Zobrazeno 1 - 10
of 2 713
pro vyhledávání: '"Futreal"'
Autor:
Chenyang Li, Thinh T. Nguyen, Jian-Rong Li, Xingzhi Song, Junya Fujimoto, Latasha Little, Curtis Gumb, Chi-Wan B. Chow, Ignacio I. Wistuba, Andrew P. Futreal, Jianhua Zhang, Shawna M. Hubert, John V. Heymach, Jia Wu, Christopher I. Amos, Jianjun Zhang, Chao Cheng
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-14 (2024)
Abstract Lung Cancer remains the leading cause of cancer deaths in the USA and worldwide. Non-small cell lung cancer (NSCLC) harbors high transcriptomic intratumor heterogeneity (RNA-ITH) that limits the reproducibility of expression-based prognostic
Externí odkaz:
https://doaj.org/article/b6fe0a65261748579d8ae587987a1d01
Autor:
Chia-Chin Wu, Licai Huang, Zhongting Zhang, Zhenlin Ju, Xingzhi Song, E. Anders Kolb, Wendong Zhang, Jonathan Gill, Min Ha, Malcolm A. Smith, Peter Houghton, Christopher L. Morton, Raushan Kurmasheva, John Maris, Yael Mosse, Yiling Lu, Richard Gorlick, P. Andrew Futreal, Hannah C. Beird
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Osteosarcoma is the most common primary bone malignancy in children and young adults, and it has few treatment options. As a result, there has been little improvement in survival outcomes in the past few decades. The need for models to test
Externí odkaz:
https://doaj.org/article/f8e627346ea440b7a5955c5d78e43866
Autor:
Jiahui Jiang, Yunhe Liu, Jiangjiang Qin, Jianfeng Chen, Jingjing Wu, Melissa P. Pizzi, Rossana Lazcano, Kohei Yamashita, Zhiyuan Xu, Guangsheng Pei, Kyung Serk Cho, Yanshuo Chu, Ansam Sinjab, Fuduan Peng, Xinmiao Yan, Guangchun Han, Ruiping Wang, Enyu Dai, Yibo Dai, Bogdan A. Czerniak, Andrew Futreal, Anirban Maitra, Alexander Lazar, Humam Kadara, Amir A. Jazaeri, Xiangdong Cheng, Jaffer Ajani, Jianjun Gao, Jian Hu, Linghua Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Recent advances in spatial transcriptomics (ST) techniques provide valuable insights into cellular interactions within the tumor microenvironment (TME). However, most analytical tools lack consideration of histological features and rely on m
Externí odkaz:
https://doaj.org/article/dd6c8079518149ec919676d74198ca4c
Intratumoral microbiome of adenoid cystic carcinomas and comparison with other head and neck cancers
Autor:
Tatiana V. Karpinets, Yoshitsugu Mitani, Chia-Chi Chang, Xiaogang Wu, Xingzhi Song, Ivonne I. Flores, Lauren K. McDaniel, Yasmine M. Hoballah, Fabiana J. Veguilla, Renata Ferrarotto, Lauren E. Colbert, Nadim J. Ajami, Robert R. Jenq, Jianhua Zhang, Andrew P. Futreal, Adel K. El-Naggar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Adenoid cystic carcinoma (ACC) is a rare, usually slow-growing yet aggressive head and neck malignancy. Despite its clinical significance, our understanding of the cellular evolution and microenvironment in ACC remains limited. We investigat
Externí odkaz:
https://doaj.org/article/e1c7c9a7f34347698b377e27634d3bc8
Autor:
Eswaran Devarajan, R. Eric Davis, Hannah C. Beird, Wei-Lien Wang, V. Behrana Jensen, Arumugam Jayakumar, Cheuk Hong Leung, Heather Y. Lin, Chia-Chin Wu, Stephanie A. Ihezie, Jen-Wei Tsai, P. Andrew Futreal, Valerae O. Lewis
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Lung metastases are the primary cause of death for osteosarcoma (OS) patients. We recently validated interleukin-11 receptor α (IL-11Rα) as a molecular target for the inhibition of OS lung metastases. Since there is no clinically approved
