Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Fyodor A Kondrashov"'
Autor:
Marina A Pak, Karina A Markhieva, Mariia S Novikova, Dmitry S Petrov, Ilya S Vorobyev, Ekaterina S Maksimova, Fyodor A Kondrashov, Dmitry N Ivankov
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282689 (2023)
AlphaFold changed the field of structural biology by achieving three-dimensional (3D) structure prediction from protein sequence at experimental quality. The astounding success even led to claims that the protein folding problem is "solved". However,
Externí odkaz:
https://doaj.org/article/f93d385516134f79a976bef3989c0315
Autor:
Louisa Gonzalez Somermeyer, Aubin Fleiss, Alexander S Mishin, Nina G Bozhanova, Anna A Igolkina, Jens Meiler, Maria-Elisenda Alaball Pujol, Ekaterina V Putintseva, Karen S Sarkisyan, Fyodor A Kondrashov
Publikováno v:
eLife, Vol 11 (2022)
Studies of protein fitness landscapes reveal biophysical constraints guiding protein evolution and empower prediction of functional proteins. However, generalisation of these findings is limited due to scarceness of systematic data on fitness landsca
Externí odkaz:
https://doaj.org/article/ed18ecf491af457191a65695ab4e463d
Autor:
Victoria O Pokusaeva, Dinara R Usmanova, Ekaterina V Putintseva, Lorena Espinar, Karen S Sarkisyan, Alexander S Mishin, Natalya S Bogatyreva, Dmitry N Ivankov, Arseniy V Akopyan, Sergey Ya Avvakumov, Inna S Povolotskaya, Guillaume J Filion, Lucas B Carey, Fyodor A Kondrashov
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1008079 (2019)
Characterizing the fitness landscape, a representation of fitness for a large set of genotypes, is key to understanding how genetic information is interpreted to create functional organisms. Here we determined the evolutionarily-relevant segment of t
Externí odkaz:
https://doaj.org/article/e66bf1d0a4ec429799bdc20106b09434
Autor:
Oksana V Arkhipova, Margarita V Meer, Galina V Mikoulinskaia, Marina V Zakharova, Alexander S Galushko, Vasilii K Akimenko, Fyodor A Kondrashov
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125888 (2015)
The origin and evolution of novel biochemical functions remains one of the key questions in molecular evolution. We study recently emerged methacrylate reductase function that is thought to have emerged in the last century and reported in Geobacter s
Externí odkaz:
https://doaj.org/article/fbf02047154e493e9f0cbb354a32dd3f
Autor:
Evgeny A Koblik, Yaroslav A Red'kin, Margarita S Meer, Romain Derelle, Sofia A Golenkina, Fyodor A Kondrashov, Vladimir Yu Arkhipov
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e17716 (2011)
Recent discovery of the Large-billed Reed Warbler (Acrocephalus orinus) in museums and in the wild significantly expanded our knowledge of its morphological traits and genetic variability, and revealed new data on geographical distribution of the bre
Externí odkaz:
https://doaj.org/article/382d7d1c808d4e51baf9337e152cfc01
Autor:
Steffen Schmidt, Anna Gerasimova, Fyodor A Kondrashov, Ivan A Adzhubei, Alexey S Kondrashov, Shamil Sunyaev
Publikováno v:
PLoS Genetics, Vol 4, Iss 12 (2008)
This corrects the article on p. e1000281 in Vol. 4, PMID: 19043566. Hypermutable Non-Synonymous Sites Are Under Stronger Negative Selection.
Externí odkaz:
https://doaj.org/article/9aaae23f5ef544b0937f53e5f88d1b89
Autor:
Steffen Schmidt, Anna Gerasimova, Fyodor A Kondrashov, Ivan A Adzhubei, Ivan A Adzuhbei, Alexey S Kondrashov, Shamil Sunyaev
Publikováno v:
PLoS Genetics, Vol 4, Iss 11, p e1000281 (2008)
Mutation rate varies greatly between nucleotide sites of the human genome and depends both on the global genomic location and the local sequence context of a site. In particular, CpG context elevates the mutation rate by an order of magnitude. Mutati
Externí odkaz:
https://doaj.org/article/d2062b36833943a9937047fa191e4b2b
Autor:
Evgeny I Rogaev, Yuri K Moliaka, Boris A Malyarchuk, Fyodor A Kondrashov, Miroslava V Derenko, Ilya Chumakov, Anastasia P Grigorenko
Publikováno v:
PLoS Biology, Vol 4, Iss 3, p e73 (2006)
Phylogenetic relationships between the extinct woolly mammoth (Mammuthus primigenius), and the Asian (Elephas maximus) and African savanna (Loxodonta africana) elephants remain unresolved. Here, we report the sequence of the complete mitochondrial ge
Externí odkaz:
https://doaj.org/article/0ca52670afaf4c6dbdc05c2aedaa7ae2
Publikováno v:
Bulletin of Mathematical Biology. 85
Autor:
Maria A. Andrianova, Vladimir B. Seplyarskiy, Mariona Terradas, Ana Beatriz Sánchez-Heras, Pilar Mur, José Luis Soto, Gemma Aiza, Fyodor A. Kondrashov, Alexey S. Kondrashov, Georgii A. Bazykin, Laura Valle
Mutational processes in germline and in somatic cells are vastly different, and it remains unclear how the same genetic background affects somatic and transmissible mutations. Here, we estimate the impact of an inherited pathogenic variant in the exo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce83e8aeb71867149a9e71e0219f1408
https://doi.org/10.1101/2022.07.20.500591
https://doi.org/10.1101/2022.07.20.500591