Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Futwan A. Al‐Mohanna"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Recent pharmacological studies demonstrate a role for zinc (Zn2+) in shaping intracellular calcium (Ca2+) dynamics and vice versa in excitable cells including neurons and cardiomyocytes. Herein, we sought to examine the dynamic of intracellular relea
Externí odkaz:
https://doaj.org/article/60699c021fb743d48bc75ed99b788a6c
Autor:
Angela Inglis, Rosario Ubungen, Sarah Farooq, Princess Mata, Jennifer Thiam, Soad Saleh, Sherin Shibin, Futwan A. Al-Mohanna, Kate S. Collison
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-26 (2021)
Abstract Background The ever-increasing prevalence of diabetes and associated comorbidities serves to highlight the necessity of biologically relevant small-animal models to investigate its etiology, pathology and treatment. Although the C57BL/6 J mo
Externí odkaz:
https://doaj.org/article/30e354ae34004166be3b788df7c73e40
Autor:
Praveen M. Varghese, Shuvechha Mukherjee, Futwan A. Al-Mohanna, Souad M. Saleh, Fahad N. Almajhdi, Nazar Beirag, Saad H. Alkahtani, Reena Rajkumari, Beatrice Nal Rogier, Robert B. Sim, Susan Idicula-Thomas, Taruna Madan, Valarmathy Murugaiah, Uday Kishore
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The complement system is designed to recognise and eliminate invading pathogens via activation of classical, alternative and lectin pathways. Human properdin stabilises the alternative pathway C3 convertase, resulting in an amplification loop that le
Externí odkaz:
https://doaj.org/article/b389acf03e7945558cd931b8c8ff9fed
Autor:
Faisal A. Al-Allaf, Zainularifeen Abduljaleel, Mohammad Athar, Mohiuddin M. Taher, Wajahatullah Khan, Huseyin Mehmet, Mukaddes Colakogullari, Sophia Apostolidou, Brian Bigger, Simon Waddington, Charles Coutelle, Michael Themis, Mohammed N. Al-Ahdal, Futwan A. Al-Mohanna, Zuhair N. Al-Hassnan, Abdellatif Bouazzaoui
Publikováno v:
Non-coding RNA Research, Vol 4, Iss 1, Pp 1-14 (2019)
Internal ribosome entry site (IRES) sequences have become a valuable tool in the construction of gene transfer and therapeutic vectors for multi-cistronic gene expression from a single mRNA transcript. The optimal conditions for effective use of this
Externí odkaz:
https://doaj.org/article/e7460ad473a841058174a80c260fe241
Autor:
Praveen M. Varghese, Valarmathy Murugaiah, Nazar Beirag, Nigel Temperton, Haseeb A. Khan, Salman H. Alrokayan, Mohammed N. Al-Ahdal, Beatrice Nal, Futwan A. Al-Mohanna, Robert B. Sim, Uday Kishore
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
C4b Binding Protein (C4BP) is a major fluid phase inhibitor of the classical and lectin pathways of the complement system. Complement inhibition is achieved by binding to and restricting the role of activated complement component C4b. C4BP functions
Externí odkaz:
https://doaj.org/article/6244d0b5bb80483e8c4651b6363063f7
Autor:
Valarmathy Murugaiah, Praveen M. Varghese, Soad M. Saleh, Anthony G. Tsolaki, Salman H. Alrokayan, Haseeb A. Khan, Kate S. Collison, Robert B. Sim, Béatrice Nal, Futwan A. Al-Mohanna, Uday Kishore
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The complement system is an ancient innate immune defense mechanism that can recognize molecular patterns on the invading pathogens. Factor H, as an inhibitor of the alternative pathway, down-regulates complement activation on the host cell surface.
Externí odkaz:
https://doaj.org/article/0a82a81391d645008c3a4433be53c3e5
Autor:
Kate S. Collison, Zakia Maqbool, Soad M. Saleh, Angela Inglis, Nadine J. Makhoul, Razan Bakheet, Mohammed Al-Johi, Rana Al-Rabiah, Marya Z. Zaidi, Futwan A. Al-Mohanna
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 8, Pp 1521-1537 (2009)
The effects of dietary monosodium glutamate (MSG) on trans-fatty acid (TFA)-induced nonalcoholic fatty liver disease (NAFLD) are addressed in an animal model. We used Affymetrix microarray analysis to investigate hepatic gene expression and the contr
Externí odkaz:
https://doaj.org/article/c34092a312de47f282992a7ae3fbf8df
Autor:
Yufei Shi, Futwan A. Al-Mohanna, Ali S. Alzahrani, Brian F. Meyer, Abdullah M. Assiri, Falah Almohanna, Khalid S.A. Khabar, Ibrahim Al-Jammaz, Monther Al-Alwan, Suhad Al-Yahya, Yousif H. Al-Malki, Huda A. BinEssa, Minjing Zou
Fig. S1. Up-regulation of thyroid hormone synthesis-related genes in the BVE-Ctnnb1null thyroid tumors. Data are expressed as fold changes between BVE-Ctnnb1null and BVE tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043c3fc3e82e43654a919e52983983da
https://doi.org/10.1158/1535-7163.22521871.v1
https://doi.org/10.1158/1535-7163.22521871.v1
Autor:
Yufei Shi, Futwan A. Al-Mohanna, Ali S. Alzahrani, Brian F. Meyer, Abdullah M. Assiri, Falah Almohanna, Khalid S.A. Khabar, Ibrahim Al-Jammaz, Monther Al-Alwan, Suhad Al-Yahya, Yousif H. Al-Malki, Huda A. BinEssa, Minjing Zou
BRAFV600E mutation is the most frequent genetic alteration in papillary thyroid cancer (PTC). β-Catenin (Ctnnb1) is a key downstream component of canonical Wnt signaling pathway and is frequently overexpressed in PTC. BRAFV600E-driven tumors have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190cd776a9698e2d2e090166b68c8ccd
https://doi.org/10.1158/1535-7163.c.6543208
https://doi.org/10.1158/1535-7163.c.6543208
Autor:
Yufei Shi, Brian F. Meyer, Abdullah M. Assiri, Ali S. Alzahrani, Catrin Pritchard, Shioko Kimura, René St-Arnaud, Ranjit S. Parhar, Futwan A. Al-Mohanna, Huda A. BinEssa, Essa Y. Baitei, Minjing Zou
Supplementary Table 2. Differentially expressed vitamin D responsive genes in BVECyp24a1-wt and BVECyp24a1-null cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ac78ef45a0944dd34a41f14679b0d1
https://doi.org/10.1158/0008-5472.22418057.v1
https://doi.org/10.1158/0008-5472.22418057.v1