ARMC5 Mutations in a Large Cohort of Primary Macronodular Adrenal Hyperplasia: Clinical and Functional Consequences

Autor: Xavier Bertagna, Francoise Doullay, Ludivine Drougat, E. Sonnet, Jérôme Bertherat, Joël Coste, Lionel Groussin, Rossella Libé, Françoise Borson-Chazot, Stéphanie Espiard, F. Brucker-Davis, Florence Torremocha, Guillaume Assié, Felix Beuschlein, Constantine A. Stratakis, Bruno Ragazzon, Marie-Laure Raffin-Sanson, G. Barrande, Stephanie Lopez, Karine Perlemoine, Nathalie Chabbert-Buffet, Denis Pinsard, Laurence Guignat

Publikováno v: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2015, 100 (6), pp.E926-E935. ⟨10.1210/jc.2014-4204⟩
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2015, 100 (6), pp.E926-E935. 〈10.1210/jc.2014-4204〉
Journal of Clinical Endocrinology and Metabolism, 2015, 100 (6), pp.E926-E935. ⟨10.1210/jc.2014-4204⟩

International audience; CONTEXT:Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a rare cause of primary adrenal Cushing's syndrome (CS). ARMC5 germline mutations have been identified recently in PBMAH.OBJECTIVE:To determine the prevalen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b58015651154f33524026374fe950e0
https://hal.univ-lorraine.fr/hal-01813998

Expression of Serotonin7Receptor and Coupling of Ectopic Receptors to Protein Kinase A and Ionic Currents in Adrenocorticotropin-Independent Macronodular Adrenal Hyperplasia Causing Cushing’s Syndrome

Autor: Hervé Lefebvre, Dorthe Cartier, Jérôme Bertherat, Hubert Vaudry, Lionel Groussin, Céline Duparc, Estelle Louiset, G. Barrande, V. Contesse

Publikováno v: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2006, 91 (11), pp.4578-4586. ⟨10.1210/jc.2006-0538⟩

In ACTH-independent macronodular adrenal hyperplasia (AIMAH) causing Cushing's syndrome, cortisol secretion is controlled by illegitimate membrane receptors.The aim of the present study was to characterize the pharmacological properties and the trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a247d02dc32fedcb9c31b78aa39c6600
https://doi.org/10.1210/jc.2006-0538

Abnormal Sensitivity to Glucagon and Related Peptides in Primary Adrenal Cushing’s Syndrome

Autor: Céline Duparc, Hervé Lefebvre, Jérôme Bertherat, Lionel Groussin, Estelle Louiset, Rachel Desailloud, Gaëtan Prévost, G. Barrande, Yves Reznik, Françoise Gobet

Publikováno v: Hormone and Metabolic Research
Hormone and Metabolic Research, Thieme Publishing, 2014, 46 (12), pp.876-882. ⟨10.1055/s-0034-1384522⟩

International audience; Illegitimate G-protein coupled receptors are known to control cortisol secretion in adrenal adenomas and bilateral macronodular adrenal hyperplasias (BMAHs) causing Cushing's syndrome. In the present study, we have evaluated t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e473998bab8c209fa626292faf839fcb
https://hal-normandie-univ.archives-ouvertes.fr/hal-01931119

Effect of obesity on diurnal patterns of testosterone and dehydroepiandrosterone in male subjects

Autor: Fabrice Prieur, E. Mongeois, Nancy Vibarel-Rebot, M.-G. Barrande, Françoise Lasne, Aurélie Baillot, Katia Collomp, Alexandre Guimard

Publikováno v: Science & Sports
Science & Sports, Elsevier 2013, 28 (6), pp.331-334. ⟨10.1016/j.scispo.2013.06.001⟩

Objective The aim of this study was to determine the effects of obesity on the waking diurnal testosterone and dehydroepiandrosterone (DHEA) cycles in obese middle-aged male subjects. Methods Saliva samples were collected at awakening and every 3 hou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d2559e85526e8d6af4c571f304c873
https://hal.archives-ouvertes.fr/hal-00936302

Aberrant cortisol regulations in bilateral macronodular adrenal hyperplasia: a frequent finding in a prospective study of 32 patients with overt or subclinical Cushing's syndrome

Autor: Igor Tauveron, Lionel Groussin, Xavier Bertagna, Frédérique Tissier, Joël Coste, Eric Clauser, G. Barrande, Hervé Lefebvre, Christiane Ajzenberg, Jérôme Bertherat, Bertrand Dousset, Laurence Guignat, Rossella Libé

Publikováno v: European journal of endocrinology. 163(1)

ContextACTH-independent macronodular adrenal hyperplasia (AIMAH) is a rare and heterogeneous condition characterized by abnormal steroid production. Cortisol secretion can be regulated by aberrant hormone receptors.ObjectiveA large series of patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64241ce1a46d2aa2e73e7f0f278d2cc7
https://pubmed.ncbi.nlm.nih.gov/20378721