Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Fuzzy binding"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The Wnt signalling pathway plays key roles in cell proliferation, differentiation and fate decisions in embryonic development and maintenance of adult tissues, and the twelve Armadillo (ARM) repeat-containing protein β-catenin acts as the signal tra
Externí odkaz:
https://doaj.org/article/62aa54168eef4f8195b0396f0d261dee
Publikováno v:
Open Biology, Vol 11, Iss 10 (2021)
Our notions of protein function have long been determined by the protein structure–function paradigm. However, the idea that protein function is dictated by a prerequisite complementarity of shapes at the binding interface is becoming increasingly
Externí odkaz:
https://doaj.org/article/fd8b6000fbc843948af256ccfc1f9e6e
Autor:
Mike P. Williamson
Publikováno v:
Life; Volume 13; Issue 4; Pages: 855
Our understanding of protein binding interactions has matured significantly over the last few years, largely as a result of trying to make sense of the binding interactions of intrinsically disordered proteins. Here, we bring together some disparate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73583c2e26ba2dc133d9f963864bc1a9
Akademický článek
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The Wnt signalling pathway plays key roles in cell proliferation, differentiation and fate decisions in embryonic development and maintenance of adult tissues, and the twelve Armadillo (ARM) repeat-containing protein β-catenin acts as the signal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf06ee0c835933422ac3239a1925958
https://www.repository.cam.ac.uk/handle/1810/338457
https://www.repository.cam.ac.uk/handle/1810/338457
Publikováno v:
Open Biology, Vol 11, Iss 10 (2021)
Open Biology
Open Biology
Our notions of protein function have long been determined by the protein structure–function paradigm. However, the idea that protein function is dictated by a prerequisite complementarity of shapes at the binding interface is becoming increasingly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7277e6771600687d809c24ca35306e
https://royalsocietypublishing.org/doi/10.1098/rsob.210222
https://royalsocietypublishing.org/doi/10.1098/rsob.210222
Autor:
Fuxreiter, M.
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8615, p 8615 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Disordered proteins often act as interaction hubs in cellular pathways, via the specific recognition of a distinguished set of partners. While disordered regions can adopt a well-defined conformation upon binding, the coupled folding to binding model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5720273a5ff0cb1c499867223b739508
https://www.mdpi.com/1422-0067/21/22/8615
https://www.mdpi.com/1422-0067/21/22/8615
Akademický článek
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The human proteome includes many proteins that are entirely disordered or contain long disordered regions. Although these proteins are linked with many diseases, there are currently no clinically-approved drugs that have been shown to target these pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cdd98d7e20b092c337cca8bbafd73c4
Akademický článek
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