Zobrazeno 1 - 10
of 3 835
pro vyhledávání: '"G, Castro"'
Autor:
Lubayna S. Elahi, Michael C. Condro, Riki Kawaguchi, Yue Qin, Alvaro G. Alvarado, Brandon Gruender, Haocheng Qi, Tie Li, Albert Lai, Maria G. Castro, Pedro R. Lowenstein, Matthew C. Garrett, Harley I. Kornblum
Publikováno v:
npj Metabolic Health and Disease, Vol 2, Iss 1, Pp 1-14 (2024)
Abstract Histone deacetylases (HDACs) have a wide range of targets and can rewire both the chromatin and lipidome of cancer cells. In this study, we show that valproic acid (VPA), a brain penetrant anti-seizure medication and histone deacetylase inhi
Externí odkaz:
https://doaj.org/article/ecf370d8942a4622b169a6b1429e57e4
Publikováno v:
BMC Ecology and Evolution, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Body size and echolocation call frequencies are related in bats. However, it is unclear if this allometry applies to the entire clade. Differences have been suggested between nasal and oral emitting bats, as well as between some t
Externí odkaz:
https://doaj.org/article/38ea6feb61094639aaeb10894c59ec93
Autor:
Erik R. Peterson, Peter Sajjakulnukit, Andrew J. Scott, Caleb Heaslip, Anthony Andren, Kari Wilder-Romans, Weihua Zhou, Sravya Palavalasa, Navyateja Korimerla, Angelica Lin, Alexandra O’Brien, Ayesha Kothari, Zitong Zhao, Li Zhang, Meredith A. Morgan, Sriram Venneti, Carl Koschmann, Nada Jabado, Costas A. Lyssiotis, Maria G. Castro, Daniel R. Wahl
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-19 (2024)
Abstract Background Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPGs), are a fatal form of brain cancer. These tumors often carry a driver mutation on histone H3 converting lysine 27 to methionine (H3K27M). DMG-H3K27M
Externí odkaz:
https://doaj.org/article/1951e061c7ab4540990fd8c2ffa35723
Autor:
Iulia Tapescu, Peter J. Madsen, Pedro R. Lowenstein, Maria G. Castro, Stephen J. Bagley, Yi Fan, Steven Brem
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Originally devised for cancer control, mRNA vaccines have risen to the forefront of medicine as effective instruments for control of infectious disease, notably their pivotal role in combating the COVID-19 pandemic. This review focuses on fundamental
Externí odkaz:
https://doaj.org/article/0e9534d7859743ec97b686ecc2e43474
Publikováno v:
Antimicrobial Stewardship & Healthcare Epidemiology, Vol 4, Pp s46-s46 (2024)
Background: Aztreonam (AZT) is frequently used for the treatment of Enterobacterales-related infections, particularly for patients with penicillin allergy. We aimed to analyze the impact over time of changes in AZT Days of therapy (DOTs) on AZT susce
Externí odkaz:
https://doaj.org/article/b45d252e604d416db1f626e98456ce92
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34652- (2024)
Background: Chronic back pain is a frequent and disabling health problem. There is evidence that ignorance and erroneous beliefs about chronic low back pain among health professionals interfere in the treatment of people who suffer from it. The Healt
Externí odkaz:
https://doaj.org/article/83e77bbb786f4735a1adcd620c66b98e
Autor:
Seethalakshmi Hariharan, Benjamin T. Whitfield, Christopher J. Pirozzi, Matthew S. Waitkus, Michael C. Brown, Michelle L. Bowie, David M. Irvin, Kristen Roso, Rebecca Fuller, Janell Hostettler, Sharvari Dharmaiah, Emiley A. Gibson, Aaron Briley, Avani Mangoli, Casey Fraley, Mariah Shobande, Kevin Stevenson, Gao Zhang, Prit Benny Malgulwar, Hannah Roberts, Martin Roskoski, Ivan Spasojevic, Stephen T. Keir, Yiping He, Maria G. Castro, Jason T. Huse, David M. Ashley
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Stimulating the innate immune system has been explored as a therapeutic option for the treatment of gliomas. Inactivating mutations in ATRX, defining molecular alterations in IDH-mutant astrocytomas, have been implicated in dysfunctional imm
Externí odkaz:
https://doaj.org/article/93956c3a4d2c4721a96aa5db55f8df28
Autor:
Lubayna S. Elahi, Michael C. Condro, Riki Kawaguchi, Yue Qin, Alvaro G. Alvarado, Brandon Gruender, Haocheng Qi, Tie Li, Albert Lai, Maria G. Castro, Pedro R. Lowenstein, Matthew C. Garrett, Harley I. Kornblum
Publikováno v:
npj Metabolic Health and Disease, Vol 2, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/f17ac9f48872451c8adf495dc087b9f1
Autor:
Syed M. Faisal, Jarred E. Clewner, Brooklyn Stack, Maria L. Varela, Andrea Comba, Grace Abbud, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Glioblastoma (GBM) remains a challenge in Neuro‐oncology, with a poor prognosis showing only a 5% survival rate beyond two years. This is primarily due to its aggressiveness and intra‐tumoral heterogeneity, which limits complete surgical
Externí odkaz:
https://doaj.org/article/1538c238cfc34c618bb0253cf99982f3
Autor:
GD Mota, CL Marques, SL Ribeiro, C Albuquerque, G Castro, D Fernandino, F Omura, A Ranzolin, G Resende, N Silva, M Souza, S Studart, R Xavier, M Yazbek, Marcelo M Pinheiro
Publikováno v:
Advances in Rheumatology, Vol 63, Iss 1, Pp 1-9 (2023)
Abstract Background Some studies have suggested the HLA-B27 gene may protect against some infections, as well as it could play a benefit role on the viral clearance, including hepatitis C and HIV. However, there is lack of SARS-CoV-2 pandemic data in
Externí odkaz:
https://doaj.org/article/c91817c8718d446589b95b313e36262c