Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Fuying Gao"'
Autor:
Jennifer M. Achiro, Yang Tao, Fuying Gao, Chia-Ho Lin, Marika Watanabe, Sylvia Neumann, Giovanni Coppola, Douglas L. Black, Kelsey C. Martin
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Aging-related memory impairment and pathological memory disorders such as Alzheimer’s disease differ between males and females, and yet little is known about how aging-related changes in the transcriptome and chromatin environment differ between se
Externí odkaz:
https://doaj.org/article/40dfcd13efbb453ea7a5c84a591776c2
Autor:
Sree Deepthi Muthukrishnan, Riki Kawaguchi, Pooja Nair, Rachna Prasad, Yue Qin, Maverick Johnson, Qing Wang, Nathan VanderVeer-Harris, Amy Pham, Alvaro G. Alvarado, Michael C. Condro, Fuying Gao, Raymond Gau, Maria G. Castro, Pedro R. Lowenstein, Arjun Deb, Jason D. Hinman, Frank Pajonk, Terry C. Burns, Steven A. Goldman, Daniel H. Geschwind, Harley I. Kornblum
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Therapeutic stress induces phenotypic plasticity in glioma stem cells although the mechanisms underlying this remain poorly understood. Here, the authors show that P300 mediates the radiation-induced vascular-like conversion of glioma stem cells to p
Externí odkaz:
https://doaj.org/article/2f813af486a84bc6939ddacebcf2e7f8
Autor:
Ngan Pan Bennett Au, Gajendra Kumar, Pallavi Asthana, Fuying Gao, Riki Kawaguchi, Raymond Chuen Chung Chang, Kwok Fai So, Yang Hu, Daniel H. Geschwind, Giovanni Coppola, Chi Him Eddie Ma
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-16 (2022)
Abstract Adult mammalian injured axons regenerate over short-distance in the peripheral nervous system (PNS) while the axons in the central nervous system (CNS) are unable to regrow after injury. Here, we demonstrated that Lycium barbarum polysacchar
Externí odkaz:
https://doaj.org/article/59d7549c2a1b4038917bf05b09f9ef36
Autor:
Sofia Pereira das Neves, João Carlos Sousa, Ricardo Magalhães, Fuying Gao, Giovanni Coppola, Sebatien Mériaux, Fawzi Boumezbeur, Nuno Sousa, João José Cerqueira, Fernanda Marques
Publikováno v:
Cells, Vol 12, Iss 20, p 2484 (2023)
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that presents a largely unknown etiopathology. The presence of reactive astrocytes in MS lesions has been described for a long time; however, the role that these
Externí odkaz:
https://doaj.org/article/c6a7058d971d4d6da104d691d7ab89c3
Autor:
Maureen M Sampson, Katherine M Myers Gschweng, Ben J Hardcastle, Shivan L Bonanno, Tyler R Sizemore, Rebecca C Arnold, Fuying Gao, Andrew M Dacks, Mark A Frye, David E Krantz
Publikováno v:
PLoS Genetics, Vol 16, Iss 8, p e1009003 (2020)
Sensory systems rely on neuromodulators, such as serotonin, to provide flexibility for information processing as stimuli vary, such as light intensity throughout the day. Serotonergic neurons broadly innervate the optic ganglia of Drosophila melanoga
Externí odkaz:
https://doaj.org/article/3b1402a1bdbe4d37b3957fd562752152
Autor:
Enrique J. Cobos, Chelsea A. Nickerson, Fuying Gao, Vijayendran Chandran, Inmaculada Bravo-Caparrós, Rafael González-Cano, Priscilla Riva, Nick A. Andrews, Alban Latremoliere, Corey R. Seehus, Gloria Perazzoli, Francisco R. Nieto, Nicole Joller, Michio W. Painter, Chi Him Eddie Ma, Takao Omura, Elissa J. Chesler, Daniel H. Geschwind, Giovanni Coppola, Manu Rangachari, Clifford J. Woolf, Michael Costigan
Publikováno v:
Cell Reports, Vol 22, Iss 5, Pp 1301-1312 (2018)
Summary: Chronic neuropathic pain is a major morbidity of neural injury, yet its mechanisms are incompletely understood. Hypersensitivity to previously non-noxious stimuli (allodynia) is a common symptom. Here, we demonstrate that the onset of cold h
Externí odkaz:
https://doaj.org/article/13a9fb8f80d74f569011eeba624c7454
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
SMARCB1 mutations predispose to rhabdoid tumors and schwannomas but the mechanisms underlying the tumor type specificity are unknown. Here the authors present new mouse models and show that early Smarcb1 loss causes rhabdoid tumors whereas loss at la
Externí odkaz:
https://doaj.org/article/1faf2971b5a4423bb8a856e7f90310eb
Autor:
Victoria J Butler, Fuying Gao, Christian I Corrales, Wilian A Cortopassi, Benjamin Caballero, Mihir Vohra, Kaveh Ashrafi, Ana Maria Cuervo, Matthew P Jacobson, Giovanni Coppola, Aimee W Kao
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008295 (2019)
The progressive failure of protein homeostasis is a hallmark of aging and a common feature in neurodegenerative disease. As the enzymes executing the final stages of autophagy, lysosomal proteases are key contributors to the maintenance of protein ho
Externí odkaz:
https://doaj.org/article/28ae161b4c77481f8ab396351dac3ed4
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212039 (2019)
Mammalian microRNAs (miRNAs) play a critical role in modulating the response of immune cells to stimuli. Cannabinoids are known to exert beneficial actions such as neuroprotection and immunosuppressive activities. However, the underlying mechanisms w
Externí odkaz:
https://doaj.org/article/425d080163c34eecbcc0cb6cefa63573
Autor:
Sharan Paul, Lance Pflieger, Warunee Dansithong, Karla P. Figueroa, Fuying Gao, Giovanni Coppola, Stefan M. Pulst
Publikováno v:
Biology Open, Vol 5, Iss 3, Pp 300-310 (2016)
We developed an adenoviral vector, in which Yamanaka's four reprogramming factors (RFs) were controlled by individual CMV promoters in a single cassette (Ad-SOcMK). This permitted coordinated expression of RFs (SOX2, OCT3/4, c-MYC and KLF4) in a cell
Externí odkaz:
https://doaj.org/article/c65c1114de0c4010a5dfdc8c2dae2b27