Zobrazeno 1 - 10
of 78
pro vyhledávání: '"G, Ahr"'
Autor:
S. Shakir, R. Foa, C. Donati, Michel Eichelbaum, D.A. Miller, R. Grobe-Einsler, P.A. Th rmann, R. Seitz, T. Kiewitt, A. Vitale, N. Kaplan, L.M. Fuccella, P. Bauer, J. Gueriguian, D. Brocklebank, A. Guarini, F. D rr, G. Ahr, A.J.J. Wood, L. Cardon, R. Krebs, A. Vazquez, R. Temple, U. Streicher-Saied, M. Danhof, F. Wells, K. Summers, K. Lindpaintner, Jean-Pierre Boissel, F. D. Goebel, R. O Neill, U. Klotz, M. Liu, F.R. B hler, J. Ruiz Rosillo, G.F. Torelli, P.A. van Zwieten, J.-M. Husson, M. Drummond, P. Folb, P. Vicini, J. Kuhlmann, M. Korteweg, T.R. Weihrauch, J. Vollmar, R. B. D Agostino, L.F. Gram, Patrice Jaillon, J. M. Wozney, E. Orsini
Publikováno v:
International Journal of Pharmaceutical Medicine. 14:182-197
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 655:286-292
A method is described that combines chiral HPLC and off-line GC with mass-selective detection for the quantitation of the enantiomers of nisoldipine [(+/-)-I] in human plasma. An isotope-labelled internal standard [nine-fold deuterated (+/-)-I] is us
Publikováno v:
Clinical pharmacology and therapeutics. 86(6)
Administering codeine to breast-feeding mothers had been considered safe until the recent death of a breast-fed neonate whose mother had been prescribed codeine. We investigated the risk of opioid poisoning to breast-fed neonates using coupled physio
Publikováno v:
British Journal of Clinical Pharmacology. 31:367-370
Nine young and 12 elderly healthy volunteers received nisoldipine 10 mg once a day for 7 days. Plasma nisoldipine concentrations were measured on Day 1 and on Day 7. Higher plasma drug concentrations were observed in the elderly group than in the you
Autor:
U B, Soetebeer, M O, Schierenberg, J G, Möller, H, Schulz, G, Grünefeld, P, Andresen, G, Blaschke, G, Ahr
Publikováno v:
Journal of chromatography. A. 895(1-2)
The clinical bioanalytical setting is characterized by sample volumes of1 ml biological fluid (e.g. plasma, urine), a range of 3-4 decades of concentrations to be quantified and a limit of quantitation in the microg/l-ng/l range for sets of 100-5000
Publikováno v:
European journal of clinical pharmacology. 55(1)
Objective: The primary aim of the present study was to investigate the effect of ketoconazole on the pharmacokinetics of nisoldipine. Methods: A single dose of nisoldipine 5 mg immediate-release tablet was administered either alone or in combination
Aims During the world-wide clinical development of the HMG-CoA reductase inhibitor cerivastatin, pharmacokinetic data have been collected from studies performed in Europe, North America and Japan, covering different ethnic groups, mainly Caucasians a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95997d64b9bcbff383c3d3fbee6e91f8
https://europepmc.org/articles/PMC1873645/
https://europepmc.org/articles/PMC1873645/
Publikováno v:
International journal of clinical pharmacology and therapeutics. 35(8)
The pharmacokinetics, safety, and tolerability of the novel once-daily "coat-core" formulation of the calcium antagonist nisoldipine were investigated in 4 randomized nonblind studies A-D in 52 healthy volunteers. Immediate-release or intravenous for
Publikováno v:
International journal of clinical pharmacology and therapeutics. 35(6)
To determine the absolute bioavailability of the HMG-CoA reductase inhibitor cerivastatin, 12 healthy young male volunteers received single doses of either 100 micrograms as a 1-minute bolus infusion or 200 micrograms orally as tablets in a controlle
Publikováno v:
European journal of clinical pharmacology. 51(6)
Nisoldipine, a calcium antagonist of the dihydropyridine class, has been used in the treatment of hypertension and angina pectoris. A new controlled-release dosage form (nisoldipine coat-core, NCC) has been developed to allow once daily dosing. In ad