Zobrazeno 1 - 10 of 827 pro vyhledávání: '"G, Burnett"'
2
Akademický článek
Survival motor neuron deficiency slows myoblast fusion through reduced myomaker and myomixer expression
Autor: Nikki M. McCormack, Eric Villalón, Coralie Viollet, Anthony R. Soltis, Clifton L. Dalgard, Christian L. Lorson, Barrington G. Burnett
Publikováno v: Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 4, Pp 1098-1116 (2021)
Abstract Background Spinal muscular atrophy is an inherited neurodegenerative disease caused by insufficient levels of the survival motor neuron (SMN) protein. Recently approved treatments aimed at increasing SMN protein levels have dramatically impr
Externí odkaz: https://doaj.org/article/f555774c644749c7bb8839ffe2c95e25
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3
Elektronická kniha
Christian Hebraism in the Reformation Era (1500-1660) : Authors, Books, and the Transmission of Jewish Learning
Autor: Stephen G. Burnett
Christian Hebraism in early modern Europe has traditionally been interpreted as the pursuit of a few exceptional scholars, but in the sixteenth century it became an intellectual movement involving hundreds of authors and printers and thousands of rea
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4
Akademický článek
SMN-deficiency disrupts SERCA2 expression and intracellular Ca2+ signaling in cardiomyocytes from SMA mice and patient-derived iPSCs
Autor: Guzal Khayrullina, Kasey E. Moritz, James F. Schooley, Naheed Fatima, Coralie Viollet, Nikki M. McCormack, Jeremy T. Smyth, Martin L. Doughty, Clifton L. Dalgard, Thomas P. Flagg, Barrington G. Burnett
Publikováno v: Skeletal Muscle, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Spinal muscular atrophy (SMA) is a neurodegenerative disease characterized by loss of alpha motor neurons and skeletal muscle atrophy. The disease is caused by mutations of the SMN1 gene that result in reduced functional expression of surviv
Externí odkaz: https://doaj.org/article/40e9130eb6944548a569a8859af78a5f
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5
Akademický článek
Engineering adoptive T cell therapy to co-opt Fas ligand-mediated death signaling in ovarian cancer enhances therapeutic efficacy
Autor: Philip D Greenberg, Kristin G Anderson, Shannon K Oda, Breanna M Bates, Madison G Burnett, Magdalia Rodgers Suarez, Susan L Ruskin
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background In the USA, more than 50% of patients with ovarian cancer die within 5 years of diagnosis, highlighting the need for therapeutic innovations. Mesothelin (MSLN) is a candidate immunotherapy target; it is overexpressed by ovarian tumors and
Externí odkaz: https://doaj.org/article/16c482feb17b4df89dbc5b52b72fb431
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6
Elektronická kniha
Jews, Judaism, and the Reformation in Sixteenth-Century Germany
Autor: Dean Phillip Bell, Stephen G. Burnett
This book represents a multi-disciplinary approach to the problem of the Jews and the German Reformation. The contributions come from both senior and emerging scholars, from North America, Israel, and Europe, to ensure a breadth in perspective. The e
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8
Akademický článek
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9
Akademický článek
CNS uptake of bortezomib is enhanced by P-glycoprotein inhibition: implications for spinal muscular atrophy
Autor: Emily Foran, Deborah Y. Kwon, Jonathan H. Nofziger, Eveline S. Arnold, Matthew D. Hall, Kenneth H. Fischbeck, Barrington G. Burnett
Publikováno v: Neurobiology of Disease, Vol 88, Iss , Pp 118-124 (2016)
The development of therapeutics for neurological disorders is constrained by limited access to the central nervous system (CNS). ATP-binding cassette (ABC) transporters, particularly P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP),
Externí odkaz: https://doaj.org/article/891d7a1cee84474a87764f91c4d60f2e
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