Externí odkaz:
https://doaj.org/article/82384a0da19f427989951c00e219d5ff
Autor:
E.G. Engelhardt, R.S.J.M. Schmitz, M.A. Gerritsma, C.M.T. Sondermeijer, E. Verschuur, J.H.E. Houtzager, R. Griffioen, N. Bijker, R.M. Mann, V. Retèl, F.H. van Duijnhoven, J. Wesseling, E.M.A. Bleiker, Alastair Thompson, Serena Nik-Zainal, Elinor J. Sawyer, Helen Davies, Andrew Futreal, Nicholas Navin, E. Shelley Hwang, Jos Jonkers, Jacco van Rheenen, Fariba Behbod, Esther H. Lips, Marjanka Schmidt, Lodewyk F.A. Wessels, Daniel Rea, Proteeti Bhattacharjee, Hilary Stobart, Deborah Collyar, Donna Pinto, Marja van Oirsouw, S. Alaeikhanehshir, L. Elshof
Publikováno v:
Breast, Vol 77, Iss , Pp 103764- (2024)
Background: Ductal carcinoma in situ (DCIS) can progress to invasive breast cancer (IBC), but often never will. As we cannot predict accurately which DCIS-lesions will or will not progress to IBC, almost all women with DCIS undergo breast-conserving
Externí odkaz:
https://doaj.org/article/bc84270199394f7bb7028854a77ee924
Autor:
Huang Jing, Wei Wen, Zhang Jane, Liu Guoying, Bignell Graham R, Stratton Michael R, Futreal P, Wooster Richard, Jones Keith W, Shapero Michael H
Publikováno v:
Human Genomics, Vol 1, Iss 4, Pp 287-299 (2004)
Abstract Changes in DNA copy number are one of the hallmarks of the genetic instability common to most human cancers. Previous micro-array-based methods have been used to identify chromosomal gains and losses; however, they are unable to genotype all
Externí odkaz:
https://doaj.org/article/8fbc1d5a402940b59124f5d1c18c9dd1
Autor:
Suet-Ying Kwan, Kristyn A. Gonzales, Mohamed A. Jamal, Heather L. Stevenson, Lin Tan, Philip L. Lorenzi, P. Andrew Futreal, Ernest T. Hawk, Joseph B. McCormick, Susan P. Fisher-Hoch, Robert R. Jenq, Laura Beretta
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The gut microbiota drives progression to liver fibrosis, the main determinant of mortality in metabolic dysfunction-associated steatohepatitis (MASH). In this study, we aimed to identify bacterial species associated with protection against liver fibr
Externí odkaz:
https://doaj.org/article/024dc3e0692f4057b109c7aedd234a0a
Autor:
Beird, Hannah C., Cloutier, Jeffrey M., Gokgoz, Nalan, Eeles, Christopher, Griffin, Anthony M., Ingram, Davis R., Wani, Khalida M., Segura, Rossana Lazcano, Cohen, Luca, Ho, Carl, Wunder, Jay S., Andrulis, Irene L., Futreal, P. Andrew, Haibe-Kains, Benjamin, Lazar, Alexander J., Wang, Wei-Lien, Przybyl, Joanna, Demicco, Elizabeth G.
Publikováno v:
In Laboratory Investigation November 2024 104(11)
Autor:
Thompson, Alastair, Nik-Zainal, Serena, Sawyer, Elinor J., Davies, Helen, Futreal, Andrew, Navin, Nicholas, Hwang, E. Shelley, Jonkers, Jos, van Rheenen, Jacco, Behbod, Fariba, Lips, Esther H., Schmidt, Marjanka, Wessels, Lodewyk F.A., Rea, Daniel, Bhattacharjee, Proteeti, Stobart, Hilary, Collyar, Deborah, Pinto, Donna, van Oirsouw, Marja, Alaeikhanehshir, S., Elshof, L., Engelhardt, E.G., Schmitz, R.S.J.M., Gerritsma, M.A., Sondermeijer, C.M.T., Verschuur, E., Houtzager, J.H.E., Griffioen, R., Bijker, N., Mann, R.M., Retèl, V., van Duijnhoven, F.H., Wesseling, J., Bleiker, E.M.A.
Publikováno v:
In The Breast October 2024 77