Colette Marie Gaillard, Gurvin Saini, Dana Alalwan, Julen Tomás-Cortázar, Grace Kenny, Sean Donohue, Bearach Reynolds, Tessa O’Gorman, Alan Landay, Peter Doran, Jannik Stemler, Philipp Koehler, Rebecca Jane Cox, Ole F. Olesen, Jean-Daniel Lelievre, Cathal O’Broin, Stefano Savinelli, Eoin R. Feeney, Jane A. O’Halloran, Aoife Cotter, Mary Horgan, Christine Kelly, Corrina Sadlier, Eoghan de Barra, Oliver A. Cornely, Virginie Gautier, Patrick WG Mallon, All Ireland Infectious Diseases cohort study and VACCELERATE consortium, A. Cotter, E. Muldoon, G. Sheehan, T. McGinty, J. S. Lambert, T. O’Gorman, C. Kelly, K. Leamy, J. Byrne, G. Kenny, K. McCann, R. McCann, C. O’Broin, S. Savinelli, J. O’Halloran, E. Feeney, P. W. G. Mallon, A. Garcia Leon, S. Miles, D. Alalwan, R. Negi, G. Saini, E. Moore, E. de Barra, S. McConkey, K. Hurley, B. Jacob, F. Lyons, M. Horgan, C. Sadlier, T. Bracken, B. Whelan, J Low, O Yousif, B. McNicholas, G. Courtney, C. O’Maoldomhnaigh, P. Gavin, Julia M. Neuhann, Ullrich Bethe, Sarah Heringer, Jon Salmanton-Garcı́a, Lea Tischmann, Arnd Cüppers, Jan Grothe, Antonio J. Carcas, Jesús Frías-Iniesta, Murat Akova, Alejandro Garcia Leon, Patrick Mallon, Riya Negi, Colette Gaillard, Christine Lammens, An Hotterbeekx, Katherine Loens, Surbhi Malhotra-Kumar, Herman Goossens, Samir Kumar-Singh, Franz König, Lusine Yeghiazaryan, Martin Posch

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionA clear immune correlate of protection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has not been defined. We explored antibody, B-cell, and T-cell responses to the third-dose vaccine and relationship to inci

Externí odkaz: https://doaj.org/article/1469edd2e8884d0ab79ea55f12a635fa

Comparison of SARS-CoV-2 Evolution in Paediatric Primary Airway Epithelial Cell Cultures Compared with Vero-Derived Cell Lines

Autor: Connor G. G. Bamford, Lindsay Broadbent, Elihu Aranday-Cortes, Mary McCabe, James McKenna, David G. Courtney, Olivier Touzelet, Ahlam Ali, Grace Roberts, Guillermo Lopez Campos, David Simpson, Conall McCaughey, Derek Fairley, Ken Mills, Ultan F. Power, on behalf of the Breathing Together Investigators

Publikováno v: Viruses, Vol 14, Iss 2, p 325 (2022)

SARS-CoV-2 can efficiently infect both children and adults, albeit with morbidity and mortality positively associated with increasing host age and presence of co-morbidities. SARS-CoV-2 continues to adapt to the human population, resulting in several

Externí odkaz: https://doaj.org/article/7eb0dce777284585ab48e1334ebdc74c

Post-Transcriptional Regulation of Viral RNA through Epitranscriptional Modification

Autor: David G. Courtney

Publikováno v: Cells, Vol 10, Iss 5, p 1129 (2021)

The field of mRNA modifications has been steadily growing in recent years as technologies have improved and the importance of these residues became clear. However, a subfield has also arisen, specifically focused on how these modifications affect vir

Externí odkaz: https://doaj.org/article/4b318683942c4c10a168367814342aab

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