Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Fw, Ruscetti"'
Publikováno v:
Molecular Medicine. 2:38-49
IgE/anti-IgE immune complexes (IgE-IC) induce the release of multiple mediators from monocytes/macrophages and the monocytic cell line U937 following the ligation of the low-affinity Fce receptors (FceRII/CD23). These effects are mediated through an
Publikováno v:
Blood. 85:3594-3601
Early thymocytes undergo extensive proliferation after their entry into the thymus, but cellular interactions and cytokines regulating this intrathymic step remain to be determined. We analyzed the effects of various T-cell growth factors and cellula
Publikováno v:
Blood. 84:125-132
Interleukin-1 (IL-1) has been shown to stimulate hematopoietic progenitor cell growth both in vitro and in vivo. Although IL-1 alone lacks the ability to promote hematopoietic progenitor growth in vitro, it is a potent synergistic factor in combinati
Autor:
K Hestdal, SE Jacobsen, FW Ruscetti, CM Dubois, DL Longo, R Chizzonite, JJ Oppenheim, JR Keller
Publikováno v:
Blood. 80:2486-2494
To determine the mechanism(s) by which interleukin-1 (IL-1) promotes granulopoiesis in vivo, we examined the effect of in vivo administration of IL-1 alpha on colony-stimulating factor (CSF) receptor expression on bone marrow cells (BMCs) and whether
Publikováno v:
Blood. 78:2841-2847
Interleukin-1 (IL-1) has profound stimulatory effects on hematopoiesis but the mechanism(s) of action remain unknown. The direct action of IL- 1 on hematopoietic progenitor cells requires the presence of a specific IL-1 receptor (IL-1R). In this repo
Autor:
Patricia E. Berg, Sidney W. Fu, Donna M. Williams, B. D. Smith, Judith E. Karp, FW Ruscetti, Frederick G. Behm, David L. Becton, Susanne B. Haga, Douglas D. Ross, Myron Chang, W. D. Hankins, Susana C. Raimondi
Publikováno v:
Leukemia. 14(11)
Aberrant expression of homeobox genes has been described in primary leukemia blasts. We recently cloned a new cDNA, BP1, which is a member of the homeobox gene family. BP1 expression was investigated in bone marrow samples from acute myeloid leukemia
Publikováno v:
Blood. 88(3)
Because leukemia inhibitory factor (LIF) has little or no effect on murine hematopoietic progenitor cell growth yet enhances hematopoiesis in vivo, we sought to determine whether the effects of LIF were directly or indirectly mediated, or a combinati
Autor:
Sten Eirik Waelgaard Jacobsen, Fw, Ruscetti, Okkenhaug C, Lien E, Ortiz M, Op, Veiby, Jr, Keller
Publikováno v:
Europe PubMed Central
While interleukin-1 (IL-1) and IL-6 have been demonstrated to synergize with colony-stimulating factors (CSFs) and stem cell factor (SCF) to stimulate myeloid colony formation of primitive hematopoietic progenitor cells, it has not yet been establish
Publikováno v:
Blood. 83(11)
The cell-surface receptor c-kit and its cognate ligand stem-cell factor (SCF) or steel factor (SLF) are important for the maintenance of hematopoiesis both in vitro and in vivo. Transforming growth factor- beta (TGF-beta) has been shown to be a poten
Autor:
K Grzegorzewski, KL Komschlies, M Mori, K Kaneda, N Usui, CR Faltynek, JR Keller, FW Ruscetti, RH Wiltrout
Publikováno v:
Blood. 83(2)
The administration of recombinant human interleukin-7 (rhIL-7) to mice twice a day for 7 days does not appreciably change bone marrow (BM) cellularity, but does result in a threefold to fivefold increase in the total number of leukocytes in the splee