Zobrazeno 1 - 10
of 75
pro vyhledávání: '"G, Beveridge"'
Autor:
Kathleen M. Mulligan, David X. Zheng, James R. Xu, Christopher R. Cullison, Thomas B. Cwalina, Mara G. Beveridge, Jeffrey F. Scott
Publikováno v:
Archives of Dermatological Research. 315:1033-1036
Autor:
Helena Barker, Amanda De Paoli, Erin Tay, Given Lee, Sandra Duffy, Susan A. Charman, Robert T. Jacobs, Jitendra R. Harjani, Longjin Zhong, Marina Chavchich, Wen Wang, Da Hua Shi, Mitch Mathiew, Stephen Brand, Vicky M. Avery, Michael D. Edstein, Jonathan B. Baell, Darren J. Creek, Daniel L. Priebbenow, David M. Shackleford, Julia G. Beveridge, Karen L. White, Elly Crighton
Publikováno v:
Journal of medicinal chemistry. 64(7)
Novel 3,3'-disubstituted-5,5'-bi(1,2,4-triazine) compounds with potent in vitro activity against Plasmodium falciparum parasites were recently discovered. To improve the pharmacokinetic properties of the triazine derivatives, a new structure-activity
Publikováno v:
Journal of Cutaneous Pathology. 45:434-438
Nivolumab is a fully human IgG4 monoclonal antibody directed against programmed cell death protein 1 (PD-1). PD-1 inhibition allows T-cell activation and recruitment to destroy cancer cells. Checkpoint inhibitors have shown significant survival advan
Autor:
Nikolai N Khodarev, Paul Roach, Sean P Pitroda, Daniel W Golden, Mihir Bhayani, Michael Y Shao, Thomas E Darga, Mara G Beveridge, Ravi F Sood, Harold G Sutton, Michael A Beckett, Helena J Mauceri, Mitchell C Posner, Ralph R Weichselbaum
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5821 (2009)
Traditionally IFN/STAT1 signaling is connected with an anti-viral response and pro-apoptotic tumor-suppressor functions. Emerging functions of a constitutively activated IFN/STAT1 pathway suggest an association with an aggressive tumor phenotype. We
Externí odkaz:
https://doaj.org/article/140c66eb354942779b0d25f8b67804dc
Autor:
Elizabeth A. Vecchio, Lauren T. May, Jonathan B. Baell, Silvia C. Teguh, Guy Y. Krippner, Ryan Brady, Daniel L. Priebbenow, Chengxue Qin, Julia G. Beveridge, Minh Deo, Rebecca H. Ritchie, Girdhar Singh Deora, Aaron DeBono
Publikováno v:
Journal of medicinal chemistry. 62(10)
Herein we describe the development of a focused series of functionalized pyridazin-3(2 H)-one-based formyl peptide receptor (FPR) agonists that demonstrate high potency and biased agonism. The compounds described demonstrated biased activation of pro
Autor:
Sandra Duffy, Marina Chavchich, Grennady Wirjanata, Silvia Teguh, Susan A. Charman, Rintis Noviyanti, Jitendra R. Harjani, Leonardo Lucantoni, Lian Xue, Jutta Marfurt, Michael D. Edstein, Ric N. Price, Tamir Dingjan, Stuart A. Ralph, Julia G. Beveridge, Michael A. Walters, Katherine M. Ellis, Scott Blundell, Jonathan B. Baell, Darren J. Creek, Fei Huang, Sabine Fletcher, Sarah Diab, Vicky M. Avery, Jayme L. Dahlin, Francis C. K. Chiu, Kung Ban, Jessica M. Strasser, Matthew E. Cuellar, Da Hua Shi
Publikováno v:
Journal of Medicinal Chemistry. 62(5)
A series of 3,3′-disubstituted 5,5′-bi(1,2,4-triazine) derivatives was synthesized and screened against the erythrocytic stage of Plasmodium falciparum 3D7 line. The most potent dimer, 6k, with an IC50 (50% inhibitory concentration) of 0.008 μM,
Publikováno v:
JAAD Case Reports
Panniculitides are a group of conditions characterized by inflammation of subcutaneous fat.1 Pancreatic panniculitis is a rare lobular panniculitis that appears in roughly 2% to 3% of patients with pancreatic diseases, such as pancreatitis and pancre
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Autor:
Ingrid C. Polcari, Jennifer L. Burns, Mara G. Beveridge, Sarah L. Stein, Barbara A. Hendrickson, Amos Adler
Publikováno v:
Pediatric Dermatology. 29:68-72
Childhood vaccines are a routine part of pediatric care in the United States; clinicians must be able to recognize and interpret associated localized adverse reactions. Redness and induration at the site of injection are commonly reported and are con
Autor:
Ian C. Talbot, Brian P. Saunders, R. John Nicholls, Robin Kenneth Stewart Phillips, Alastair C. Windsor, David J. W. Swain, Iain G. Beveridge, Chris J. Groves
Publikováno v:
Diseases of the Colon & Rectum. 47:123-126
A restorative proctocolectomy or ileal pouch procedure is one of the main surgical options for patients with familial adenomatous polyposis. The main premise underlying the recommendation of a pouch procedure rather than an ileorectal anastomosis is